Publications by authors named "Andy Zeng"

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Response to Immune Checkpoint Blockade is Enhanced in the Presence of Hematopoietic TET2 Inactivation.
Vincent Rondeau, Suraj Bansal, Marco M Buttigieg, Andy G X Zeng, Darryl Y Chan

Cancer Res· November 2025

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Glutaredoxin 2 is essential for AML survival through mitochondrial permeability transition pore regulation.
Tianyi Ling, Cristiana O'Brien, Jonathan St-Germain, Vincent Rondeau, Mary Shi, Andy G X Zeng

Blood· November 2025

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Single-cell Transcriptional Atlas of Human Hematopoiesis Reveals Genetic and Hierarchy-Based Determinants of Aberrant AML Differentiation.
Andy G X Zeng, Ilaria Iacobucci, Sayyam Shah, Amanda Mitchell, Gordon Wong

Blood Cancer Discov· July 2025

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Multipotent lineage potential in B cell acute lymphoblastic leukemia is associated with distinct cellular origins and clinical features.
Ilaria Iacobucci, Andy G X Zeng, Qingsong Gao, Laura Garcia-Prat, Pradyumna Baviskar

Nat Cancer· July 2025

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Overcoming CD226-related immune evasion in acute myeloid leukemia with CD38 CAR-engineered NK cells.
Luciana Melo Garcia, Achintyan Gangadharan, Pinaki Banerjee, Ye Li, Andy G X Zeng

Cell Rep· January 2025

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Single-cell transcriptional mapping reveals genetic and non-genetic determinants of aberrant differentiation in AML.
Andy G X Zeng, Ilaria Iacobucci, Sayyam Shah, Amanda Mitchell, Gordon Wong

bioRxiv· November 2024

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Selective advantage of mutant stem cells in human clonal hematopoiesis is associated with attenuated response to inflammation and aging.
Niels Asger Jakobsen, Sven Turkalj, Andy G X Zeng, Bilyana Stoilova, Marlen Metzner

Cell Stem Cell· August 2024

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Training Outcomes and Satisfaction in Canadian MD/PhD and MD/MSc Programs: Findings from a National Survey.
Mimosa Luigi, Charles Yin, Ehsan Misaghi, Robert X Lao, Bryce J M Bogie, Andy Zeng

Clin Invest Med· June 2024

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Editorial: Language, affordance and physics in robot cognition and intelligent systems.
Nutan Chen, Walterio W Mayol-Cuevas, Maximilian Karl, Elie Aljalbout, Andy Zeng

Front Robot AI· January 2024

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SINGLE CELL DISSECTION OF DEVELOPMENTAL ORIGINS AND TRANSCRIPTIONAL HETEROGENEITY IN B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA.
Ilaria Iacobucci, Andy G X Zeng, Qingsong Gao, Laura Garcia-Prat, Pradyumna Baviskar

bioRxiv· December 2023

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Simultaneous inhibition of Sirtuin 3 and cholesterol homeostasis targets acute myeloid leukemia stem cells by perturbing fatty acid β-oxidation and inducing lipotoxicity.
Cristiana O'Brien, Tianyi Ling, Jacob M Berman, Rachel Culp-Hill, Julie A Reisz, Andy Zeng

Haematologica· September 2023

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Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia.
Winnie L Kan, Urmi Dhagat, Kerstin B Kaufmann, Timothy R Hercus, Tracy L Nero, Andy G X Zeng

Cancer Discov· August 2023

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Transcriptomic classes of BCR-ABL1 lymphoblastic leukemia.
Jaeseung C Kim, Michelle Chan-Seng-Yue, Sabrina Ge, Andy G X Zeng, Karen Ng

Nat Genet· July 2023

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Single-cell chromatin accessibility profiling of acute myeloid leukemia reveals heterogeneous lineage composition upon therapy-resistance.
Huihui Fan, Feng Wang, Andy Zeng, Alex Murison, Katarzyna Tomczak

Commun Biol· July 2023

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KDM6 demethylases integrate DNA repair gene regulation and loss of KDM6A sensitizes human acute myeloid leukemia to PARP and BCL2 inhibition.
Liberalis Debraj Boila, Subhadeep Ghosh, Subham K Bandyopadhyay, Liqing Jin, Alex Murison, Andy G X Zeng

Leukemia· April 2023

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Identification and characterization of in vitro expanded hematopoietic stem cells.
James L C Che, Daniel Bode, Iwo Kucinski, Alyssa H Cull, Fiona Bain, Andy G X Zeng

EMBO Rep· October 2022

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A cellular hierarchy framework for understanding heterogeneity and predicting drug response in acute myeloid leukemia.
Andy G X Zeng, Suraj Bansal, Liqing Jin, Amanda Mitchell, Weihsu Claire Chen

Nat Med· June 2022

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Identification of the global miR-130a targetome reveals a role for TBL1XR1 in hematopoietic stem cell self-renewal and t(8;21) AML.
Gabriela Krivdova, Veronique Voisin, Erwin M Schoof, Sajid A Marhon, Alex Murison, Andy G X Zeng

Cell Rep· March 2022

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Enhancer Hijacking Drives Oncogenic Expression in Lineage-Ambiguous Stem Cell Leukemia.
Lindsey E Montefiori, Sonja Bendig, Zhaohui Gu, Xiaolong Chen, Petri Pölönen, Andy Zeng

Cancer Discov· November 2021

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TFEB-mediated endolysosomal activity controls human hematopoietic stem cell fate.
Laura García-Prat, Kerstin B Kaufmann, Florin Schneiter, Veronique Voisin, Alex Murison, Andy G X Zeng

Cell Stem Cell· October 2021

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A latent subset of human hematopoietic stem cells resists regenerative stress to preserve stemness.
Kerstin B Kaufmann, Andy G X Zeng, Etienne Coyaud, Laura Garcia-Prat, Efthymia Papalexi

Nat Immunol· June 2021

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Sphingosine-1-phosphate receptor 3 potentiates inflammatory programs in normal and leukemia stem cells to promote differentiation.
Stephanie Z Xie, Kerstin B Kaufmann, Weijia Wang, Michelle Chan-Seng-Yue, Olga I Gan, Andy G X Zeng

Blood Cancer Discov· January 2021

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Integration of intra-sample contextual error modeling for improved detection of somatic mutations from deep sequencing.
Sagi Abelson, Andy G X Zeng, Ido Nofech-Mozes, Ting Ting Wang, Stanley W K Ng

Sci Adv· December 2020

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Newsletter Fall 2020: Clinician Investigator Trainee Association of Canada (CITAC).
Valera Castanov, Andy Zeng, Bahar Behrouzi, Jillian Macklin, Sophie Hu

Clin Invest Med· September 2020

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Fundamental trends within falling match rates: Insights from the past decade of Canadian residency matching data.
Andy G X Zeng, Connor T A Brenna, Silvio Ndoja

Can Med Educ J· July 2020

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