Publications by authors named "Andrew Niles"

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Bioluminescence-based assays for quantifying endogenous protein interactions in live cells.
Andrew L Niles, Michael R C Dibble, Thomas Machleidt, Kelli Martino, Matthew R Swiatnicki

J Biol Chem· August 2025

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A Nondestructive, Real-Time Annexin V Apoptosis Assay.
Andrew L Niles, Kevin R Kupcho

Methods Mol Biol· September 2022

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Treating Cells as Reagents to Design Reproducible Assays.
Terry L Riss, Richard A Moravec, Sarah J Duellman, Andrew L Niles

SLAS Discov· December 2021

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A live-cell assay for the real-time assessment of extracellular ATP levels.
Andrew L Niles, James J Cali, Dan F Lazar

Anal Biochem· September 2021

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A Real-Time, Bioluminescent Apoptosis Assay.
Kevin R Kupcho, Andrew L Niles

Methods Mol Biol· June 2021

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A real-time, bioluminescent annexin V assay for the assessment of apoptosis.
Kevin Kupcho, John Shultz, Robin Hurst, Jim Hartnett, Wenhui Zhou, Andrew Niles

Apoptosis· February 2019

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Target engagement and drug residence time can be observed in living cells with BRET.
Matthew B Robers, Melanie L Dart, Carolyn C Woodroofe, Chad A Zimprich, Thomas A Kirkland, Andrew L Niles

Nat Commun· December 2015

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"Multiplexed viability, cytotoxicity, and caspase activity assays".
Andrew L Niles, Terry L Riss

Methods Mol Biol· June 2015

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Discovering protein interactions and characterizing protein function using HaloTag technology.
Danette L Daniels, Jacqui Méndez, Hélène Benink, Andrew Niles, Nancy Murphy

J Vis Exp· July 2014

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Validation of a HTS-amenable assay to detect drug-induced mitochondrial toxicity in the absence and presence of cell death.
Rachel Swiss, Andrew Niles, James J Cali, Sashi Nadanaciva, Yvonne Will

Toxicol In Vitro· September 2013

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A bioluminogenic HDAC activity assay: validation and screening.
Francoise Halley, Jeanette Reinshagen, Bernhard Ellinger, Markus Wolf, Andrew L Niles

J Biomol Screen· December 2011

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Cytotoxicity testing: measuring viable cells, dead cells, and detecting mechanism of cell death.
Terry L Riss, Richard A Moravec, Andrew L Niles

Methods Mol Biol· July 2011

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In vitro viability and cytotoxicity testing and same-well multi-parametric combinations for high throughput screening.
Andrew L Niles, Richard A Moravec, Terry L Riss

Curr Chem Genomics· June 2009

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A bioluminescent cytotoxicity assay for assessment of membrane integrity using a proteolytic biomarker.
Ming-Hsuang Cho, Andrew Niles, Ruili Huang, James Inglese, Christopher P Austin

Toxicol In Vitro· June 2008

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Update on in vitro cytotoxicity assays for drug development.
Andrew L Niles, Richard A Moravec, Terry L Riss

Expert Opin Drug Discov· June 2008

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Caspase activity assays.
Andrew L Niles, Richard A Moravec, Terry L Riss

Methods Mol Biol· February 2008

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Multiplex caspase activity and cytotoxicity assays.
Andrew L Niles, Richard A Moravec, Terry L Riss

Methods Mol Biol· February 2008

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Bioluminescent assays for ADMET.
James J Cali, Andrew Niles, Michael P Valley, Martha A O'Brien, Terry L Riss

Expert Opin Drug Metab Toxicol· January 2008

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A homogeneous assay to measure live and dead cells in the same sample by detecting different protease markers.
Andrew L Niles, Richard A Moravec, P Eric Hesselberth, Michael A Scurria, William J Daily

Anal Biochem· July 2007

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Single Step Fluorescent Caspase 3 Activity Assay: Quantifying the Inhibition of Cell Permeable Compounds in a Cell-Based System.
Jean Humpal-Winter, Andrew Niles, Martha OBrien, Bob Bulleit

ScientificWorldJournal· November 2001

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