Publications by authors named "Allen A Thomas"

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H
Hydantion indolinones as AANAT inhibitors.
Nicole Wandrey, Jake Boley, Dirce Gómez-Galicia, Mackinzi Hill, Mason Bach, Allen A Thomas

Bioorg Med Chem Lett· February 2026

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Human citrate synthase kinetic simulation to fit rapid, direct, and thiol probe coupled kinetic data.
Noah Shackelford, Zach Zavodny, Samantha Schindler, Nathan Fancher, Allen A Thomas

Biochem Biophys Rep· March 2025

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AANAT kinetics of CoASH-targeted electrophiles of tryptamine and related analogs.
Nicole Wandrey, Luke Hamilton, Jake Boley, Alexis Haynes, Makenna Redinger, Allen A Thomas

Bioorg Med Chem Lett· November 2024

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Evaluation of Rhodanine Indolinones as AANAT Inhibitors.
Mackenzie Hagemeister, Luke Hamilton, Nicole Wandrey, Mackinzi Hill, Emery Mounce, Allen A Thomas

ChemMedChem· January 2024

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Synthesis of ribavirin 1,2,3- and 1,2,4-triazolyl analogs with changes at the amide and cytotoxicity in breast cancer cell lines.
Hannah Way, Joshua Roh, Brooklynn Venteicher, Surabhi Chandra, Allen A Thomas

Nucleosides Nucleotides Nucleic Acids· February 2023

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Describing inhibitor specificity for the amino acid transporter LAT1 from metainference simulations.
Keino Hutchinson, Dina Buitrago Silva, Joshua Bohlke, Chase Clausen, Allen A Thomas

Biophys J· December 2022

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The Effects of Prodrug Size and a Carbonyl Linker on l-Type Amino Acid Transporter 1-Targeted Cellular and Brain Uptake.
Brooklynn Venteicher, Kasey Merklin, Huy X Ngo, Huan-Chieh Chien, Keino Hutchinson, Allen A Thomas

ChemMedChem· March 2021

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l-Type amino acid transporter 1 activity of 1,2,3-triazolyl analogs of l-histidine and l-tryptophan.
Colton Hall, Hannah Wolfe, Alyssa Wells, Huan-Chieh Chien, Claire Colas, Allen A Thomas

Bioorg Med Chem Lett· August 2019

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Cellular fatty acid level regulates the effect of tolylfluanid on mitochondrial dysfunction and insulin sensitivity in C2C12 skeletal myotubes.
A'Lexxus F Davis, Allen A Thomas, Kimberly S Shorter, Stephan L Brown, Bradley L Baumgarner

Biochem Biophys Res Commun· October 2018

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Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1).
Huan-Chieh Chien, Claire Colas, Karissa Finke, Seth Springer, Laura Stoner, Allen A Thomas

J Med Chem· August 2018

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LAT1 activity of carboxylic acid bioisosteres: Evaluation of hydroxamic acids as substrates.
Arik A Zur, Huan-Chieh Chien, Evan Augustyn, Andrew Flint, Nathan Heeren, Allen A Thomas

Bioorg Med Chem Lett· October 2016

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LAT-1 activity of meta-substituted phenylalanine and tyrosine analogs.
Evan Augustyn, Karissa Finke, Arik A Zur, Logan Hansen, Nathan Heeren, Allen A Thomas

Bioorg Med Chem Lett· June 2016

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8-Tetrahydropyran-2-yl chromans: highly selective beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors.
Allen A Thomas, Kevin W Hunt, Brad Newhouse, Ryan J Watts, Xingrong Liu

J Med Chem· December 2014

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Synthesis, characterization, and PK/PD studies of a series of spirocyclic pyranochromene BACE1 inhibitors.
Matthew Volgraf, Lina Chan, Malcolm P Huestis, Hans E Purkey, Michael Burkard, Allen A Thomas

Bioorg Med Chem Lett· June 2014

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Discovery of 7-tetrahydropyran-2-yl chromans: β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors that reduce amyloid β-protein (Aβ) in the central nervous system.
Allen A Thomas, Kevin W Hunt, Matthew Volgraf, Ryan J Watts, Xingrong Liu

J Med Chem· February 2014

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Mechanistic pharmacokinetic-pharmacodynamic modeling of BACE1 inhibition in monkeys: development of a predictive model for amyloid precursor protein processing.
Xingrong Liu, Harvey Wong, Kimberly Scearce-Levie, Ryan J Watts, Melis Coraggio, Allen A Thomas

Drug Metab Dispos· July 2013

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Spirocyclic β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors: from hit to lowering of cerebrospinal fluid (CSF) amyloid β in a higher species.
Kevin W Hunt, Adam W Cook, Ryan J Watts, Christopher T Clark, Guy Vigers, Allen A Thomas

J Med Chem· April 2013

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Synthesis, in vitro and in vivo activity of thiamine antagonist transketolase inhibitors.
Allen A Thomas, Y Le Huerou, J De Meese, Indrani Gunawardana, Tomas Kaplan

Bioorg Med Chem Lett· March 2008

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Prodrug thiamine analogs as inhibitors of the enzyme transketolase.
Yvan Le Huerou, Indrani Gunawardana, Allen A Thomas, Steven A Boyd, Jason de Meese

Bioorg Med Chem Lett· January 2008

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Non-charged thiamine analogs as inhibitors of enzyme transketolase.
Allen A Thomas, J De Meese, Y Le Huerou, Steven A Boyd, Todd T Romoff, Thomas D Aicher

Bioorg Med Chem Lett· January 2008

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The Catalytic Asymmetric Aminohydroxylation of Unsaturated Phosphonates.
Allen A. Thomas, K. Barry Sharpless

J Org Chem· October 1999

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