Publications by authors named "Torsten Unge"

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Novel pseudopeptides incorporating a benzodiazepine-based turn mimetic--targeting Mycobacterium tuberculosis ribonucleotide reductase.
Johanna Nurbo, Daniel J Ericsson, Ulrika Rosenström, Daniel Muthas, Anna M Jansson, Torsten Unge

Bioorg Med Chem· April 2013

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Structural studies on Mycobacterium tuberculosis DXR in complex with the antibiotic FR-900098.
Christofer Björkelid, Terese Bergfors, Torsten Unge, Sherry L Mowbray, T Alwyn Jones

Acta Crystallogr D Biol Crystallogr· February 2012

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Design, synthesis, and X-ray crystallographic studies of α-aryl substituted fosmidomycin analogues as inhibitors of Mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate reductoisomerase.
Mounir Andaloussi, Lena M Henriksson, Anna Więckowska, Martin Lindh, Christofer Björkelid, Torsten Unge

J Med Chem· July 2011

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Structural and functional studies of mycobacterial IspD enzymes.
Christofer Björkelid, Terese Bergfors, Lena M Henriksson, Ana Laura Stern, Torsten Unge

Acta Crystallogr D Biol Crystallogr· May 2011

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Flexibility and communication within the structure of the Mycobacterium smegmatis methionyl-tRNA synthetase.
Henrik Ingvarsson, Torsten Unge

FEBS J· October 2010

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Structure and functionality in flavivirus NS-proteins: perspectives for drug design.
Michela Bollati, Karin Alvarez, René Assenberg, Cécile Baronti, Bruno Canard, Torsten Unge

Antiviral Res· August 2010

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Antiviral strategies to control calicivirus infections.
Jacques Rohayem, Mirko Bergmann, Julia Gebhardt, Ernest Gould, Paul Tucker, Torsten Unge

Antiviral Res· August 2010

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Structural analysis of mycobacterial branched-chain aminotransferase: implications for inhibitor design.
Alina Castell, Christian Mille, Torsten Unge

Acta Crystallogr D Biol Crystallogr· May 2010

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Identification of small peptides mimicking the R2 C-terminus of Mycobacterium tuberculosis ribonucleotide reductase.
Daniel J Ericsson, Johanna Nurbo, Daniel Muthas, Kalle Hertzberg, Gunnar Lindeberg, Torsten Unge

J Pept Sci· March 2010

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HIV-1 protease inhibitors with a transition-state mimic comprising a tertiary alcohol: improved antiviral activity in cells.
A K Mahalingam, Linda Axelsson, Jenny K Ekegren, Johan Wannberg, Jacob Kihlström, Torsten Unge

J Med Chem· January 2010

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Structure of the methyltransferase domain from the Modoc virus, a flavivirus with no known vector.
Anna M Jansson, Emma Jakobsson, Patrik Johansson, Violaine Lantez, Bruno Coutard, Torsten Unge

Acta Crystallogr D Biol Crystallogr· August 2009

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Crystallization of Mycobacterium smegmatis methionyl-tRNA synthetase in the presence of methionine and adenosine.
Henrik Ingvarsson, T Alwyn Jones, Torsten Unge

Acta Crystallogr Sect F Struct Biol Cryst Commun· June 2009

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The active form of the norovirus RNA-dependent RNA polymerase is a homodimer with cooperative activity.
Martin Högbom, Katrin Jäger, Ivonne Robel, Torsten Unge, Jacques Rohayem

J Gen Virol· February 2009

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Two-carbon-elongated HIV-1 protease inhibitors with a tertiary-alcohol-containing transition-state mimic.
Xiongyu Wu, Per Ohrngren, Jenny K Ekegren, Johan Unge, Torsten Unge

J Med Chem· February 2008

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Crystal structures of HIV-1 reverse transcriptase complexes with thiocarbamate non-nucleoside inhibitors.
Andrea Spallarossa, Sara Cesarini, Angelo Ranise, Marco Ponassi, Torsten Unge

Biochem Biophys Res Commun· January 2008

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Design, synthesis and evaluation of peptide inhibitors of Mycobacterium tuberculosis ribonucleotide reductase.
Johanna Nurbo, Annette K Roos, Daniel Muthas, Erik Wahlström, Daniel J Ericsson, Torsten Unge

J Pept Sci· December 2007

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Structures of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate reductoisomerase provide new insights into catalysis.
Lena M Henriksson, Torsten Unge, Jens Carlsson, Johan Aqvist, Sherry L Mowbray

J Biol Chem· July 2007

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Insights into the inter-ring plasticity of caseinolytic proteases from the X-ray structure of Mycobacterium tuberculosis ClpP1.
Henrik Ingvarsson, María J Maté, Martin Högbom, Denis Portnoï, Nadia Benaroudj, Torsten Unge

Acta Crystallogr D Biol Crystallogr· February 2007

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The 1.9 A resolution structure of Mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate reductoisomerase, a potential drug target.
Lena M Henriksson, Christofer Björkelid, Sherry L Mowbray, Torsten Unge

Acta Crystallogr D Biol Crystallogr· July 2006

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Biosensor-based kinetic characterization of the interaction between HIV-1 reverse transcriptase and non-nucleoside inhibitors.
Matthis Geitmann, Torsten Unge, U Helena Danielson

J Med Chem· April 2006

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Interaction kinetic characterization of HIV-1 reverse transcriptase non-nucleoside inhibitor resistance.
Matthis Geitmann, Torsten Unge, U Helena Danielson

J Med Chem· April 2006

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Microwave-accelerated synthesis of P1'-extended HIV-1 protease inhibitors encompassing a tertiary alcohol in the transition-state mimicking scaffold.
Jenny K Ekegren, Nina Ginman, Asa Johansson, Hans Wallberg, Mats Larhed, Torsten Unge

J Med Chem· March 2006

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A new class of HIV-1 protease inhibitors containing a tertiary alcohol in the transition-state mimicking scaffold.
Jenny K Ekegren, Torsten Unge, Mayada Zreik Safa, Hans Wallberg, Bertil Samuelsson

J Med Chem· December 2005

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Structure of an atypical epoxide hydrolase from Mycobacterium tuberculosis gives insights into its function.
Patrik Johansson, Torsten Unge, Annette Cronin, Michael Arand, Terese Bergfors

J Mol Biol· September 2005

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Rv0216, a conserved hypothetical protein from Mycobacterium tuberculosis that is essential for bacterial survival during infection, has a double hotdog fold.
Alina Castell, Patrik Johansson, Torsten Unge, T Alwyn Jones, Kristina Bäckbro

Protein Sci· July 2005

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