Publications by authors named "Andrew J Pope"

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Discovery and Development of TMPRSS6 Inhibitors Modulating Hepcidin Levels in Human Hepatocytes.
François Béliveau, Aarti Tarkar, Sébastien P Dion, Antoine Désilets, Mariana Gabriela Ghinet, Andrew J Pope

Cell Chem Biol· November 2019

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Identification via a Parallel Hit Progression Strategy of Improved Small Molecule Inhibitors of the Malaria Purine Uptake Transporter that Inhibit Parasite Proliferation.
Yvett Sosa, Roman Deniskin, I J Frame, Matthew S Steiginga, Deepak Bandyopadhyay, Andrew J Pope

ACS Infect Dis· October 2019

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Author Correction: Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening.
Carl A Machutta, Christopher S Kollmann, Kenneth E Lind, Xiaopeng Bai, Pan F Chan, Andrew J Pope

Nat Commun· July 2018

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Inhibitors of LexA Autoproteolysis and the Bacterial SOS Response Discovered by an Academic-Industry Partnership.
Charlie Y Mo, Matthew J Culyba, Trevor Selwood, Jeffrey M Kubiak, Zachary M Hostetler, Andrew J Pope

ACS Infect Dis· March 2018

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Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening.
Carl A Machutta, Christopher S Kollmann, Kenneth E Lind, Xiaopeng Bai, Pan F Chan, Andrew J Pope

Nat Commun· July 2017

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A High-Content Imaging Screen for Cellular Regulators of β-Catenin Protein Abundance.
Xin Zeng, Monica Montoute, Tiger W Bee, Hong Lin, Lorena A Kallal, Andrew J Pope

J Biomol Screen· March 2016

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Cell-Based Selection Expands the Utility of DNA-Encoded Small-Molecule Library Technology to Cell Surface Drug Targets: Identification of Novel Antagonists of the NK3 Tachykinin Receptor.
Zining Wu, Todd L Graybill, Xin Zeng, Michael Platchek, Jean Zhang, Andrew J Pope

ACS Comb Sci· December 2015

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A novel approach applying a chemical biology strategy in phenotypic screening reveals pathway-selective regulators of histone 3 K27 tri-methylation.
Yan Liu, Michael Platchek, Burcu Kement, Weilin T Bee, Maggie Truong, Andrew J Pope

Mol Biosyst· February 2014

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Development of phenotypic screening assays for γ-globin induction using primary human bone marrow day 7 erythroid progenitor cells.
Hu Li, Wensheng Xie, Elizabeth R Gore, Monica N Montoute, Weilin Tiger Bee, Andrew J Pope

J Biomol Screen· December 2013

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Development and validation of reagents and assays for EZH2 peptide and nucleosome high-throughput screens.
Elsie Diaz, Carl A Machutta, Stephanie Chen, Yong Jiang, Christopher Nixon, Andrew J Pope

J Biomol Screen· December 2012

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Perspectives on the discovery of small-molecule modulators for epigenetic processes.
Quinn Lu, Amy M Quinn, Mehul P Patel, Simon F Semus, Alan P Graves, Andrew J Pope

J Biomol Screen· June 2012

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Conformational restriction of methionyl tRNA synthetase inhibitors leading to analogues with potent inhibition and excellent gram-positive antibacterial activity.
Richard L Jarvest, John M Berge, Pamela Brown, Catherine S V Houge-Frydrych, Peter J O'Hanlon, Andrew J Pope

Bioorg Med Chem Lett· April 2003

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Single-molecule detection technologies in miniaturized high-throughput screening: fluorescence intensity distribution analysis.
Ulrich Haupts, Martin Rüdiger, Stephen Ashman, Sandra Turconi, Ryan Bingham, Andrew J Pope

J Biomol Screen· February 2003

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A standard operating procedure for assessing liquid handler performance in high-throughput screening.
Paul B Taylor, Stephen Ashman, Stuart M Baddeley, Stacy L Bartram, Clive D Battle, Andrew J Pope

J Biomol Screen· December 2002

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The antimicrobial natural product chuangxinmycin and some synthetic analogues are potent and selective inhibitors of bacterial tryptophanyl tRNA synthetase.
Murray J Brown, Paul S Carter, Ashley S Fenwick, Andrew P Fosberry, Dieter W Hamprecht, Andrew J Pope

Bioorg Med Chem Lett· November 2002

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Nanomolar inhibitors of Staphylococcus aureus methionyl tRNA synthetase with potent antibacterial activity against gram-positive pathogens.
Richard L Jarvest, John M Berge, Valerie Berry, Helen F Boyd, Murray J Brown, Andrew J Pope

J Med Chem· May 2002

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