Publications by authors named "Andrew Ratcliffe"

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Targeted temperature management in patients with intracerebral haemorrhage, subarachnoid haemorrhage, or acute ischaemic stroke: updated consensus guideline recommendations by the Neuroprotective Therapy Consensus Review (NTCR) group.
Andrea Lavinio, John Andrzejowski, Ileana Antonopoulou, Jonathan Coles, Pierce Geoghegan, Andrew Ratcliffe

Br J Anaesth· August 2023

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Discovery and structure-activity relationships of a novel oxazolidinone class of bacterial type II topoisomerase inhibitors.
Amanda Lyons, James Kirkham, Kevin Blades, David Orr, Elizabeth Dauncey, Andrew J Ratcliffe

Bioorg Med Chem Lett· June 2022

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Impact of Mitochondrial Targeting Antibiotics on Mitochondrial Function and Proliferation of Cancer Cells.
Edward J Cochrane, James Hulit, Franz P Lagasse, Tanguy Lechertier, Brett Stevenson, Andrew J Ratcliffe

ACS Med Chem Lett· April 2021

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Design, synthesis and antibacterial properties of pyrimido[4,5-b]indol-8-amine inhibitors of DNA gyrase.
David H McGarry, Ian R Cooper, Rolf Walker, Catherine E Warrilow, Mark Pichowicz, Andrew J Ratcliffe

Bioorg Med Chem Lett· September 2018

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Successful management of 70% acetic acid ingestion on the intensive care unit: A case report.
Andrew Ratcliffe, Andrew Baker, Daniel Smith

J Intensive Care Soc· February 2018

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Novel Bacterial Topoisomerase Inhibitors with Potent Broad-Spectrum Activity against Drug-Resistant Bacteria.
Cédric Charrier, Anne-Marie Salisbury, Victoria J Savage, Thomas Duffy, Emmanuel Moyo, Andrew J Ratcliffe

Antimicrob Agents Chemother· May 2017

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In vitro biological evaluation of novel broad-spectrum isothiazolone inhibitors of bacterial type II topoisomerases.
Cédric Charrier, Anne-Marie Salisbury, Victoria J Savage, Emmanuel Moyo, Henry Forward, Andrew J Ratcliffe

J Antimicrob Chemother· October 2016

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Efficacy of a Novel Tricyclic Topoisomerase Inhibitor in a Murine Model of Neisseria gonorrhoeae Infection.
Victoria J Savage, Cédric Charrier, Anne-Marie Salisbury, Helen Box, Nathan Chaffer-Malam, Andrew J Ratcliffe

Antimicrob Agents Chemother· September 2016

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Discovery and structure-activity relationships of a novel isothiazolone class of bacterial type II topoisomerase inhibitors.
Ian R Cooper, Andrew J McCarroll, David McGarry, James Kirkham, Mark Pichowicz, Andrew J Ratcliffe

Bioorg Med Chem Lett· September 2016

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Biological profiling of novel tricyclic inhibitors of bacterial DNA gyrase and topoisomerase IV.
Victoria J Savage, Cédric Charrier, Anne-Marie Salisbury, Emmanuel Moyo, Henry Forward, Andrew J Ratcliffe

J Antimicrob Chemother· July 2016

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Comparison of mortality prediction models in burns ICU patients in Pinderfields Hospital over 3 years.
Helen E Douglas, Andrew Ratcliffe, Rajdeep Sandhu, Umair Anwar

Burns· February 2015

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Intravenous macrolide use: a reminder of the dangers of rapid infusion rates.
Andrew T Ratcliffe, Khaled M Ismail

J Clin Anesth· November 2012

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Medicinal chemistry strategies to minimize phospholipidosis.
Andrew J Ratcliffe

Curr Med Chem· February 2010

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Imidazopyridines as VLA-4 integrin antagonists.
David J Phillips, Richard J Davenport, Thierry A Demaude, Fiona P Galleway, Mark W Jones, Andrew J Ratcliffe

Bioorg Med Chem Lett· July 2008

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Emerging therapies for respiratory diseases.
Ruth Lock, Steve Collingwood, Andrew Ratcliffe

Drug News Perspect· November 2007

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Synthesis and SAR of aminopyrimidines as novel c-Jun N-terminal kinase (JNK) inhibitors.
Mahbub Alam, Rebekah E Beevers, Tom Ceska, Richard J Davenport, Karen M Dickson, Andrew J Ratcliffe

Bioorg Med Chem Lett· June 2007

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Inosine 5'-monophosphate dehydrogenase inhibitors for the treatment of autoimmune diseases.
Andrew J Ratcliffe

Curr Opin Drug Discov Devel· September 2006

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Low molecular weight indole fragments as IMPDH inhibitors.
Rebekah E Beevers, George M Buckley, Natasha Davies, Joanne L Fraser, Francis C Galvin, Andrew J Ratcliffe

Bioorg Med Chem Lett· May 2006

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Novel indole inhibitors of IMPDH from fragments: synthesis and initial structure-activity relationships.
Rebekah E Beevers, George M Buckley, Natasha Davies, Joanne L Fraser, Francis C Galvin, Andrew J Ratcliffe

Bioorg Med Chem Lett· May 2006

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Novel 7-methoxy-6-oxazol-5-yl-2,3-dihydro-1H-quinazolin-4-ones as IMPDH inhibitors.
Helen L Birch, George M Buckley, Natasha Davies, Hazel J Dyke, Elizabeth J Frost, Andrew J Ratcliffe

Bioorg Med Chem Lett· December 2005

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