Publications by authors named "Michael D Howe"

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Essential role of MHC II in the antitubercular efficacy of pyrazinamide.
Elise A Lamont, Shannon L Kordus, Michael D Howe, Ziyi Jia, Nathan Schacht

Antimicrob Agents Chemother· December 2025

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Mechanism of the dual action self-potentiating antitubercular drug morphazinamide.
Lev Ostrer, Taylor A Crooks, Michael D Howe, Sang Vo, Ziyi Jia

PNAS Nexus· August 2025

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Essential Role of MHC II in the Antitubercular Efficacy of Pyrazinamide.
Elise A Lamont, Shannon L Kordus, Michael D Howe, Ziyi Jia, Nathan Schacht

bioRxiv· August 2025

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A -Translation Inhibitor is Potentiated by Zinc and Kills and Nontuberculous Mycobacteria.
Akanksha Varshney, Ziyi Jia, Michael D Howe, Kenneth C Keiler, Anthony D Baughn

ACS Infect Dis· May 2025

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Mechanism of the Dual Action Self-Potentiating Antitubercular Drug Morphazinamide.
Lev Ostrer, Taylor A Crooks, Michael D Howe, Sang Vo, Ziyi Jia

bioRxiv· January 2025

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A -translation inhibitor is potentiated by zinc and kills and non-tuberculous mycobacteria.
Akanksha Varshney, Ziyi Jia, Michael D Howe, Kenneth C Keiler, Anthony D Baughn

bioRxiv· November 2024

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Cephem-Pyrazinoic Acid Conjugates: Circumventing Resistance in Mycobacterium tuberculosis.
Malcolm S Cole, Michael D Howe, Joseph A Buonomo, Sachin Sharma, Elise A Lamont

Chemistry· September 2022

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Synthesis and biological evaluation of orally active prodrugs and analogs of para-aminosalicylic acid (PAS).
Pooja V Hegde, Michael D Howe, Matthew D Zimmerman, Helena I M Boshoff, Sachin Sharma

Eur J Med Chem· March 2022

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Pathogen-specific antimicrobials engineered de novo through membrane-protein biomimicry.
Andrew W Simonson, Agustey S Mongia, Matthew R Aronson, John N Alumasa, Dennis C Chan, Michael D Howe

Nat Biomed Eng· May 2021

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Pyrazinamide Susceptibility Is Driven by Activation of the SigE-Dependent Cell Envelope Stress Response in Mycobacterium tuberculosis.
Joshua M Thiede, Nicholas A Dillon, Michael D Howe, Ranee Aflakpui, Samuel J Modlin

mBio· February 2021

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Methionine Antagonizes -Aminosalicylic Acid Activity via Affecting Folate Precursor Biosynthesis in .
Michael D Howe, Shannon L Kordus, Malcolm S Cole, Allison A Bauman, Courtney C Aldrich

Front Cell Infect Microbiol· September 2019

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Investigation of ( S)-(-)-Acidomycin: A Selective Antimycobacterial Natural Product That Inhibits Biotin Synthase.
Matthew R Bockman, Curtis A Engelhart, Julia D Cramer, Michael D Howe, Neeraj K Mishra

ACS Infect Dis· April 2019

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