Publications by authors named "Martha OBrien"

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Investigation of DNA Damage Response Genes Validates the Role of DNA Repair in Pediatric Cancer Risk and Identifies as a Novel Osteosarcoma Predisposition Gene.
Ninad Oak, Wenan Chen, Alise Blake, Lynn Harrison, Martha O'Brien

J Clin Oncol· December 2025

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Identification of novel inflammasome inhibitors via cellular NLRP3 target engagement assays.
Francisco Castillo, Thomas A Mackenzie, Elisabeth Domingo, Inmaculada Iañez, Matthew B Robers

SLAS Discov· September 2025

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Comprehensive investigation of DNA damage repair genes in children with cancer identifies as novel osteosarcoma predisposition gene.
Ninad Oak, Wenan Chen, Alise Blake, Lynn Harrison, Martha O'Brien

medRxiv· June 2025

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Interrogating direct NLRP3 engagement and functional inflammasome inhibition using cellular assays.
Kelly A Teske, Cesear Corona, Jennifer Wilkinson, Daniel Mamott, David A Good

Cell Chem Biol· February 2024

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Lumit: A Homogeneous Bioluminescent Immunoassay for Detecting Diverse Analytes and Intracellular Protein Targets.
Byounghoon Brian Hwang, Juliano Alves, Dan Lazar, Nidhi Nath, Laurie Engel

Methods Mol Biol· February 2023

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A bioluminescent caspase-1 activity assay rapidly monitors inflammasome activation in cells.
Martha O'Brien, Danielle Moehring, Raúl Muñoz-Planillo, Gabriel Núñez, Justin Callaway

J Immunol Methods· August 2017

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Homogeneous, bioluminescent proteasome assays.
Martha A O'Brien, Richard A Moravec, Terry L Riss, Robert F Bulleit

Methods Mol Biol· June 2015

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Self-immolative bioluminogenic quinone luciferins for NAD(P)H assays and reducing capacity-based cell viability assays.
Wenhui Zhou, Donna Leippe, Sarah Duellman, Mary Sobol, Jolanta Vidugiriene

Chembiochem· March 2014

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A bioluminescent assay for the sensitive detection of proteases.
Donna M Leippe, Duy Nguyen, Min Zhou, Troy Good, Thomas A Kirkland

Biotechniques· August 2011

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Cell-based bioluminescent assays for all three proteasome activities in a homogeneous format.
Richard A Moravec, Martha A O'Brien, William J Daily, Michael A Scurria, Laurent Bernad

Anal Biochem· April 2009

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Homogeneous, bioluminescent proteasome assays.
Martha A O'Brien, Richard A Moravec, Terry L Riss, Robert F Bulleit

Methods Mol Biol· February 2008

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Bioluminescent assays for ADMET.
James J Cali, Andrew Niles, Michael P Valley, Martha A O'Brien, Terry L Riss

Expert Opin Drug Metab Toxicol· January 2008

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Homogeneous, bioluminescent protease assays: caspase-3 as a model.
Martha A O'Brien, William J Daily, P Eric Hesselberth, Richard A Moravec, Michael A Scurria

J Biomol Screen· March 2005

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Single Step Fluorescent Caspase 3 Activity Assay: Quantifying the Inhibition of Cell Permeable Compounds in a Cell-Based System.
Jean Humpal-Winter, Andrew Niles, Martha OBrien, Bob Bulleit

ScientificWorldJournal· November 2001

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