Publications by authors named "Matthis Geitmann"

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Macrocyclic Peptides Uncover a Novel Binding Mode for Reversible Inhibitors of LSD1.
Jie Yang, Vladimir O Talibov, Stefan Peintner, Claire Rhee, Vasanthanathan Poongavanam, Matthis Geitmann

ACS Omega· March 2020

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Development of (4-Cyanophenyl)glycine Derivatives as Reversible Inhibitors of Lysine Specific Demethylase 1.
Daniel P Mould, Cristina Alli, Ulf Bremberg, Sharon Cartic, Allan M Jordan, Matthis Geitmann

J Med Chem· October 2017

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Development and evaluation of 4-(pyrrolidin-3-yl)benzonitrile derivatives as inhibitors of lysine specific demethylase 1.
Daniel P Mould, Ulf Bremberg, Allan M Jordan, Matthis Geitmann, Alison E McGonagle

Bioorg Med Chem Lett· October 2017

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Development of 5-hydroxypyrazole derivatives as reversible inhibitors of lysine specific demethylase 1.
Daniel P Mould, Ulf Bremberg, Allan M Jordan, Matthis Geitmann, Alba Maiques-Diaz

Bioorg Med Chem Lett· July 2017

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Identification and Characterization of an Irreversible Inhibitor of CDK2.
Elizabeth Anscombe, Elisa Meschini, Regina Mora-Vidal, Mathew P Martin, David Staunton, Matthis Geitmann

Chem Biol· September 2015

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Structural basis of ligand recognition in 5-HT3 receptors.
Divya Kesters, Andrew J Thompson, Marijke Brams, René van Elk, Radovan Spurny, Matthis Geitmann

EMBO Rep· January 2013

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Mechanistic and kinetic characterization of hepatitis C virus NS3 protein interactions with NS4A and protease inhibitors.
Matthis Geitmann, Göran Dahl, U Helena Danielson

J Mol Recognit· July 2011

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Deconstruction of non-nucleoside reverse transcriptase inhibitors of human immunodeficiency virus type 1 for exploration of the optimization landscape of fragments.
Peter Brandt, Matthis Geitmann, U Helena Danielson

J Med Chem· February 2011

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Identification of a novel scaffold for allosteric inhibition of wild type and drug resistant HIV-1 reverse transcriptase by fragment library screening.
Matthis Geitmann, Malin Elinder, Christian Seeger, Peter Brandt, Iwan J P de Esch

J Med Chem· February 2011

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Experimental validation of a fragment library for lead discovery using SPR biosensor technology.
Malin Elinder, Matthis Geitmann, Thomas Gossas, Per Källblad, Johan Winquist

J Biomol Screen· January 2011

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Development of surface plasmon resonance biosensor assays for primary and secondary screening of acetylcholine binding protein ligands.
Kim Retra, Matthis Geitmann, Jeroen Kool, August B Smit, Iwan J P de Esch

Anal Biochem· December 2010

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Surface plasmon resonance biosensor based fragment screening using acetylcholine binding protein identifies ligand efficiency hot spots (LE hot spots) by deconstruction of nicotinic acetylcholine receptor α7 ligands.
Gerdien E de Kloe, Kim Retra, Matthis Geitmann, Per Källblad, Tariq Nahar

J Med Chem· October 2010

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Interaction kinetic and structural dynamic analysis of ligand binding to acetylcholine-binding protein.
Matthis Geitmann, Kim Retra, Gerdien E de Kloe, Evert Homan, August B Smit

Biochemistry· September 2010

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Structural and functional analysis of hepatitis C virus strain JFH1 polymerase.
Philip Simister, Melanie Schmitt, Matthis Geitmann, Oliver Wicht, U Helena Danielson

J Virol· November 2009

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A protein interaction node at the neurotransmitter release site: domains of Aczonin/Piccolo, Bassoon, CAST, and rim converge on the N-terminal domain of Munc13-1.
Xiaolu Wang, Bin Hu, Agata Zieba, Nicole G Neumann, Monika Kasper-Sonnenberg, Matthis Geitmann

J Neurosci· October 2009

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Screening for NNRTIs with slow dissociation and high affinity for a panel of HIV-1 RT variants.
Malin Elinder, Helena Nordström, Matthis Geitmann, Markku Hämäläinen, Lotta Vrang

J Biomol Screen· April 2009

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Additional level of information about complex interaction between non-nucleoside inhibitor and HIV-1 reverse transcriptase using biosensor-based thermodynamic analysis.
Matthis Geitmann, U Helena Danielson

Bioorg Med Chem· December 2007

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Biomolecular recognition of glycosylated beta(3)-peptides by GalNAc specific lectins.
Anna S Norgren, Matthis Geitmann, U Helena Danielson, Per I Arvidsson

J Mol Recognit· August 2007

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Biosensor-based kinetic characterization of the interaction between HIV-1 reverse transcriptase and non-nucleoside inhibitors.
Matthis Geitmann, Torsten Unge, U Helena Danielson

J Med Chem· April 2006

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Interaction kinetic characterization of HIV-1 reverse transcriptase non-nucleoside inhibitor resistance.
Matthis Geitmann, Torsten Unge, U Helena Danielson

J Med Chem· April 2006

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Studies of substrate-induced conformational changes in human cytomegalovirus protease using optical biosensor technology.
Matthis Geitmann, U Helena Danielson

Anal Biochem· September 2004

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