Publications by authors named "April Xu"

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Photostability of Topoisomerase I Inhibitor Conjugated IgG1 Antibody-Drug Conjugates: Characterization Study and Degradation Mechanism Analysis.
Ting Zhou, Xinmei Dong, Jiayi Yu, Chengcheng Song, Qinyi Liu, April Xu

Bioconjug Chem· December 2025

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Augmenting therapeutic protein production in CHO cells: A proline-based selection strategy for enhanced productivity and product quality.
Bin Zhao, Boya Zhang, Yanshen Kang, Shenghai Liu, Zhangying Jia, April Xu

Biotechnol Prog· November 2025

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Tailoring Plasmid Design Based on Chain Expression in Cell Line Development for Enhanced Monoclonal and Bispecific Antibody Production.
Shenghai Liu, Qianqian Chen, Lujia Peng, Hongli Li, Bin Zhao, Xuefeng Guo, April Xu

Biotechnol J· August 2025

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Simultaneous Analysis of the Drug-to-Antibody Ratio, Free-Drug-Related Impurities, and Purity of Antibody-Drug Conjugates Based on Size Exclusion Chromatography.
Woran Song, Lifeng Yin, Jun Ren, Lai Jiang, Zi-Ao Huang, April Xu

Anal Chem· May 2025

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Estimated median density identifies donor age and sex differences in red blood cell biological age.
Olga Mykhailova, Mackenzie Brandon-Coatham, Kiarra Durand, Carly Olafson, April Xu

Transfusion· April 2024

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Accelerating the speed of innovative anti-tumor drugs to first-in-human trials incorporating key de-risk strategies.
Yuqi Wang, Quan Quan, Camille Gleason, Helin Yu, Lujia Peng, Bin Xu, April Xu

MAbs· December 2023

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Identification and characterization of an unexpected isomerization motif in CDRH2 that affects antibody activity.
Meiqi Yi, Jian Sun, Hanzi Sun, Yifei Wang, Shan Hou, Liu Xue, April Xu

MAbs· May 2023

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Evaluating blood product quality post expiry to mitigate blood shortages during the COVID-19 pandemic in Canada.
Tracey R Turner, Carly Olafson, Olga Mykhailova, April Xu, Jason P Acker

Transfusion· December 2020

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Efficient and Selective Bioconjugation Using Surfactants.
Xi Hu, Thomas F Lerch, April Xu

Bioconjug Chem· November 2018

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[The Characterization of Drug-to-Antibody Ratio and Isoforms of ADCs Using LC and MS Technologies].
Reiko Iizuka, Frank Kotch, April Xu, Thomas Porter, Henry Shion

Yakugaku Zasshi· August 2017

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A rapid on-line method for mass spectrometric confirmation of a cysteine-conjugated antibody-drug-conjugate structure using multidimensional chromatography.
Robert E Birdsall, Henry Shion, Frank W Kotch, April Xu, Thomas J Porter

MAbs· August 2016

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Fully Mechanically Controlled Automated Electron Microscopic Tomography.
Jinxin Liu, Hongchang Li, Lei Zhang, Matthew Rames, Meng Zhang, April Xu, Xu Yang, Xuefeng Chen

Sci Rep· July 2016

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World Antibody-Drug Conjugate Summit, October 15-16, 2013, San Francisco, CA.
Christine Klinguer-Hamour, Pavel Strop, Dhaval K Shah, Laurent Ducry, April Xu

MAbs· October 2014

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Migration, proliferation, and differentiation of cord blood mesenchymal stromal cells treated with histone deacetylase inhibitor valproic Acid.
Leah A Marquez-Curtis, Yuanyuan Qiu, April Xu, Anna Janowska-Wieczorek

Stem Cells Int· April 2014

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Angiopoietins have distinct modular domains essential for receptor binding, dimerization and superclustering.
Samuel Davis, Nick Papadopoulos, Thomas H Aldrich, Peter C Maisonpierre, Tammy Huang, April Xu

Nat Struct Biol· January 2003

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