Publications by authors named "George Carlson"

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Severe neurodegeneration in brains of transgenic rats producing human tau prions.
Jacob Ayers, T Peter Lopez, Ian T Steele, Abby Oehler, Rigo Roman-Albarran, George A Carlson

Acta Neuropathol· August 2024

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Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.
Tagan A Griffin, Paul D Schnier, Elisa M Cleveland, Robert W Newberry, Julia Becker, George A Carlson

J Biol Chem· March 2023

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Therapeutic Trial of anle138b in Mouse Models of Genetic Prion Disease.
Sonia M Vallabh, Dan Zou, Rose Pitstick, Jill O'Moore, Janet Peters, George A Carlson

J Virol· February 2023

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Tau aggregates are RNA-protein assemblies that mislocalize multiple nuclear speckle components.
Evan Lester, Felicia K Ooi, Nadine Bakkar, Jacob Ayers, Amanda L Woerman, George A Carlson

Neuron· May 2021

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How an Infection of Sheep Revealed Prion Mechanisms in Alzheimer's Disease and Other Neurodegenerative Disorders.
George A Carlson, Stanley B Prusiner

Int J Mol Sci· May 2021

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Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints.
Eric Vallabh Minikel, Hien T Zhao, Jason Le, Jill O'Moore, Rose Pitstick, George A Carlson

Nucleic Acids Res· November 2020

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Core transcriptional regulatory circuits in prion diseases.
Taek-Kyun Kim, Inyoul Lee, Ji-Hoon Cho, Brenda Canine, Andrew Keller, George Carlson

Mol Brain· January 2020

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Replication of multiple system atrophy prions in primary astrocyte cultures from transgenic mice expressing human α-synuclein.
Zuzana Krejciova, George A Carlson, Kurt Giles, Stanley B Prusiner

Acta Neuropathol Commun· May 2019

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Tau impairs neural circuits, dominating amyloid-β effects, in Alzheimer models in vivo.
Marc Aurel Busche, Susanne Wegmann, Simon Dujardin, Caitlin Commins, Julia Schiantarelli, George A Carlson

Nat Neurosci· January 2019

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Tau reduction in the presence of amyloid-β prevents tau pathology and neuronal death in vivo.
Sarah L DeVos, Bianca T Corjuc, Caitlin Commins, Simon Dujardin, Riley N Bannon, George A Carlson

Brain· July 2018

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Prion Protein and Genetic Susceptibility to Diseases Caused by Its Misfolding.
George A Carlson

Prog Mol Biol Transl Sci· May 2018

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Evidence for sortilin modulating regional accumulation of human tau prions in transgenic mice.
Noah R Johnson, Carlo Condello, Shenheng Guan, Abby Oehler, Julia Becker, George A Carlson

Proc Natl Acad Sci U S A· December 2017

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Neurodegenerative Disease Transmission and Transgenesis in Mice.
Brittany N Dugger, Daniel P Perl, George A Carlson

Cold Spring Harb Perspect Biol· November 2017

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A novel vector for transgenesis in the rat CNS.
T Peter Lopez, Kurt Giles, Brittany N Dugger, Abby Oehler, Carlo Condello, George A Carlson

Acta Neuropathol Commun· November 2017

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Improvement of ENU Mutagenesis Efficiency Using Serial Injection and Mismatch Repair Deficiency Mice.
Jabier Gallego-Llamas, Andrew E Timms, Rose Pitstick, Janet Peters, George A Carlson

PLoS One· July 2017

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Postnatal Hyperplasic Effects of ActRIIB Blockade in a Severely Dystrophic Muscle.
Cory Nielsen, Ross M Potter, Christopher Borowy, Kimberly Jacinto, Ravi Kumar, C George Carlson

J Cell Physiol· July 2017

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Enhanced Tau Aggregation in the Presence of Amyloid β.
Rachel E Bennett, Sarah L DeVos, Simon Dujardin, Bianca Corjuc, Rucha Gor, George A Carlson

Am J Pathol· July 2017

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Brain Perivascular Macrophages Initiate the Neurovascular Dysfunction of Alzheimer Aβ Peptides.
Laibaik Park, Ken Uekawa, Lidia Garcia-Bonilla, Kenzo Koizumi, Michelle Murphy, George Carlson

Circ Res· July 2017

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Spread of tau down neural circuits precedes synapse and neuronal loss in the rTgTauEC mouse model of early Alzheimer's disease.
Eleanor K Pickett, Christopher M Henstridge, Elizabeth Allison, Rose Pitstick, Amy Pooler, George Carlson

Synapse· June 2017

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Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro.
Chloe K Nobuhara, Sarah L DeVos, Caitlin Commins, Susanne Wegmann, Benjamin D Moore, George A Carlson

Am J Pathol· June 2017

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The familial dysautonomia disease gene is required in the developing and adult mouse central nervous system.
Marta Chaverra, Lynn George, Marc Mergy, Hannah Waller, Katharine Kujawa, George A Carlson

Dis Model Mech· May 2017

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High resolution time-course mapping of early transcriptomic, molecular and cellular phenotypes in Huntington's disease CAG knock-in mice across multiple genetic backgrounds.
Seth A Ament, Jocelynn R Pearl, Andrea Grindeland, Jason St Claire, John C Earls, George Carlson

Hum Mol Genet· March 2017

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Human tau increases amyloid β plaque size but not amyloid β-mediated synapse loss in a novel mouse model of Alzheimer's disease.
Rosemary J Jackson, Nikita Rudinskiy, Abigail G Herrmann, Shaun Croft, JeeSoo Monica Kim, George A Carlson

Eur J Neurosci· December 2016

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Stabilizing the Hsp70-Tau Complex Promotes Turnover in Models of Tauopathy.
Zapporah T Young, Jennifer N Rauch, Victoria A Assimon, Umesh K Jinwal, Misol Ahn, George A Carlson

Cell Chem Biol· August 2016

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Reduction of ciliary length through pharmacologic or genetic inhibition of CDK5 attenuates polycystic kidney disease in a model of nephronophthisis.
Hervé Husson, Sarah Moreno, Laurie A Smith, Mandy M Smith, Ryan J Russo, George Carlson

Hum Mol Genet· June 2016

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