Publications by authors named "Amy M Pooler"

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Persistent repression of tau in the brain using engineered zinc finger protein transcription factors.
Susanne Wegmann, Sarah L DeVos, Bryan Zeitler, Kimberly Marlen, Rachel E Bennett, Amy M Pooler

Sci Adv· March 2021

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Apolipoprotein E4 Expression Causes Gain of Toxic Function in Isogenic Human Induced Pluripotent Stem Cell-Derived Endothelial Cells.
Claus Rieker, Eugenia Migliavacca, Angélique Vaucher, Gilles Baud, Julien Marquis, Amy M Pooler

Arterioscler Thromb Vasc Biol· September 2019

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Progressive Neuronal Pathology and Synaptic Loss Induced by Prediabetes and Type 2 Diabetes in a Mouse Model of Alzheimer's Disease.
Juan Jose Ramos-Rodriguez, Tara Spires-Jones, Amy M Pooler, Alfonso Maria Lechuga-Sancho, Brian J Bacskai

Mol Neurobiol· July 2017

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Membrane association and release of wild-type and pathological tau from organotypic brain slice cultures.
Cara L Croft, Matthew A Wade, Ksenia Kurbatskaya, Pavlina Mastrandreas, Martina M Hughes, Amy M Pooler

Cell Death Dis· March 2017

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A systems approach to personalised nutrition: Report on the Keystone Symposium "Human Nutrition, Environment and Health".
Michael Maher, Amy M Pooler, James Kaput, Martin Kussmann

Appl Transl Genom· September 2016

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Critical residues involved in tau binding to fyn: implications for tau phosphorylation in Alzheimer's disease.
Dawn H W Lau, Marte Hogseth, Emma C Phillips, Michael J O'Neill, Amy M Pooler

Acta Neuropathol Commun· May 2016

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Mislocalization of neuronal tau in the absence of tangle pathology in phosphomutant tau knockin mice.
Jonathan Gilley, Kunie Ando, Anjan Seereeram, Teresa Rodríguez-Martín, Amy M Pooler

Neurobiol Aging· March 2016

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Reduced number of axonal mitochondria and tau hypophosphorylation in mouse P301L tau knockin neurons.
Teresa Rodríguez-Martín, Amy M Pooler, Dawn H W Lau, Gábor M Mórotz, Kurt J De Vos

Neurobiol Dis· January 2016

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Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity.
Susanne Wegmann, Eduardo A Maury, Molly J Kirk, Lubna Saqran, Allyson Roe, Amy M Pooler

EMBO J· December 2015

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Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer's disease.
Amy M Pooler, Manuela Polydoro, Eduardo A Maury, Samantha B Nicholls, Snigdha M Reddy

Acta Neuropathol Commun· March 2015

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Intracellular and extracellular roles for tau in neurodegenerative disease.
Diane P Hanger, Dawn H W Lau, Emma C Phillips, Marie K Bondulich, Tong Guo, Amy M Pooler

J Alzheimers Dis· January 2015

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Propagation of tau pathology in Alzheimer's disease: identification of novel therapeutic targets.
Amy M Pooler, Manuela Polydoro, Susanne Wegmann, Samantha B Nicholls, Tara L Spires-Jones

Alzheimers Res Ther· June 2014

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Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer's disease model.
Manuela Polydoro, Volodymyr I Dzhala, Amy M Pooler, Samantha B Nicholls, A Patrick McKinney

Acta Neuropathol· February 2014

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Studying synapses in human brain with array tomography and electron microscopy.
Kevin R Kay, Colin Smith, Ann K Wright, Alberto Serrano-Pozo, Amy M Pooler

Nat Protoc· January 2014

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A role for tau at the synapse in Alzheimer's disease pathogenesis.
Amy M Pooler, Wendy Noble, Diane P Hanger

Neuropharmacology· January 2014

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Tau-amyloid interactions in the rTgTauEC model of early Alzheimer's disease suggest amyloid-induced disruption of axonal projections and exacerbated axonal pathology.
Amy M Pooler, Manuela Polydoro, Susanne K Wegmann, Rose Pitstick, Kevin R Kay

J Comp Neurol· December 2013

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Physiological release of endogenous tau is stimulated by neuronal activity.
Amy M Pooler, Emma C Phillips, Dawn H W Lau, Wendy Noble, Diane P Hanger

EMBO Rep· April 2013

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NUB1 modulation of GSK3β reduces tau aggregation.
Emma Richet, Amy M Pooler, Teresa Rodriguez, Sergey S Novoselov, Gunter Schmidtke

Hum Mol Genet· December 2012

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Dynamic association of tau with neuronal membranes is regulated by phosphorylation.
Amy M Pooler, Alessia Usardi, Catherine J Evans, Karen L Philpott, Wendy Noble

Neurobiol Aging· February 2012

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Tyrosine phosphorylation of tau regulates its interactions with Fyn SH2 domains, but not SH3 domains, altering the cellular localization of tau.
Alessia Usardi, Amy M Pooler, Anjan Seereeram, C Hugh Reynolds, Pascal Derkinderen

FEBS J· August 2011

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Advances in tau-based drug discovery.
Wendy Noble, Amy M Pooler, Diane P Hanger

Expert Opin Drug Discov· August 2011

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Copines-1, -2, -3, -6 and -7 show different calcium-dependent intracellular membrane translocation and targeting.
Pavel V Perestenko, Amy M Pooler, Maryam Noorbakhshnia, Adrian Gray, Charlotte Bauccio

FEBS J· December 2010

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Functional implications of the association of tau with the plasma membrane.
Amy M Pooler, Diane P Hanger

Biochem Soc Trans· August 2010

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Lateral diffusion of the GABAB receptor is regulated by the GABAB2 C terminus.
Amy M Pooler, R A Jeffrey McIlhinney

J Biol Chem· August 2007

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The 3-hydroxy-3-methylglutaryl co-enzyme A reductase inhibitor pravastatin enhances neurite outgrowth in hippocampal neurons.
Amy M Pooler, Shijun C Xi, Richard J Wurtman

J Neurochem· May 2006

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