Publications by authors named "Alice McDonald"

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KT-253, a Novel MDM2 Degrader and p53 Stabilizer, Has Superior Potency and Efficacy than MDM2 Small-Molecule Inhibitors.
Yogesh K Chutake, Michele F Mayo, Nancy Dumont, Jessica Filiatrault, Susanne B Breitkopf, Alice A McDonald

Mol Cancer Ther· April 2025

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Pharmacokinetics and Pharmacodynamics of KT-474, a Novel Selective Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) Degrader, in Healthy Adults.
Sagar Agarwal, Alice A McDonald, Veronica Campbell, Dapeng Chen, Jeff Davis

Clin Transl Sci· March 2025

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IRAK4 Is Overexpressed in Hidradenitis Suppurativa Skin and Correlates with Inflammatory Biomarkers.
Alice McDonald, Rahul Karnik, Veronica Campbell, Jeff Davis, Sara Chavoshi

J Invest Dermatol· February 2025

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Discovery of KT-474─a Potent, Selective, and Orally Bioavailable IRAK4 Degrader for the Treatment of Autoimmune Diseases.
Xiaozhang Zheng, Nan Ji, Veronica Campbell, Anthony Slavin, Xiao Zhu, Alice A McDonald

J Med Chem· October 2024

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Discovery of KT-413, a Targeted Protein Degrader of IRAK4 and IMiD Substrates Targeting MYD88 Mutant Diffuse Large B-Cell Lymphoma.
Matthew M Weiss, Xiaozhang Zheng, Nan Ji, Chris M Browne, Veronica Campbell, Alice A McDonald

J Med Chem· July 2024

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IRAK4 degrader in hidradenitis suppurativa and atopic dermatitis: a phase 1 trial.
Lindsay Ackerman, Gerard Acloque, Sandro Bacchelli, Howard Schwartz, Brian J Feinstein, Alice McDonald

Nat Med· December 2023

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Resource allocation in transboundary tuna fisheries: A global analysis.
Katherine Seto, Grantly R Galland, Alice McDonald, Angela Abolhassani, Kamal Azmi

Ambio· January 2021

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Cardiovascular Telemedicine Program in Rural Australia.
Adam C Scott, Alice McDonald, Tiffany Roberts, Curtis Martin, Timothy Manns

N Engl J Med· August 2020

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Tazemetostat, an EZH2 inhibitor, in relapsed or refractory B-cell non-Hodgkin lymphoma and advanced solid tumours: a first-in-human, open-label, phase 1 study.
Antoine Italiano, Jean-Charles Soria, Maud Toulmonde, Jean-Marie Michot, Carlo Lucchesi, Alice A McDonald

Lancet Oncol· May 2018

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Two Models to Conduct Nonphysician-led Exercise Stress Testing in Low to Intermediate Risk Patients.
Adam Scott, Mark Whitman, Alice McDonald, Meghan Webster, Carly Jenkins

Crit Pathw Cardiol· March 2017

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Targeting the protein ubiquitination machinery in melanoma by the NEDD8-activating enzyme inhibitor pevonedistat (MLN4924).
Kit Man Wong, Lindsey N Micel, Heather M Selby, Aik Choon Tan, Todd M Pitts, Alice McDonald

Invest New Drugs· February 2017

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The binocular advantage in visuomotor tasks involving tools.
Jenny C A Read, Shah Farzana Begum, Alice McDonald, Jack Trowbridge

Iperception· June 2013

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Tissue microarray analysis reveals protein expression patterns and potential biomarkers of clinical benefit to bortezomib in relapsed/refractory non-Hodgkin lymphoma.
John Gerecitano, Sivaraman Gounder, Julie Teruya-Feldstein, Maria Arcila, Shahiba Ogilvie, Alice McDonald

Br J Haematol· July 2012

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Treatment-emergent mutations in NAEβ confer resistance to the NEDD8-activating enzyme inhibitor MLN4924.
Michael A Milhollen, Michael P Thomas, Usha Narayanan, Tary Traore, Jessica Riceberg, Alice A McDonald

Cancer Cell· March 2012

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Potential biomarkers of bortezomib activity in mantle cell lymphoma from the phase 2 PINNACLE trial.
André Goy, Steven H Bernstein, Alice McDonald, Michael D Pickard, Hongliang Shi

Leuk Lymphoma· July 2010

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MLN8054, an inhibitor of Aurora A kinase, induces senescence in human tumor cells both in vitro and in vivo.
Jessica J Huck, Mengkun Zhang, Alice McDonald, Doug Bowman, Kara M Hoar

Mol Cancer Res· March 2010

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An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer.
Teresa A Soucy, Peter G Smith, Michael A Milhollen, Allison J Berger, James M Gavin, Alice McDonald

Nature· April 2009

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CCR8 expression identifies CD4 memory T cells enriched for FOXP3+ regulatory and Th2 effector lymphocytes.
Dulce Soler, Tobias R Chapman, Louis R Poisson, Lin Wang, Javier Cote-Sierra, Alice McDonald

J Immunol· November 2006

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The Steap proteins are metalloreductases.
Robert S Ohgami, Dean R Campagna, Alice McDonald, Mark D Fleming

Blood· August 2006

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The mitochondrial ATP-binding cassette transporter Abcb7 is essential in mice and participates in cytosolic iron-sulfur cluster biogenesis.
Corinne Pondarré, Brendan B Antiochos, Dean R Campagna, Stephen L Clarke, Eric L Greer, Alice McDonald

Hum Mol Genet· March 2006

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Modelling conservation in the Amazon basin.
Britaldo Silveira Soares-Filho, Daniel Curtis Nepstad, Lisa M Curran, Gustavo Coutinho Cerqueira, Ricardo Alexandrino Garcia, Alice McDonald

Nature· March 2006

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Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells.
Robert S Ohgami, Dean R Campagna, Eric L Greer, Brendan Antiochos, Alice McDonald

Nat Genet· November 2005

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A mammal-specific exon of WT1 is not required for development or fertility.
Thomas A Natoli, Alice McDonald, Julia A Alberta, Mary E Taglienti, David E Housman

Mol Cell Biol· June 2002

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