Publications by authors named "Angelo Ranise"

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Further SAR studies on bicyclic basic merbarone analogues as potent antiproliferative agents.
Andrea Spallarossa, Chiara Rotolo, Claudia Sissi, Giuseppe Marson, Maria Laura Greco, Angelo Ranise

Bioorg Med Chem· November 2013

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Homology modeling in tandem with 3D-QSAR analyses: a computational approach to depict the agonist binding site of the human CB2 receptor.
Elena Cichero, Alessia Ligresti, Marco Allarà, Vincenzo di Marzo, Zelda Lazzati, Angelo Ranise

Eur J Med Chem· September 2011

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Parallel synthesis of O-phenoxyethyl and O-adamantyl N-acyl thiocarbamates endowed with antiproliferative activity.
Andrea Spallarossa, Sara Cesarini, Silvia Schenone, Angelo Ranise

Arch Pharm (Weinheim)· June 2009

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Parallel synthesis, molecular modelling and further structure-activity relationship studies of new acylthiocarbamates as potent non-nucleoside HIV-1 reverse transcriptase inhibitors.
Andrea Spallarossa, Sara Cesarini, Angelo Ranise, Silvia Schenone, Olga Bruno

Eur J Med Chem· May 2009

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6-amino-4-oxo-1,3-diphenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carbonyl derivatives as a new class of potent inhibitors of Interleukin-8-induced neutrophil chemotaxis.
Sara Cesarini, Andrea Spallarossa, Angelo Ranise, Olga Bruno, Nicoletta Arduino

Bioorg Med Chem· May 2009

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Novel modifications in the series of O-(2-phthalimidoethyl)-N-substituted thiocarbamates and their ring-opened congeners as non-nucleoside HIV-1 reverse transcriptase inhibitors.
Andrea Spallarossa, Sara Cesarini, Angelo Ranise, Olga Bruno, Silvia Schenone

Eur J Med Chem· April 2009

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N-acylated and N,N'-diacylated imidazolidine-2-thione derivatives and N,N'-diacylated tetrahydropyrimidine-2(1H)-thione analogues: synthesis and antiproliferative activity.
Sara Cesarini, Andrea Spallarossa, Angelo Ranise, Silvia Schenone, Camillo Rosano

Eur J Med Chem· March 2009

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Rational design, synthesis and biological evaluation of new 1,5-diarylpyrazole derivatives as CB1 receptor antagonists, structurally related to rimonabant.
Giulia Menozzi, Paola Fossa, Elena Cichero, Andrea Spallarossa, Angelo Ranise

Eur J Med Chem· December 2008

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Parallel one-pot synthesis and structure-activity relationship study of symmetric formimidoester disulfides as a novel class of potent non-nucleoside HIV-1 reverse transcriptase inhibitors.
Sara Cesarini, Andrea Spallarossa, Angelo Ranise, Silvia Schenone, Olga Bruno

Bioorg Med Chem· June 2008

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Thiocarbamates as non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 1: Parallel synthesis, molecular modelling and structure-activity relationship studies on O-[2-(hetero)arylethyl]-N-phenylthiocarbamates.
Sara Cesarini, Andrea Spallarossa, Angelo Ranise, Paola Fossa, Paolo La Colla

Bioorg Med Chem· April 2008

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Thiocarbamates as non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 2: Parallel synthesis, molecular modelling and structure-activity relationship studies on analogues of O-(2-phenylethyl)-N-phenylthiocarbamate.
Sara Cesarini, Andrea Spallarossa, Angelo Ranise, Olga Bruno, Paolo La Colla

Bioorg Med Chem· April 2008

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Crystal structures of HIV-1 reverse transcriptase complexes with thiocarbamate non-nucleoside inhibitors.
Andrea Spallarossa, Sara Cesarini, Angelo Ranise, Marco Ponassi, Torsten Unge

Biochem Biophys Res Commun· January 2008

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Identification of a novel pyrazolo[3,4-d]pyrimidine able to inhibit cell proliferation of a human osteogenic sarcoma in vitro and in a xenograft model in mice.
Fabrizio Manetti, Annalisa Santucci, Giada A Locatelli, Giovanni Maga, Adriano Spreafico, Angelo Ranise

J Med Chem· November 2007

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2-Phenyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazole derivatives: new potent inhibitors of fMLP-induced neutrophil chemotaxis.
Olga Bruno, Chiara Brullo, Francesco Bondavalli, Angelo Ranise, Silvia Schenone

Bioorg Med Chem Lett· July 2007

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Synthesis and biological evaluation of N-pyrazolyl-N'-alkyl/benzyl/phenylureas: a new class of potent inhibitors of interleukin 8-induced neutrophil chemotaxis.
Olga Bruno, Chiara Brullo, Francesco Bondavalli, Silvia Schenone, Angelo Ranise

J Med Chem· July 2007

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Affinity prediction on A1 adenosine receptor agonists: the chemometric approach.
Paola Fossa, Luisa Mosti, Francesco Bondavalli, Silvia Schenone, Angelo Ranise

Bioorg Med Chem· March 2006

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New 1,3,4-thiadiazole derivatives endowed with analgesic and anti-inflammatory activities.
Silvia Schenone, Chiara Brullo, Olga Bruno, Francesco Bondavalli, Angelo Ranise

Bioorg Med Chem· March 2006

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Pyrazolo[3,4-d]pyrimidines as potent antiproliferative and proapoptotic agents toward A431 and 8701-BC cells in culture via inhibition of c-Src phosphorylation.
Fabio Carraro, Antonella Naldini, Annalisa Pucci, Giada A Locatelli, Giovanni Maga, Angelo Ranise

J Med Chem· March 2006

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Synthesis, antiplatelet and antithrombotic activities of new 2-substituted benzopyrano[4,3-d]pyrimidin-4-cycloamines and 4-amino/cycloamino-benzopyrano[4,3-d]pyrimidin-5-ones.
Olga Bruno, Chiara Brullo, Silvia Schenone, Francesco Bondavalli, Angelo Ranise

Bioorg Med Chem· January 2006

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Synthesis and 3D QSAR of new pyrazolo[3,4-b]pyridines: potent and selective inhibitors of A1 adenosine receptors.
Fabrizio Manetti, Silvia Schenone, Francesco Bondavalli, Chiara Brullo, Olga Bruno, Angelo Ranise

J Med Chem· November 2005

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Structure-based design, parallel synthesis, structure-activity relationship, and molecular modeling studies of thiocarbamates, new potent non-nucleoside HIV-1 reverse transcriptase inhibitor isosteres of phenethylthiazolylthiourea derivatives.
Angelo Ranise, Andrea Spallarossa, Sara Cesarini, Francesco Bondavalli, Silvia Schenone

J Med Chem· June 2005

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New pyrazolo[3,4-b]pyridones as selective A(1) adenosine receptor antagonists: synthesis, biological evaluation and molecular modelling studies.
Paola Fossa, Marco Pestarino, Giulia Menozzi, Luisa Mosti, Silvia Schenone, Angelo Ranise

Org Biomol Chem· June 2005

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Antiproliferative activity of new 1-aryl-4-amino-1H-pyrazolo[3,4-d]pyrimidine derivatives toward the human epidermoid carcinoma A431 cell line.
Silvia Schenone, Olga Bruno, Francesco Bondavalli, Angelo Ranise, Luisa Mosti

Eur J Med Chem· November 2004

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Synthesis, antimicrobial activity and molecular modeling studies of halogenated 4-[1H-imidazol-1-yl(phenyl)methyl]-1,5-diphenyl-1H-pyrazoles.
Giulia Menozzi, Luisa Merello, Paola Fossa, Silvia Schenone, Angelo Ranise

Bioorg Med Chem· October 2004

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Pyrazolo[3,4-d]pyrimidines endowed with antiproliferative activity on ductal infiltrating carcinoma cells.
Fabio Carraro, Annalisa Pucci, Antonella Naldini, Silvia Schenone, Olga Bruno, Angelo Ranise

J Med Chem· March 2004

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