Publications by authors named "Andrew Wells"

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3D chromatin-based variant-to-gene maps across 57 human cell types reveal the cellular and genetic architecture of autoimmune disease susceptibility.
Khanh B Trang, Prabhat Sharma, Laura Cook, Zachary Mount, Rajan M Thomas, Andrew D Wells

Genome Biol· December 2025

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GWAS-informed data integration and non-coding CRISPRi screen illuminate genetic etiology of bone mineral density.
Mitchell Conery, James A Pippin, Yadav Wagley, Khanh Trang, Matthew C Pahl, Andrew D Wells

Genome Biol· October 2025

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Large-scale multiomic analysis identifies non-coding somatic driver mutations and nominates as a driver gene for pancreatic ductal adenocarcinoma.
Jun Zhong, Aidan O'Brien, Minal B Patel, Daina Eiser, Michael Mobaraki, Andrew D Wells

Gut· October 2025

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Human KIT Antibody Briquilimab Diminishes Anaphylactic Responses in Mice Expressing Chimeric Human-Mouse KIT.
Hye-Sook Kwon, Song Eun Lee, Ajay Sharma, Minyoung Youn, Charles A Chang, Andrew Wells

Allergy· October 2025

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Mapping chromatin interactions at melanoma susceptibility loci uncovers distant cis-regulatory gene targets.
Rohit Thakur, Mai Xu, Hayley Sowards, Joshuah Yon, Lea Jessop, Andrew D Wells

Am J Hum Genet· July 2025

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Shared and unique 3D genomic features of substance use disorders across multiple cell types.
Khanh B Trang, Alessandra Chesi, Sylvanus Toikumo, James A Pippin, Matthew C Pahl, Andrew D Wells

medRxiv· June 2025

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Correction: The effect of prolonged interval and continuous exercise in the heat on circulatory markers of intestinal barrier integrity.
Zachary McKenna, Jonathan Houck, Jeremy Ducharme, Zidong Li, Quint Berkemeier, Andrew Wells

Eur J Appl Physiol· June 2025

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Open-science discovery of DNDI-6510, a compound that addresses genotoxic and metabolic liabilities of the COVID Moonshot SARS-CoV-2 Mpro lead inhibitor.
Ed J Griffen, Daren Fearon, Briana L McGovern, Lizbe Koekemoer, Blake H Balcomb, Andrew Wells

bioRxiv· June 2025

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3D chromatin-based variant-to-gene maps across 57 human cell types reveal the cellular and genetic architecture of autoimmune disease susceptibility.
Khanh B Trang, Prabhat Sharma, Laura Cook, Zachary Mount, Rajan M Thomas, Andrew D Wells

medRxiv· May 2025

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Stepwise Approach to Robotic Anterior Resection.
Rasa Sadoughi, Andrew R Wells, Najaf Siddiqi

Dis Colon Rectum· May 2025

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Age-related breakdown in networks of inter-muscular coordination.
Sergi Garcia-Retortillo, Óscar Abenza, Fidanka Vasileva, Natàlia Balagué, Robert Hristovski, Andrew Wells

Geroscience· April 2025

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Trans-ancestry genome-wide association meta-analysis of gallstone disease.
Junghyun Lim, Marijana Vujkovic, Michael G Levin, Kim Lorenz, Benjamin F Voight, Andrew D Wells

medRxiv· March 2025

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Laparoscopic subtotal colectomy with end ileostomy-A video vignette.
Maaz Yusufi, Rasa Sadoughi, Andrew Wells, Najaf Siddiqi

Colorectal Dis· January 2025

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3D genomic features across >50 diverse cell types reveal insights into the genomic architecture of childhood obesity.
Khanh B Trang, Matthew C Pahl, James A Pippin, Chun Su, Sheridan H Littleton, Andrew D Wells

Elife· January 2025

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The impact of physical training on the Fontan circulation population: A systematic review and meta-analysis of randomized controlled trials.
Eric Shih Katsuyama, Christian Ken Fukunaga, Wilson Falco, Sofia Helena Vitte, Andrew Wells

Eur J Prev Cardiol· January 2025

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Implicating type 2 diabetes effector genes in relevant metabolic cellular models using promoter-focused Capture-C.
Nicholas A Wachowski, James A Pippin, Keith Boehm, Sumei Lu, Michelle E Leonard, Andrew D Wells

Diabetologia· December 2024

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Angiotensin receptor blockers modulate the lupus CD4+ T cell epigenome characterized by TNF family-linked signaling.
Andrew P Hart, Jonathan J Kotzin, Steffan W Schulz, Jonathan S Dunham, Alison L Keenan, Andrew D Wells

JCI Insight· December 2024

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Mapping chromatin interactions at melanoma susceptibility loci and cell-type specific dataset integration uncovers distant gene targets of -regulation.
Rohit Thakur, Mai Xu, Hayley Sowards, Joshuah Yon, Lea Jessop, Andrew D Wells

medRxiv· November 2024

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The common variable immunodeficiency IgM repertoire narrowly recognizes erythrocyte and platelet glycans.
Carole Le Coz, Melissa Trofa, Dorothy L Butler, Samuel Yoon, Tian Tian, Andrew D Wells

J Allergy Clin Immunol· September 2024

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Dynamic chromatin architecture identifies new autoimmune-associated enhancers for and novel genes regulating CD4+ T cell activation.
Matthew C Pahl, Prabhat Sharma, Rajan M Thomas, Zachary Thompson, Zachary Mount, Andrew D Wells

Elife· September 2024

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Large-scale multi-omic analysis identifies noncoding somatic driver mutations and nominates as a driver gene for pancreatic ductal adenocarcinoma.
Jun Zhong, Aidan O'Brien, Minal Patel, Daina Eiser, Michael Mobaraki, Andrew D Wells

medRxiv· September 2024

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Variant-to-function mapping of late-onset Alzheimer's disease GWAS signals in human microglial cell models implicates at the locus.
Elizabeth A Burton, Mariana Argenziano, Kieona Cook, Molly Ridler, Sumei Lu, Andrew D Wells

bioRxiv· August 2024

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Osteoporosis GWAS-implicated locus contextually regulates osteoblastic and chondrogenic fate of mesenchymal stem/progenitor cells through oscillating miR-199a-5p levels.
Gurcharan Kaur, James A Pippin, Solomon Chang, Justin Redmond, Alessandra Chesi, Andrew D Wells

JBMR Plus· May 2024

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Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3' UTR of FAIM2.
Sheridan H Littleton, Khanh B Trang, Christina M Volpe, Kieona Cook, Nicole DeBruyne, Andrew D Wells

Cell Genom· May 2024

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Foxp3 depends on Ikaros for control of regulatory T cell gene expression and function.
Rajan M Thomas, Matthew C Pahl, Liqing Wang, Struan F A Grant, Wayne W Hancock, Andrew D Wells

Elife· April 2024

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