Publications by authors named "Andrew Carnell"

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Development of the Esterase PestE for Amide Bond Synthesis Under Aqueous Conditions: Enzyme Cascades for Converting Waste PET into Tamibarotene.
Ellie Goulding, Lucy C Ward, Faye E Allan, Drew Dittman, Jesus E Salcedo-Sora, Andrew J Carnell

Angew Chem Int Ed Engl· January 2025

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Rational design of a cyclohexanone dehydrogenase for enhanced α,β-desaturation and substrate specificity.
Warispreet Singh, Nicola L Brown, Hannah V McCue, Sophie R Marriott, Richard C Wilson, Andrew J Carnell

Chem Sci· March 2024

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Engineering a Carboxyl Methyltransferase for the Formation of a Furan-Based Bioplastic Precursor.
Lucy C Ward, Ellie Goulding, Daniel J Rigden, Faye E Allan, Alessandro Pellis, Andrew J Carnell

ChemSusChem· August 2023

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Targeted Destruction of S100A4 Inhibits Metastasis of Triple Negative Breast Cancer Cells.
Thamir M Ismail, Rachel G Crick, Min Du, Uma Shivkumar, Andrew Carnell

Biomolecules· July 2023

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Carboxyl Methyltransferase Catalysed Formation of Mono- and Dimethyl Esters under Aqueous Conditions: Application in Cascade Biocatalysis.
Lucy C Ward, Hannah V McCue, Daniel J Rigden, Neil M Kershaw, Chloe Ashbrook, Andrew J Carnell

Angew Chem Int Ed Engl· March 2022

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Real-Time Monitoring of Enzyme-Catalysed Reactions using Deep UV Resonance Raman Spectroscopy.
Chloe Westley, Heidi Fisk, Yun Xu, Katherine A Hollywood, Andrew J Carnell

Chemistry· May 2017

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Absolute Quantification of Uric Acid in Human Urine Using Surface Enhanced Raman Scattering with the Standard Addition Method.
Chloe Westley, Yun Xu, Baskaran Thilaganathan, Andrew J Carnell, Nicholas J Turner

Anal Chem· February 2017

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Label-Free Surface Enhanced Raman Scattering Approach for High-Throughput Screening of Biocatalysts.
Chloe Westley, Yun Xu, Andrew J Carnell, Nicholas J Turner, Royston Goodacre

Anal Chem· June 2016

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Trifluoroibuprofen inhibits α-methylacyl coenzyme A racemase (AMACR/P504S), reduces cancer cell proliferation and inhibits in vivo tumor growth in aggressive prostate cancer models.
Claudio Festuccia, Giovanni Luca Gravina, Andrea Mancini, Paola Muzi, Ernesto Di Cesare, Andrew J Carnell

Anticancer Agents Med Chem· June 2015

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Independently outgrowing neurons and geometry-based synapse formation produce networks with realistic synaptic connectivity.
Arjen van Ooyen, Andrew Carnell, Sander de Ridder, Bernadetta Tarigan, Huibert D Mansvelder

PLoS One· September 2014

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Glycosylated yellow laccases of the basidiomycete Stropharia aeruginosa.
Maurycy Daroch, Catharine A Houghton, Jonathan K Moore, Mark C Wilkinson, Andrew J Carnell

Enzyme Microb Technol· May 2014

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Inhibition of human α-methylacyl CoA racemase (AMACR): a target for prostate cancer.
Andrew J Carnell, Ralph Kirk, Matthew Smith, Shane McKenna, Lu-Yun Lian

ChemMedChem· October 2013

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Enantioselective rhodium-catalyzed addition of potassium alkenyltrifluoroborates to cyclic imines.
Yunfei Luo, Andrew J Carnell, Hon Wai Lam

Angew Chem Int Ed Engl· July 2012

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Chiral bicyclic [2.2.2] octadiene ligands for Rh-catalysed catalytic asymmetric conjugate additions to acyclic enones: a quantitative structure-property relationship.
Yunfei Luo, Neil G Berry, Andrew J Carnell

Chem Commun (Camb)· April 2012

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An algorithm for finding candidate synaptic sites in computer generated networks of neurons with realistic morphologies.
Jaap van Pelt, Andrew Carnell, Sander de Ridder, Huibert D Mansvelder, Arjen van Ooyen

Front Comput Neurosci· July 2011

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Chemoenzymatic synthesis and application of bicyclo[2.2.2]octadiene ligands: increased efficiency in rhodium-catalyzed asymmetric conjugate additions by electronic tuning.
Yunfei Luo, Andrew J Carnell

Angew Chem Int Ed Engl· April 2010

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A practical chemo-enzymatic synthesis of homochiral bicyclo[2.2.2]octane-2,5-dione.
Yunfei Luo, Andrew J Carnell

J Org Chem· March 2010

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Design, synthesis, and in vitro testing of alpha-methylacyl-CoA racemase inhibitors.
Andrew J Carnell, Ian Hale, Simone Denis, Ronald J A Wanders, William B Isaacs

J Med Chem· May 2007

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A novel regiospecific N to O-methyl transferase activity in the biotransformation of a thebaine derivative with Cunninghamella echinulata NRRL 1384.
Anthony M Abel, Graham R Allan, Andrew J Carnell, J Alf Davis

Chem Commun (Camb)· August 2002

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Total Synthesis of (-)-Reserpine Using the Chiron Approach.
Stephen Hanessian, Jingwen Pan, Andrew Carnell, Hervé Bouchard, Luc Lesage

J Org Chem· February 1997

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