Publications by authors named "Aram Hezel"

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A Reassessment of the Clinical Utility of Ga-DOTATATE PET/CT in Patients With Gastroenteropancreatic Neuroendocrine Tumors.
Orjola Prela, Brennen Caveney, Myla Strawderman, David Linehan, Eva Galka, Aram Hezel

J Surg Oncol· June 2025

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Neoadjuvant pemigatinib as a bridge to living donor liver transplantation for intrahepatic cholangiocarcinoma with FGFR2 gene rearrangement.
Matthew M Byrne, Richard F Dunne, Jennifer I Melaragno, Mariana Chávez-Villa, Aram Hezel

Am J Transplant· March 2025

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Glutathione synthesis in the mouse liver supports lipid abundance through NRF2 repression.
Gloria Asantewaa, Emily T Tuttle, Nathan P Ward, Yun Pyo Kang, Yumi Kim, Aram F Hezel

Nat Commun· July 2024

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Smad4 restricts injury-provoked biliary proliferation and carcinogenesis.
William B Alexander, Wenjia Wang, Margaret A Hill, Michael R O'Dell, Luis I Ruffolo, Aram F Hezel

Dis Model Mech· June 2024

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SWI/SNF chromatin remodeling complex in pancreatic ductal adenocarcinoma: Clinicopathologic and immunohistochemical study.
Irene Y Chen, Mark G Ettel, Phoenix D Bell, Aaron R Huber, Jennifer J Findeis-Hosey, Aram F Hezel

Hum Pathol· February 2024

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Organ Preservation and Survival by Clinical Response Grade in Patients With Rectal Cancer Treated With Total Neoadjuvant Therapy: A Secondary Analysis of the OPRA Randomized Clinical Trial.
Hannah M Thompson, Dana M Omer, Sabrina Lin, Jin K Kim, Jonathan B Yuval, Aram F Hezel

JAMA Netw Open· January 2024

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Netrin-1 feedforward mechanism promotes pancreatic cancer liver metastasis via hepatic stellate cell activation, retinoid, and ELF3 signaling.
Crissy Dudgeon, Anthony Casabianca, Chris Harris, Charline Ogier, Mélanie Bellina, Aram Hezel

Cell Rep· November 2023

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Spatially Resolved Single-Cell Assessment of Pancreatic Cancer Expression Subtypes Reveals Co-expressor Phenotypes and Extensive Intratumoral Heterogeneity.
Hannah L Williams, Andressa Dias Costa, Jinming Zhang, Srivatsan Raghavan, Peter S Winter, Aram F Hezel

Cancer Res· February 2023

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Glutathione supports lipid abundance .
Gloria Asantewaa, Emily T Tuttle, Nathan P Ward, Yun Pyo Kang, Yumi Kim, Aram F Hezel

bioRxiv· February 2023

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Neoadjuvant Chemotherapy Is Associated with Altered Immune Cell Infiltration and an Anti-Tumorigenic Microenvironment in Resected Pancreatic Cancer.
Andressa Dias Costa, Sara A Väyrynen, Akhil Chawla, Jinming Zhang, Juha P Väyrynen, Aram F Hezel

Clin Cancer Res· December 2022

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Arid1a mutation suppresses TGF-β signaling and induces cholangiocarcinoma.
Bing Guo, Scott C Friedland, William Alexander, Jacquelyn A Myers, Wenjia Wang, Aram F Hezel

Cell Rep· August 2022

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GM-CSF drives myelopoiesis, recruitment and polarisation of tumour-associated macrophages in cholangiocarcinoma and systemic blockade facilitates antitumour immunity.
Luis I Ruffolo, Katherine M Jackson, Peyton C Kuhlers, Benjamin S Dale, Nathania M Figueroa Guilliani, Aram F Hezel

Gut· July 2022

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Prevalence of and factors associated with treatment modification at first cycle in older adults with advanced cancer receiving palliative treatment.
Mostafa R Mohamed, Kaitlin Kyi, Supriya G Mohile, Huiwen Xu, Eva Culakova, Aram Hezel

J Geriatr Oncol· November 2021

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FOSL1 promotes cholangiocarcinoma via transcriptional effectors that could be therapeutically targeted.
Adrián Vallejo, Oihane Erice, Rodrigo Entrialgo-Cadierno, Iker Feliu, Elizabeth Guruceaga, Aram F Hezel

J Hepatol· August 2021

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Composition, Spatial Characteristics, and Prognostic Significance of Myeloid Cell Infiltration in Pancreatic Cancer.
Sara A Väyrynen, Jinming Zhang, Chen Yuan, Juha P Väyrynen, Andressa Dias Costa, Aram F Hezel

Clin Cancer Res· February 2021

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Adjuvant Chemotherapy Use in Patients With Locally Advanced Rectal Cancer: A Single-Institution Experience.
Franklin Li, Gradon Nielsen, Andrea Baran, John Hu, Danielle Wallace, Aram F Hezel

Clin Colorectal Cancer· September 2020

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Insulin-Like Growth Factor-1 Receptor Expression and Disease Recurrence and Survival in Patients with Resected Pancreatic Ductal Adenocarcinoma.
Chunxia Du, Annacarolina da Silva, Vicente Morales-Oyarvide, Andressa Dias Costa, Margaret M Kozak, Aram F Hezel

Cancer Epidemiol Biomarkers Prev· August 2020

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Endocrine-Exocrine Signaling Drives Obesity-Associated Pancreatic Ductal Adenocarcinoma.
Katherine Minjee Chung, Jaffarguriqbal Singh, Lauren Lawres, Kimberly Judith Dorans, Cathy Garcia, Aram F Hezel

Cell· May 2020

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Durvalumab With or Without Tremelimumab for Patients With Metastatic Pancreatic Ductal Adenocarcinoma: A Phase 2 Randomized Clinical Trial.
Eileen M O'Reilly, Do-Youn Oh, Neesha Dhani, Daniel J Renouf, Myung Ah Lee, Aram Hezel

JAMA Oncol· October 2019

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ARID1A, a SWI/SNF subunit, is critical to acinar cell homeostasis and regeneration and is a barrier to transformation and epithelial-mesenchymal transition in the pancreas.
Wenjia Wang, Scott C Friedland, Bing Guo, Michael R O'Dell, William B Alexander, Aram F Hezel

Gut· July 2019

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Germline cancer susceptibility gene variants, somatic second hits, and survival outcomes in patients with resected pancreatic cancer.
Matthew B Yurgelun, Anu B Chittenden, Vicente Morales-Oyarvide, Douglas A Rubinson, Richard F Dunne, Aram F Hezel

Genet Med· January 2019

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and Mutations Cause Cholangiocyte- and Hepatocyte-Derived Cholangiocarcinoma.
Margaret A Hill, William B Alexander, Bing Guo, Yasutaka Kato, Krushna Patra, Aram F Hezel

Cancer Res· August 2018

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Beyond microsatellite testing: assessment of tumor mutational burden identifies subsets of colorectal cancer who may respond to immune checkpoint inhibition.
David A Fabrizio, Thomas J George, Richard F Dunne, Garrett Frampton, James Sun, Aram F Hezel

J Gastrointest Oncol· August 2018

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Cetuximab Combined With Induction Oxaliplatin and Capecitabine, Followed by Neoadjuvant Chemoradiation for Locally Advanced Rectal Cancer: SWOG 0713.
Cynthia Gail Leichman, Shannon L McDonough, Stephen R Smalley, Kevin G Billingsley, Heinz-Josef Lenz, Aram F Hezel

Clin Colorectal Cancer· March 2018

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Serum Response Factor Is Essential for Maintenance of Podocyte Structure and Function.
Bing Guo, Qing Lyu, Orazio J Slivano, Ronald Dirkx, Christine K Christie, Aram F Hezel

J Am Soc Nephrol· February 2018

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