Publications by authors named "Anthony D Baughn"

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Retro-inversion imparts antimycobacterial specificity to host defense peptides.
Hugh D Glossop, Gebremichal Gebretsadik, Sabiha Sultana, Diptomit Biswas, Nathan A Schacht, Anthony D Baughn

Nat Commun· December 2025

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Essential role of MHC II in the antitubercular efficacy of pyrazinamide.
Elise A Lamont, Shannon L Kordus, Michael D Howe, Ziyi Jia, Nathan Schacht, Anthony D Baughn

Antimicrob Agents Chemother· December 2025

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Functional genomics reveals strain-specific genetic requirements conferring hypoxic growth in .
Yoshitaka Tateishi, Yuriko Ozeki, Akihito Nishiyama, Yuta Morishige, Yusuke Minato, Anthony David Baughn

Elife· December 2025

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In vitro investigation of Datura innoxia phytocompounds against Mycobacterium tuberculosis H37Ra strain in association with in silico studies.
Sajjad Ahmed Khan, Muzafar Ahmad Rather, Ziyi Jia, Muhammad Umer Khan, Syed Mehmood Qadir, Anthony D Baughn

Sci Rep· September 2025

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Structure-Guided Development of a Potent BioA Inhibitor Validates Biotin Synthesis Inhibition as a Therapeutic Strategy for Tuberculosis.
Qiang Liu, Joshua B Wallach, Yahani P Jayasinghe, Mark R Sullivan, Julianna Proietto, Anthony D Baughn

bioRxiv· September 2025

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Discovery of antitubercular potential of trans-3-indoleacrylic acid and its derivatives targeting Mycobacterium tuberculosis: A combined in vitro and in silico investigation.
Sajjad Ahmed Khan, Muzafar Ahmad Rather, Ziyi Jia, Syed Mehmood Qadir, Muhammad Umer Khan, Anthony D Baughn

Bioorg Chem· August 2025

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Mechanism of the dual action self-potentiating antitubercular drug morphazinamide.
Lev Ostrer, Taylor A Crooks, Michael D Howe, Sang Vo, Ziyi Jia, Anthony D Baughn

PNAS Nexus· August 2025

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Essential Role of MHC II in the Antitubercular Efficacy of Pyrazinamide.
Elise A Lamont, Shannon L Kordus, Michael D Howe, Ziyi Jia, Nathan Schacht, Anthony D Baughn

bioRxiv· August 2025

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Identification of as a potential source of antimycobacterial components.
Sajjad Ahmed Khan, Muzafar Ahmad Rather, Muhammad Sheeraz Ahmad, Ziyi Jia, Anthony D Baughn

Front Microbiol· July 2025

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A -Translation Inhibitor is Potentiated by Zinc and Kills and Nontuberculous Mycobacteria.
Akanksha Varshney, Ziyi Jia, Michael D Howe, Kenneth C Keiler, Anthony D Baughn

ACS Infect Dis· May 2025

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Lead Informed Artificial Intelligence Mining of Antitubercular Host Defense Peptides.
Diptomit Biswas, Sara Benson, Aidan Matunis, Gebremichal Gebretsadik, Adam Wertz, Anthony D Baughn

Biomacromolecules· May 2025

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Mechanism of the Dual Action Self-Potentiating Antitubercular Drug Morphazinamide.
Lev Ostrer, Taylor A Crooks, Michael D Howe, Sang Vo, Ziyi Jia, Anthony D Baughn

bioRxiv· January 2025

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Oxidative stress drives potent bactericidal activity of pyrazinamide against .
Nicholas A Dillon, Elise A Lamont, Muzafar A Rather, Anthony D Baughn

bioRxiv· December 2024

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A -translation inhibitor is potentiated by zinc and kills and non-tuberculous mycobacteria.
Akanksha Varshney, Ziyi Jia, Michael D Howe, Kenneth C Keiler, Anthony D Baughn

bioRxiv· November 2024

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Unique genomic sequences in a novel subsp. lineage enable fine scale transmission route tracing during pig movement.
Tetsuya Komatsu, Kenji Ohya, Atsushi Ota, Yukiko Nishiuchi, Hirokazu Yano, Anthony D Baughn

One Health· June 2023

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A Nucleophilic Activity-Based Probe Enables Profiling of PLP-Dependent Enzymes.
Scott I Brody, Joseph A Buonomo, Moyosore O Orimoloye, Ziyi Jia, Sachin Sharma, Anthony D Baughn

Chembiochem· April 2023

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Cephem-Pyrazinoic Acid Conjugates: Circumventing Resistance in Mycobacterium tuberculosis.
Malcolm S Cole, Michael D Howe, Joseph A Buonomo, Sachin Sharma, Elise A Lamont, Anthony D Baughn

Chemistry· September 2022

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Discovery and Optimization of 6-(1-Substituted pyrrole-2-yl)--triazine Containing Compounds as Antibacterial Agents.
Keith D Green, Allan H Pang, Nishad Thamban Chandrika, Atefeh Garzan, Anthony D Baughn

ACS Infect Dis· April 2022

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Synthesis and biological evaluation of orally active prodrugs and analogs of para-aminosalicylic acid (PAS).
Pooja V Hegde, Michael D Howe, Matthew D Zimmerman, Helena I M Boshoff, Sachin Sharma, Anthony D Baughn

Eur J Med Chem· March 2022

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Structure-Aware Mycobacterium tuberculosis Functional Annotation Uncloaks Resistance, Metabolic, and Virulence Genes.
Samuel J Modlin, Afif Elghraoui, Deepika Gunasekaran, Alyssa M Zlotnicki, Nicholas A Dillon, Anthony D Baughn

mSystems· December 2021

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Genomic features of subsp. isolated from pigs in Japan.
Tetsuya Komatsu, Kenji Ohya, Atsushi Ota, Yukiko Nishiuchi, Hirokazu Yano, Anthony D Baughn

GigaByte· November 2021

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Pathogen-specific antimicrobials engineered de novo through membrane-protein biomimicry.
Andrew W Simonson, Agustey S Mongia, Matthew R Aronson, John N Alumasa, Dennis C Chan, Anthony D Baughn

Nat Biomed Eng· May 2021

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Pyrazinamide Susceptibility Is Driven by Activation of the SigE-Dependent Cell Envelope Stress Response in Mycobacterium tuberculosis.
Joshua M Thiede, Nicholas A Dillon, Michael D Howe, Ranee Aflakpui, Samuel J Modlin, Anthony D Baughn

mBio· February 2021

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The Bewildering Antitubercular Action of Pyrazinamide.
Elise A Lamont, Nicholas A Dillon, Anthony D Baughn

Microbiol Mol Biol Rev· May 2020

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Genome-wide identification of essential genes in Mycobacterium intracellulare by transposon sequencing - Implication for metabolic remodeling.
Yoshitaka Tateishi, Yusuke Minato, Anthony D Baughn, Hiroaki Ohnishi, Akihito Nishiyama

Sci Rep· March 2020

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