Publications by authors named "Alister Funnell"

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The glucocorticoid receptor elicited proliferative response in human erythropoiesis is BCL11A-dependent.
Maria Mazzarini, Jennifer Cherone, Truong Nguyen, Fabrizio Martelli, Lilian Varricchio, Alister P W Funnell

Stem Cells· November 2024

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The glucocorticoid receptor elicited proliferative response in human erythropoiesis is BCL11A-dependent.
Maria Mazzarini, Jennifer Cherone, Truong Nguyen, Fabrizio Martelli, Lilian Varricchio, Alister P W Funnell

bioRxiv· February 2024

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Patients with hypercortisolemic Cushing disease possess a distinct class of hematopoietic progenitor cells leading to erythrocytosis.
Lilian Varricchio, Eliza B Geer, Fabrizio Martelli, Maria Mazzarini, Alister Funnell

Haematologica· April 2023

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Elimination of fluorescent protein immunogenicity permits modeling of metastasis in immune-competent settings.
Candice A Grzelak, Erica T Goddard, Emma E Lederer, Kamya Rajaram, Jinxiang Dai, Alister P W Funnell

Cancer Cell· January 2022

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Enhanced HbF reactivation by multiplex mutagenesis of thalassemic CD34+ cells in vitro and in vivo.
Nikoletta Psatha, Aphrodite Georgakopoulou, Chang Li, Vivek Nandakumar, Grigorios Georgolopoulos, Alister Peter William Funnell

Blood· October 2021

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Global Regulatory DNA Potentiation by SMARCA4 Propagates to Selective Gene Expression Programs via Domain-Level Remodeling.
John E Lazar, Sandra Stehling-Sun, Vivek Nandakumar, Hao Wang, Daniel R Chee, Alister P W Funnell

Cell Rep· June 2020

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Global Regulatory DNA Potentiation by SMARCA4 Propagates to Selective Gene Expression Programs via Domain-Level Remodeling.
John E Lazar, Sandra Stehling-Sun, Vivek Nandakumar, Hao Wang, Daniel R Chee, Alister P W Funnell

Cell Rep· May 2020

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Hit and Run Transcriptional Repressors Are Difficult to Catch in the Act.
Manan Shah, Alister P W Funnell, Kate G R Quinlan, Merlin Crossley

Bioessays· August 2019

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Wake-up Sleepy Gene: Reactivating Fetal Globin for β-Hemoglobinopathies.
Beeke Wienert, Gabriella E Martyn, Alister P W Funnell, Kate G R Quinlan, Merlin Crossley

Trends Genet· December 2018

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Partial reprogramming of heterologous cells by defined factors to generate megakaryocyte lineage-restricted biomolecules.
Crisbel M Artuz, Alexander J Knights, Alister P W Funnell, Thomas J Gonda, Katya Ravid

Biotechnol Rep (Amst)· December 2018

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Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding.
Gabriella E Martyn, Beeke Wienert, Lu Yang, Manan Shah, Laura J Norton, Alister P W Funnell

Nat Genet· April 2018

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Corrigendum: Positively selected enhancer elements endow osteosarcoma cells with metastatic competence.
James J Morrow, Ian Bayles, Alister P W Funnell, Tyler E Miller, Alina Saiakhova

Nat Med· April 2018

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Positively selected enhancer elements endow osteosarcoma cells with metastatic competence.
James J Morrow, Ian Bayles, Alister P W Funnell, Tyler E Miller, Alina Saiakhova

Nat Med· February 2018

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Direct competition between DNA binding factors highlights the role of Krüppel-like Factor 1 in the erythroid/megakaryocyte switch.
Laura J Norton, Samantha Hallal, Elizabeth S Stout, Alister P W Funnell, Richard C M Pearson

Sci Rep· June 2017

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KLF1 directly activates expression of the novel fetal globin repressor in erythroid cells.
Laura J Norton, Alister P W Funnell, Jon Burdach, Beeke Wienert, Ryo Kurita

Blood Adv· April 2017

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Krüppel-like Factor 3 (KLF3/BKLF) Is Required for Widespread Repression of the Inflammatory Modulator Galectin-3 (Lgals3).
Alexander J Knights, Jinfen J Yik, Hanapi Mat Jusoh, Laura J Norton, Alister P W Funnell

J Biol Chem· July 2016

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Erratum to: Repression of chimeric transcripts emanating from endogenous retrotransposons by a sequence-specific transcription factor.
Ka Sin Mak, Jon Burdach, Laura J Norton, Richard Cm Pearson, Merlin Crossley, Alister Pw Funnell

Genome Biol· June 2016

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Directing an artificial zinc finger protein to new targets by fusion to a non-DNA-binding domain.
Wooi F Lim, Jon Burdach, Alister P W Funnell, Richard C M Pearson, Kate G R Quinlan

Nucleic Acids Res· April 2016

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Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin.
Takeshi Masuda, Xin Wang, Manami Maeda, Matthew C Canver, Falak Sher, Alister P W Funnell

Science· January 2016

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2p15-p16.1 microdeletions encompassing and proximal to BCL11A are associated with elevated HbF in addition to neurologic impairment.
Alister P W Funnell, Paolo Prontera, Valentina Ottaviani, Maria Piccione, Antonino Giambona

Blood· July 2015

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Editing the genome to introduce a beneficial naturally occurring mutation associated with increased fetal globin.
Beeke Wienert, Alister P W Funnell, Laura J Norton, Richard C M Pearson, Lorna E Wilkinson-White

Nat Commun· May 2015

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Phosphorylation of Krüppel-like factor 3 (KLF3/BKLF) and C-terminal binding protein 2 (CtBP2) by homeodomain-interacting protein kinase 2 (HIPK2) modulates KLF3 DNA binding and activity.
Vitri Dewi, Alister Kwok, Stella Lee, Ming Min Lee, Yee Mun Tan, Alister P W Funnell

J Biol Chem· March 2015

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Multi-species, multi-transcription factor binding highlights conserved control of tissue-specific biological pathways.
Benoit Ballester, Alejandra Medina-Rivera, Dominic Schmidt, Mar Gonzàlez-Porta, Matthew Carlucci, Alister P W Funnell

Elife· October 2014

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Differential regulation of the α-globin locus by Krüppel-like Factor 3 in erythroid and non-erythroid cells.
Alister P W Funnell, Douglas Vernimmen, Wooi F Lim, Ka Sin Mak, Beeke Wienert

BMC Mol Biol· May 2014

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Repression of chimeric transcripts emanating from endogenous retrotransposons by a sequence-specific transcription factor.
Ka Sin Mak, Jon Burdach, Laura J Norton, Richard C M Pearson, Merlin Crossley, Alister P W Funnell

Genome Biol· April 2014

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