Publications by authors named "April D Pyle"

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Transcytotic transportation of size-controlled nanocarriers into dystrophic skeletal muscle leads to therapeutic outcome in mice.
Xiangsheng Liu, Michael R Hicks, Zhenhan Feng, Jinhong Jiang, Yuting Li, April D Pyle

Nat Commun· December 2025

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Old World alphaviruses use distinct mechanisms to infect brain microvascular endothelial cells for neuroinvasion.
Pablo A Alvarez, Ashley Tang, Declan M Winters, Prashant Kaushal, Angelica Medina, April D Pyle

Cell Rep· October 2025

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Macrophage-derived Spp1 promotes intramuscular fat in dystrophic muscle.
Philip K Farahat, Chino Kumagai-Cresse, Raquel L Aragón, Feiyang Ma, Justin K Amakor, April D Pyle

JCI Insight· July 2025

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Old World alphaviruses use distinct mechanisms to infect brain microvascular endothelial cells for neuroinvasion.
Pablo A Alvarez, Ashley Tang, Declan M Winters, Prashant Kaushal, Angelica Medina, April D Pyle

bioRxiv· January 2025

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Publisher Correction: Regenerating human skeletal muscle forms an emerging niche in vivo to support PAX7 cells.
Michael R Hicks, Kholoud K Saleh, Ben Clock, Devin E Gibbs, Mandee Yang, April D Pyle

Nat Cell Biol· February 2024

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Regenerating human skeletal muscle forms an emerging niche in vivo to support PAX7 cells.
Michael R Hicks, Kholoud K Saleh, Ben Clock, Devin E Gibbs, Mandee Yang, April D Pyle

Nat Cell Biol· December 2023

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'Enhancing' skeletal muscle and stem cells in three-dimensions: genome regulation of skeletal muscle in development and disease.
Matthew A Romero, April D Pyle

Curr Opin Genet Dev· December 2023

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Innate and adaptive AAV-mediated immune responses in a mouse model of Duchenne muscular dystrophy.
Michael R Emami, Alejandro Espinoza, Courtney S Young, Feiyang Ma, Philip K Farahat, April D Pyle

Mol Ther Methods Clin Dev· September 2023

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Nanoparticles systemically biodistribute to regenerating skeletal muscle in DMD.
Michael R Hicks, Xiangsheng Liu, Courtney S Young, Kholoud Saleh, Ying Ji, April D Pyle

J Nanobiotechnology· August 2023

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SIX1+PAX3+ identify a progenitor for myogenic lineage commitment from hPSCs.
Olga G Jaime, Jessica Arias, Shreya Pavani, April D Pyle, Michael R Hicks

Development· July 2023

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Muscle fusogens go viral for gene delivery to skeletal muscle.
Devin E Gibbs, April D Pyle

Cell· May 2023

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Duchenne muscular dystrophy disease severity impacts skeletal muscle progenitor cells systemic delivery.
Kholoud K Saleh, Corey Switzler, Michael R Hicks, Lily Gane, Devin E Gibbs, April D Pyle

Front Physiol· May 2023

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Myoscaffolds reveal laminin scarring is detrimental for stem cell function while sarcospan induces compensatory fibrosis.
Kristen M Stearns-Reider, Michael R Hicks, Katherine G Hammond, Joseph C Reynolds, Alok Maity, April D Pyle

NPJ Regen Med· March 2023

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The emergence of the stem cell niche.
Michael R Hicks, April D Pyle

Trends Cell Biol· February 2023

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Single cell sequencing maps skeletal muscle cellular diversity as disease severity increases in dystrophic mouse models.
Kholoud K Saleh, Haibin Xi, Corey Switzler, Emily Skuratovsky, Matthew A Romero, April D Pyle

iScience· November 2022

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Single-cell analysis and functional characterization uncover the stem cell hierarchies and developmental origins of rhabdomyosarcoma.
Yun Wei, Qian Qin, Chuan Yan, Madeline N Hayes, Sara P Garcia, April D Pyle

Nat Cancer· August 2022

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Recapitulating human myogenesis ex vivo using human pluripotent stem cells.
Peggie Chien, Haibin Xi, April D Pyle

Exp Cell Res· February 2022

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CRISPR-Mediated Genomic Addition to CPS1 Deficient iPSCs is Insufficient to Restore Nitrogen Homeostasis.
Matthew Nitzahn, Brian Truong, Suhail Khoja, Agustin Vega-Crespo, Colleen Le, April D Pyle

Yale J Biol Med· December 2021

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Long-term repair of porcine articular cartilage using cryopreservable, clinically compatible human embryonic stem cell-derived chondrocytes.
Frank A Petrigliano, Nancy Q Liu, Siyoung Lee, Jade Tassey, Arijita Sarkar, April D Pyle

NPJ Regen Med· November 2021

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Symmetry breaking of tissue mechanics in wound induced hair follicle regeneration of laboratory and spiny mice.
Hans I-Chen Harn, Sheng-Pei Wang, Yung-Chih Lai, Ben Van Handel, Ya-Chen Liang, April D Pyle

Nat Commun· May 2021

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Genome Editing-Mediated Utrophin Upregulation in Duchenne Muscular Dystrophy Stem Cells.
Kasturi Sengupta, Manoj K Mishra, Emanuele Loro, Melissa J Spencer, April D Pyle

Mol Ther Nucleic Acids· December 2020

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Generation of PAX7 Reporter Cells to Investigate Skeletal Myogenesis from Human Pluripotent Stem Cells.
Haibin Xi, Courtney S Young, April D Pyle

STAR Protoc· December 2020

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A Small-Molecule Approach to Restore a Slow-Oxidative Phenotype and Defective CaMKIIβ Signaling in Limb Girdle Muscular Dystrophy.
Jian Liu, Jesus Campagna, Varghese John, Robert Damoiseaux, Ekaterina Mokhonova, April D Pyle

Cell Rep Med· October 2020

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A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem Cells.
Haibin Xi, Justin Langerman, Shan Sabri, Peggie Chien, Courtney S Young, April D Pyle

Cell Stem Cell· July 2020

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A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem Cells.
Haibin Xi, Justin Langerman, Shan Sabri, Peggie Chien, Courtney S Young, April D Pyle

Cell Stem Cell· July 2020

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