Publications by authors named "Andrew Howden"

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Author Correction: Hypoxia induces histone clipping and H3K4me3 loss in neutrophil progenitors resulting in long-term impairment of neutrophil immunity.
Manuel A Sanchez-Garcia, Pranvera Sadiku, Brian M Ortmann, Niek Wit, Yutaka Negishi, Andrew J M Howden

Nat Immunol· December 2025

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Single cell proteomic analysis defines discrete neutrophil functional states in human glioblastoma.
Pranvera Sadiku, Alejandro J Brenes, Rupert L Mayer, Leila Reyes, Patricia Coelho, Andrew J M Howden

Nat Commun· December 2025

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Hypoxia induces histone clipping and H3K4me3 loss in neutrophil progenitors resulting in long-term impairment of neutrophil immunity.
Manuel A Sanchez-Garcia, Pranvera Sadiku, Brian M Ortmann, Niek Wit, Yutaka Negishi, Andrew J M Howden

Nat Immunol· November 2025

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Inflammation and IL-4 regulate Parkinson's and Crohn's disease associated kinase LRRK2.
Dina Dikovskaya, Rebecca Pemberton, Matthew Taylor, Anna Tasegian, Purbasha Bhattacharya, Andrew J M Howden

EMBO Rep· July 2025

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A proteogenomic tool uncovers protein markers for human microglial states.
Verena Haage, Alex R Bautista, John Tuddenham, Victoria Marshe, Rebecca Chiu, Andrew J M Howden

bioRxiv· April 2025

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Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells.
Linda V Sinclair, Tom Youdale, Laura Spinelli, Milica Gakovic, Alistair J Langlands, Andrew J M Howden

Nat Immunol· March 2025

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Ancient genomic linkage of α-globin and Nprl3 couples metabolism with erythropoiesis.
Alexandra E Preston, Joe N Frost, Megan R Teh, Mohsin Badat, Andrew E Armitage, Andrew Jm Howden

Nat Commun· March 2025

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Synaptic signatures and disease vulnerabilities of layer 5 pyramidal neurons.
Gabriele Marcassa, Dan Dascenco, Blanca Lorente-Echeverría, Danie Daaboul, Jeroen Vandensteen, Andrew J M Howden

Nat Commun· January 2025

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Deep proteomic analysis of microglia reveals fundamental biological differences between model systems.
Amy F Lloyd, Anna Martinez-Muriana, Emma Davis, Michael J D Daniels, Pengfei Hou, Andrew J M Howden

Cell Rep· November 2024

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Extensive acute and sustained changes to neutrophil proteomes post-SARS-CoV-2 infection.
Merete B Long, Andrew J M Howden, Holly R Keir, Christina M Rollings, Yan Hui Giam

Eur Respir J· March 2024

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Quantitative proteomics reveals tissue-specific, infection-induced and species-specific neutrophil protein signatures.
Gabriel Sollberger, Alejandro J Brenes, Jordan Warner, J Simon C Arthur, Andrew J M Howden

Sci Rep· March 2024

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RNA helicase EIF4A1-mediated translation is essential for the GC response.
Michael Screen, Louise S Matheson, Andrew Jm Howden, Douglas Strathdee, Anne E Willis

Life Sci Alliance· February 2024

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The γ-secretase substrate proteome and its role in cell signaling regulation.
Pengfei Hou, Magdalena Zielonka, Lutgarde Serneels, Anna Martinez-Muriana, Nicola Fattorelli, Andrew J M Howden

Mol Cell· November 2023

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An integrated proteome and transcriptome of B cell maturation defines poised activation states of transitional and mature B cells.
Fiamma Salerno, Andrew J M Howden, Louise S Matheson, Özge Gizlenci, Michael Screen

Nat Commun· August 2023

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microRNA-132 regulates gene expression programs involved in microglial homeostasis.
Hannah Walgrave, Amber Penning, Giorgia Tosoni, Sarah Snoeck, Kristofer Davie, Andrew J M Howden

iScience· June 2023

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Astrocyte-oligodendrocyte interaction regulates central nervous system regeneration.
Irene Molina-Gonzalez, Rebecca K Holloway, Zoeb Jiwaji, Owen Dando, Sarah A Kent, Andrew J M Howden

Nat Commun· June 2023

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NRF2 Activation Reprograms Defects in Oxidative Metabolism to Restore Macrophage Function in Chronic Obstructive Pulmonary Disease.
Eilise M Ryan, Pranvera Sadiku, Patricia Coelho, Emily R Watts, Ailiang Zhang, Andrew J M Howden

Am J Respir Crit Care Med· April 2023

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Amino acid availability acts as a metabolic rheostat to determine the magnitude of ILC2 responses.
Suzanne H Hodge, Maria Z Krauss, Irem Kaymak, James I King, Andrew J M Howden

J Exp Med· March 2023

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AMPK integrates metabolite and kinase-based immunometabolic control in macrophages.
Iain R Phair, Raid B Nisr, Andrew J M Howden, Magdalena Sovakova, Noor Alqurashi

Mol Metab· February 2023

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DIA label-free proteomic analysis of murine bone-marrow-derived macrophages.
Christa P Baker, Iain R Phair, Alejandro J Brenes, Abdelmadjid Atrih, Dylan G Ryan, Andrew J M Howden

STAR Protoc· December 2022

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Hypoxia drives murine neutrophil protein scavenging to maintain central carbon metabolism.
Emily R Watts, Andrew Jm Howden, Tyler Morrison, Pranvera Sadiku, Jens Hukelmann

J Clin Invest· May 2021

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Extracellular signal-regulated kinase (ERK) pathway control of CD8+ T cell differentiation.
Marcos P Damasio, Julia M Marchingo, Laura Spinelli, Jens L Hukelmann, Doreen A Cantrell, Andrew J M Howden

Biochem J· January 2021

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Human Peripheral Blood Neutrophil Isolation for Interrogating the Parkinson's Associated LRRK2 Kinase Pathway by Assessing Rab10 Phosphorylation.
Ying Fan, Francesca Tonelli, Shalini Padmanabhan, Marco A S Baptista, Lindsey Riley, Andrew Howden

J Vis Exp· March 2020

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Quantitative analysis of how Myc controls T cell proteomes and metabolic pathways during T cell activation.
Julia M Marchingo, Linda V Sinclair, Andrew Jm Howden, Doreen A Cantrell

Elife· February 2020

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Quantitative analysis of T cell proteomes and environmental sensors during T cell differentiation.
Andrew J M Howden, Jens L Hukelmann, Alejandro Brenes, Laura Spinelli, Linda V Sinclair

Nat Immunol· November 2019

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