Publications by authors named "Rose Pitstick"

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Therapeutic Trial of anle138b in Mouse Models of Genetic Prion Disease.
Sonia M Vallabh, Dan Zou, Rose Pitstick, Jill O'Moore, Janet Peters

J Virol· February 2023

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Leucine Carboxyl Methyltransferase 1 Overexpression Protects Against Cognitive and Electrophysiological Impairments in Tg2576 APP Transgenic Mice.
Madhumathi Gnanaprakash, Agnieszka Staniszewski, Hong Zhang, Rose Pitstick, Michael P Kavanaugh

J Alzheimers Dis· September 2021

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Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints.
Eric Vallabh Minikel, Hien T Zhao, Jason Le, Jill O'Moore, Rose Pitstick

Nucleic Acids Res· November 2020

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Reduced Expression of the PP2A Methylesterase, PME-1, or the PP2A Methyltransferase, LCMT-1, Alters Sensitivity to Beta-Amyloid-Induced Cognitive and Electrophysiological Impairments in Mice.
Agnieszka Staniszewski, Hong Zhang, Kesava Asam, Rose Pitstick, Michael P Kavanaugh

J Neurosci· June 2020

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Tau reduction in the presence of amyloid-β prevents tau pathology and neuronal death in vivo.
Sarah L DeVos, Bianca T Corjuc, Caitlin Commins, Simon Dujardin, Riley N Bannon, Rose Pitstick

Brain· July 2018

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Improvement of ENU Mutagenesis Efficiency Using Serial Injection and Mismatch Repair Deficiency Mice.
Jabier Gallego-Llamas, Andrew E Timms, Rose Pitstick, Janet Peters, George A Carlson

PLoS One· July 2017

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Enhanced Tau Aggregation in the Presence of Amyloid β.
Rachel E Bennett, Sarah L DeVos, Simon Dujardin, Bianca Corjuc, Rucha Gor, Rose Pitstick

Am J Pathol· July 2017

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Spread of tau down neural circuits precedes synapse and neuronal loss in the rTgTauEC mouse model of early Alzheimer's disease.
Eleanor K Pickett, Christopher M Henstridge, Elizabeth Allison, Rose Pitstick, Amy Pooler

Synapse· June 2017

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Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro.
Chloe K Nobuhara, Sarah L DeVos, Caitlin Commins, Susanne Wegmann, Benjamin D Moore, Rose Pitstick

Am J Pathol· June 2017

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Human tau increases amyloid β plaque size but not amyloid β-mediated synapse loss in a novel mouse model of Alzheimer's disease.
Rosemary J Jackson, Nikita Rudinskiy, Abigail G Herrmann, Shaun Croft, JeeSoo Monica Kim, Rose Pitstick

Eur J Neurosci· December 2016

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Seed-competent high-molecular-weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients.
Shuko Takeda, Caitlin Commins, Sarah L DeVos, Chloe K Nobuhara, Susanne Wegmann, Rose Pitstick

Ann Neurol· September 2016

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Reduction of ciliary length through pharmacologic or genetic inhibition of CDK5 attenuates polycystic kidney disease in a model of nephronophthisis.
Hervé Husson, Sarah Moreno, Laurie A Smith, Mandy M Smith, Ryan J Russo, Rose Pitstick

Hum Mol Genet· June 2016

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Brain Aggregates: An Effective In Vitro Cell Culture System Modeling Neurodegenerative Diseases.
Misol Ahn, Franck Kalume, Rose Pitstick, Abby Oehler, George Carlson

J Neuropathol Exp Neurol· March 2016

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Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity.
Susanne Wegmann, Eduardo A Maury, Molly J Kirk, Lubna Saqran, Allyson Roe, Rose Pitstick

EMBO J· December 2015

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Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer's disease brain.
Shuko Takeda, Susanne Wegmann, Hansang Cho, Sarah L DeVos, Caitlin Commins, Rose Pitstick

Nat Commun· October 2015

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Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer's disease.
Amy M Pooler, Manuela Polydoro, Eduardo A Maury, Samantha B Nicholls, Snigdha M Reddy, Rose Pitstick

Acta Neuropathol Commun· March 2015

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Tau causes synapse loss without disrupting calcium homeostasis in the rTg4510 model of tauopathy.
Katherine J Kopeikina, Susanne Wegmann, Rose Pitstick, George A Carlson, Brian J Bacskai

PLoS One· December 2014

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Methylene blue does not reverse existing neurofibrillary tangle pathology in the rTg4510 mouse model of tauopathy.
Tara L Spires-Jones, Taylor Friedman, Rose Pitstick, Manuela Polydoro, Allyson Roe

Neurosci Lett· March 2014

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Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer's disease model.
Manuela Polydoro, Volodymyr I Dzhala, Amy M Pooler, Samantha B Nicholls, A Patrick McKinney, Rose Pitstick

Acta Neuropathol· February 2014

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Tau-amyloid interactions in the rTgTauEC model of early Alzheimer's disease suggest amyloid-induced disruption of axonal projections and exacerbated axonal pathology.
Amy M Pooler, Manuela Polydoro, Susanne K Wegmann, Rose Pitstick, Kevin R Kay

J Comp Neurol· December 2013

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Reversal of neurofibrillary tangles and tau-associated phenotype in the rTgTauEC model of early Alzheimer's disease.
Manuela Polydoro, Alix de Calignon, Marc Suárez-Calvet, Laura Sanchez, Kevin R Kay, Rose Pitstick

J Neurosci· August 2013

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Levels of the Mahogunin Ring Finger 1 E3 ubiquitin ligase do not influence prion disease.
Derek Silvius, Rose Pitstick, Misol Ahn, Delisha Meishery, Abby Oehler

PLoS One· July 2013

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Synaptic alterations in the rTg4510 mouse model of tauopathy.
Katherine J Kopeikina, Manuela Polydoro, Hwan-Ching Tai, Erich Yaeger, George A Carlson, Rose Pitstick

J Comp Neurol· April 2013

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Genotype-specific differences between mouse CNS stem cell lines expressing frontotemporal dementia mutant or wild type human tau.
Miranda E Orr, Rose Pitstick, Brenda Canine, Karen H Ashe, George A Carlson

PLoS One· December 2012

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Knockout of the prion protein (PrP)-like Sprn gene does not produce embryonic lethality in combination with PrP(C)-deficiency.
Nathalie Daude, Serene Wohlgemuth, Rebecca Brown, Rose Pitstick, Hristina Gapeshina

Proc Natl Acad Sci U S A· June 2012

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