Publications by authors named "Andrew Stott"

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Discovery of CVN293, a Brain Permeable KCNK13 (THIK-1) Inhibitor Suitable for Clinical Assessment.
Roland W Bürli, Kevin J Doyle, Louise Dickson, Anna Rowland, Kim Matthews, Andrew J Stott

ACS Med Chem Lett· May 2024

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Identification and Optimization of RNA-Splicing Modulators as Huntingtin Protein-Lowering Agents for the Treatment of Huntington's Disease.
Longbin Liu, Karine Malagu, Alan F Haughan, Vinod Khetarpal, Andrew J Stott

J Med Chem· September 2023

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The differential ability of two species of seagrass to use carbon dioxide and bicarbonate and their modelled response to rising concentrations of inorganic carbon.
Stephen Christopher Maberly, Andrew W Stott, Brigitte Gontero

Front Plant Sci· September 2022

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Planktonic foraminifera organic carbon isotopes as archives of upper ocean carbon cycling.
Babette A A Hoogakker, Caroline Anderson, Tommaso Paoloni, Andrew Stott, Helen Grant

Nat Commun· August 2022

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Identification of a Potent, Selective, and Brain-Penetrant Rho Kinase Inhibitor and its Activity in a Mouse Model of Huntington's Disease.
Tammy Ladduwahetty, Matthew R Lee, Michel C Maillard, Roger Cachope, Daniel Todd, Andrew J Stott

J Med Chem· July 2022

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The importance of plasma protein and tissue binding in a drug discovery program to successfully deliver a preclinical candidate.
Elizabeth Hann, Karine Malagu, Andrew Stott, Huw Vater

Prog Med Chem· June 2022

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Evaluation of 5-(Trifluoromethyl)-1,2,4-oxadiazole-Based Class IIa HDAC Inhibitors for Huntington's Disease.
Andrew J Stott, Michel C Maillard, Vahri Beaumont, David Allcock, Omar Aziz

ACS Med Chem Lett· March 2021

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Development and characterization of a CNS-penetrant benzhydryl hydroxamic acid class IIa histone deacetylase inhibitor.
Christopher A Luckhurst, Omar Aziz, Vahri Beaumont, Roland W Bürli, Perla Breccia, Andrew J Stott

Bioorg Med Chem Lett· January 2019

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How does elevated ozone reduce methane emissions from peatlands?
Sylvia Toet, Viktoria Oliver, Phil Ineson, Sophie McLoughlin, Thorunn Helgason, Andrew W Stott

Sci Total Environ· February 2017

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Potent, Selective, and CNS-Penetrant Tetrasubstituted Cyclopropane Class IIa Histone Deacetylase (HDAC) Inhibitors.
Christopher A Luckhurst, Perla Breccia, Andrew J Stott, Omar Aziz, Helen L Birch

ACS Med Chem Lett· January 2016

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Seasonal variation in denitrification and dissimilatory nitrate reduction to ammonia process rates and corresponding key functional genes along an estuarine nitrate gradient.
Cindy J Smith, Liang F Dong, John Wilson, Andrew Stott, A Mark Osborn

Front Microbiol· June 2015

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Inter- and intramolecular annulation strategies to a cyclopentanone building block containing an all-carbon quaternary stereogenic center.
Stephen D Penrose, Andrew J Stott, Perla Breccia, Alan F Haughan, Roland W Bürli

Org Lett· March 2015

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Microbial carbon mineralization in tropical lowland and montane forest soils of Peru.
Jeanette Whitaker, Nicholas Ostle, Niall P McNamara, Andrew T Nottingham, Andrew W Stott

Front Microbiol· January 2015

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Design, synthesis, and biological evaluation of potent and selective class IIa histone deacetylase (HDAC) inhibitors as a potential therapy for Huntington's disease.
Roland W Bürli, Christopher A Luckhurst, Omar Aziz, Kim L Matthews, Dawn Yates, Andrew J Stott

J Med Chem· December 2013

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Root and arbuscular mycorrhizal mycelial interactions with soil microorganisms in lowland tropical forest.
Andrew T Nottingham, Benjamin L Turner, Klaus Winter, Paul M Chamberlain, Andrew Stott

FEMS Microbiol Ecol· July 2013

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Changes in benthic denitrification, nitrate ammonification, and anammox process rates and nitrate and nitrite reductase gene abundances along an estuarine nutrient gradient (the Colne estuary, United Kingdom).
Liang F Dong, Cindy J Smith, Sokratis Papaspyrou, Andrew Stott, A Mark Osborn

Appl Environ Microbiol· May 2009

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Soil invertebrates disrupt carbon flow through fungal networks.
David Johnson, Martin Krsek, Elizabeth M H Wellington, Andrew W Stott, Lisa Cole

Science· August 2005

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Direct dating of archaeological pottery by compound-specific 14C analysis of preserved lipids.
Andrew W Stott, Robert Berstan, Richard P Evershed, Christopher Bronk-Ramsey, Robert E M Hedges

Anal Chem· October 2003

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Development of a trace gas stable isotope capture system in a mobile laboratory for temporal and spatial sampling of field and laboratory experiments.
Niall McNamara, David Benham, Darren Sleep, Helen Grant, Andrew Stott

Rapid Commun Mass Spectrom· January 2003

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Chemistry of archaeological animal fats.
Richard P Evershed, Stephanie N Dudd, Mark S Copley, Robert Berstan, Andrew W Stott

Acc Chem Res· August 2002

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