Publications by authors named "Alfredo Castello"

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Avian-origin influenza A viruses tolerate elevated pyrexic temperatures in mammals.
Matthew L Turnbull, Yingxue Wang, Simon Clare, Gauthier Lieber, Stephanie L Williams, Alfredo Castello

Science· November 2025

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RNA-binding proteins orchestrating immunity in plants.
Marcel Bach-Pages, Athira Menon, Brett Wadley, Alfredo Castello, Gail M Preston

Plant J· September 2025

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Uukuniemi virus infection causes a pervasive remodelling of the RNA-binding proteome in tick cells.
Alexandra Wilson, Wael Kamel, Kelsey Davies, Zaydah R De Laurent, Rozeena Arif, Alfredo Castello

PLoS Pathog· August 2025

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Omics Analyses Uncover Host Networks Defining Virus-Permissive and -Hostile Cellular States.
Honglin Chen, Philip D Charles, Quan Gu, Sabrina Liberatori, David L Robertson, Alfredo Castello

Mol Cell Proteomics· May 2025

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The PAZ domain of Dicer 2 is critical for accurate and high-fidelity size determination of virus-derived small interfering RNAs.
Melinda Reuter, Rhys H Parry, Melanie McFarlane, Rommel J Gestuveo, Rozeena Arif, Alfredo Castello

RNA· April 2025

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Nuclear RNA-binding proteins meet cytoplasmic viruses.
Alfredo Castello, Wael Kamel

RNA· February 2025

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Alphavirus infection triggers selective cytoplasmic translocation of nuclear RBPs with moonlighting antiviral roles.
Wael Kamel, Vincenzo Ruscica, Azman Embarc-Buh, Zaydah R de Laurent, Manuel Garcia-Moreno, Alfredo Castello

Mol Cell· December 2024

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Absolute quantitative and base-resolution sequencing reveals comprehensive landscape of pseudouridine across the human transcriptome.
Haiqi Xu, Linzhen Kong, Jingfei Cheng, Khatoun Al Moussawi, Xiufei Chen, Alfredo Castello

Nat Methods· November 2024

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The molecular dissection of TRIM25's RNA-binding mechanism provides key insights into its antiviral activity.
Lucía Álvarez, Kevin Haubrich, Louisa Iselin, Laurent Gillioz, Vincenzo Ruscica, Alfredo Castello

Nat Commun· October 2024

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Exploring the expanding universe of host-virus interactions mediated by viral RNA.
Alfredo Castello, Lucía Álvarez, Wael Kamel, Louisa Iselin, Janosch Hennig

Mol Cell· October 2024

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Repurposed 3D Printer Allows Economical and Programmable Fraction Collection for Proteomics of Nanogram Scale Samples.
Eduardo S Kitano, Gareth Nisbet, Yana Demyanenko, Katarzyna M Kowalczyk, Louisa Iselin, Alfredo Castello

Anal Chem· July 2024

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Viral RNA Is a Hub for Critical Host-Virus Interactions.
Alfredo Castello, Louisa Iselin

Subcell Biochem· January 2024

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Differences in proteome perturbations caused by the Wolbachia strain wAu suggest multiple mechanisms of Wolbachia-mediated antiviral activity.
Stephanie M Rainey, Vincent Geoghegan, Daniella A Lefteri, Thomas H Ant, Julien Martinez, Alfredo Castello

Sci Rep· July 2023

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Melanoma RBPome identification reveals PDIA6 as an unconventional RNA-binding protein involved in metastasis.
Neus Mestre-Farràs, Santiago Guerrero, Nadine Bley, Ezequiel Rivero, Olga Coll, Alfredo Castello

Nucleic Acids Res· August 2022

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RNA-binding protein Mub1 and the nuclear RNA exosome act to fine-tune environmental stress response.
Adrien Birot, Krzysztof Kus, Emily Priest, Ahmad Al Alwash, Alfredo Castello

Life Sci Alliance· February 2022

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Uncovering viral RNA-host cell interactions on a proteome-wide scale.
Louisa Iselin, Natasha Palmalux, Wael Kamel, Peter Simmonds, Shabaz Mohammed, Alfredo Castello

Trends Biochem Sci· January 2022

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Absolute quantitation of individual SARS-CoV-2 RNA molecules provides a new paradigm for infection dynamics and variant differences.
Jeffrey Y Lee, Peter A C Wing, Dalia S Gala, Marko Noerenberg, Aino I Järvelin, Alfredo Castello

Elife· January 2022

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A prenylated dsRNA sensor protects against severe COVID-19.
Arthur Wickenhagen, Elena Sugrue, Spyros Lytras, Srikeerthana Kuchi, Marko Noerenberg, Alfredo Castello

Science· October 2021

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The antiviral state has shaped the CpG composition of the vertebrate interferome to avoid self-targeting.
Andrew E Shaw, Suzannah J Rihn, Nardus Mollentze, Arthur Wickenhagen, Douglas G Stewart, Alfredo Castello

PLoS Biol· September 2021

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Global analysis of protein-RNA interactions in SARS-CoV-2-infected cells reveals key regulators of infection.
Wael Kamel, Marko Noerenberg, Berati Cerikan, Honglin Chen, Aino I Järvelin, Alfredo Castello

Mol Cell· July 2021

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Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells.
Peter A C Wing, Thomas P Keeley, Xiaodong Zhuang, Jeffrey Y Lee, Maria Prange-Barczynska, Alfredo Castello

Cell Rep· April 2021

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The importance of virion-incorporated cellular RNA-Binding Proteins in viral particle assembly and infectivity.
Kate Dicker, Aino I Järvelin, Manuel Garcia-Moreno, Alfredo Castello

Semin Cell Dev Biol· March 2021

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Global analysis of RNA-binding protein dynamics by comparative and enhanced RNA interactome capture.
Joel I Perez-Perri, Marko Noerenberg, Wael Kamel, Caroline E Lenz, Shabaz Mohammed, Alfredo Castello

Nat Protoc· January 2021

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HIV Rev-isited.
Catherine Toni-Sue Truman, Aino Järvelin, Ilan Davis, Alfredo Castello

Open Biol· December 2020

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CryoSIM: super-resolution 3D structured illumination cryogenic fluorescence microscopy for correlated ultrastructural imaging.
Michael A Phillips, Maria Harkiolaki, David Miguel Susano Pinto, Richard M Parton, Ana Palanca, Alfredo Castello

Optica· July 2020

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