Publications by authors named "Anne Need"

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Modulation of TARP 8-Containing AMPA Receptors as a Novel Therapeutic Approach for Chronic Pain.
Kelly L Knopp, Rosa Maria A Simmons, Wenhong Guo, Benjamin L Adams, Kevin M Gardinier, Anne Need

J Pharmacol Exp Ther· June 2019

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Discovery of the First α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antagonist Dependent upon Transmembrane AMPA Receptor Regulatory Protein (TARP) γ-8.
Kevin M Gardinier, Douglas L Gernert, Warren J Porter, Jon K Reel, Paul L Ornstein, Anne B Need

J Med Chem· May 2016

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Identifying novel radiotracers for PET imaging of the brain: application of LC-MS/MS to tracer identification.
Vanessa Barth, Anne Need

ACS Chem Neurosci· December 2014

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Efficiency gains in tracer identification for nuclear imaging: can in vivo LC-MS/MS evaluation of small molecules screen for successful PET tracers?
Elizabeth M Joshi, Anne Need, John Schaus, Zhaogen Chen, Dana Benesh

ACS Chem Neurosci· December 2014

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Determining pharmacological selectivity of the kappa opioid receptor antagonist LY2456302 using pupillometry as a translational biomarker in rat and human.
Linda M Rorick-Kehn, Jennifer W Witcher, Stephen L Lowe, Celedon R Gonzales, Mary Ann Weller, Anne B Need

Int J Neuropsychopharmacol· October 2014

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An Improved Antagonist Radiotracer for the κ-Opioid Receptor: Synthesis and Characterization of (11)C-LY2459989.
Ming-Qiang Zheng, Su Jin Kim, Daniel Holden, Shu-fei Lin, Anne Need

J Nucl Med· July 2014

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LLY-2707, a novel nonsteroidal glucocorticoid antagonist that reduces atypical antipsychotic-associated weight gain in rats.
Dana K Sindelar, Mathew W Carson, Michelle Morin, Janice Shaw, Robert J Barr, Anne Need

J Pharmacol Exp Ther· January 2014

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Glucose metabolic trapping in mouse arteries: nonradioactive assay of atherosclerotic plaque inflammation applicable to drug discovery.
Richard G Conway, Eyassu Chernet, David C De Rosa, Robert J Benschop, Anne B Need

PLoS One· June 2013

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In vivo rat brain opioid receptor binding of LY255582 assessed with a novel method using LC/MS/MS and the administration of three tracers simultaneously.
Anne B Need, Jamie H McKinzie, Charles H Mitch, Michael A Statnick, Lee A Phebus

Life Sci· October 2007

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Analgesic effects of serotonergic, noradrenergic or dual reuptake inhibitors in the carrageenan test in rats: evidence for synergism between serotonergic and noradrenergic reuptake inhibition.
Carrie K Jones, Brian J Eastwood, Anne B Need, Harlan E Shannon

Neuropharmacology· December 2006

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Metabotropic glutamate 5 receptor antagonism is associated with antidepressant-like effects in mice.
Xia Li, Anne B Need, Melvyn Baez, Jeffrey M Witkin

J Pharmacol Exp Ther· October 2006

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Comparison of rat dopamine D2 receptor occupancy for a series of antipsychotic drugs measured using radiolabeled or nonlabeled raclopride tracer.
Vanessa N Barth, Eyassu Chernet, Laura J Martin, Anne B Need, Karen S Rash

Life Sci· May 2006

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The relationship of in vivo central CB1 receptor occupancy to changes in cortical monoamine release and feeding elicited by CB1 receptor antagonists in rats.
Anne B Need, Richard J Davis, Jesline T Alexander-Chacko, Brian Eastwood, Eyassu Chernet

Psychopharmacology (Berl)· January 2006

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Use of LC/MS to assess brain tracer distribution in preclinical, in vivo receptor occupancy studies: dopamine D2, serotonin 2A and NK-1 receptors as examples.
Eyassu Chernet, Laura J Martin, Dominic Li, Anne B Need, Vanessa N Barth

Life Sci· December 2005

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Enhancement of antidepressant potency by a potentiator of AMPA receptors.
Xia Li, Jeffrey M Witkin, Anne B Need, Phil Skolnick

Cell Mol Neurobiol· June 2003

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