Publications by authors named "Arvind Mathur"

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Development and validation of a deprescribing tool relevant to older persons in India using modified Delphi consensus technique.
Ratinder Jhaj, Atiya R Faruqui, Santanu Kumar Tripathi, Minakshi Dhar, Rajnish Joshi, Arvind Mathur

BMC Geriatr· December 2025

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Desymmetrization of -Anhydride Enabled Enantioselective Synthesis of (-)-7-(Bromomethylene)-3-amidobicyclo[2.2.1]heptane-2-carboxamide, a Scaffold for Divergent Drug Discovery Synthesis.
Jianqing Li, Subramaniam Krishnananthan, Daniel Smith, Chetan Padmakar Darne, Ning Li, Arvind Mathur

J Org Chem· December 2025

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Teaching Clinical Reasoning Through Cause-and-Effect Thinking: A Framework for Modern Medical Education.
Arvind Mathur

Clin Teach· October 2025

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Beyond Bioisosteres: Impact of Replacing a Benzene Ring with sp-Rich Three-Dimensional Saturated Bridged Bicyclic Match Pairs on Biotransformation, Metabolic Stability, and Other ADME Profiles.
Shruti Surendran, Sivashankaran Raju, Naveen Kalyani, Gaurav Saini, Joyson Nandha, Arvind Mathur

J Med Chem· October 2025

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Discovery of liver-selective glucokinase activators comprising N-(4-alkylthiazol-2-yl)benzamides and N-(3-alkyl-1,2,4-thiadiazol-5-yl)benzamides for the treatment of metabolic disorders.
David S Yoon, Shung Wu, Sean S Chen, Rebecca A Smirk, Robert P Brigance, Arvind Mathur

Bioorg Med Chem Lett· July 2025

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Application of 2D-liquid chromatography for the separation of a mixture of isomeric and structurally related azatryptophan derivatives.
Parinita Shaw, Pandidurai Sekar, Balasaheb Chavan, Sharad Duche, Arvind Mathur

Anal Methods· July 2025

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Discovery and Characterization of a First-in-Class LIV1-TLR7/8 Immunomodulatory Conjugate with Robust Myeloid Activation and Antitumor Activity.
Sayumi Yamazoe, Yam Poudel, Emanuela Sega, Anandaroop Mukhopadhyay, Radha Ramakrishnan, Arvind Mathur

J Med Chem· June 2025

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The Discovery of C7-Substituted Norbornyl Bisamides as RXFP1 Small Molecule Agonists.
Shun Su, Michael C Myers, Donna M Bilder, Adam Clarke, Todd Friends, Arvind Mathur

J Med Chem· June 2025

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Pallada-Electrocatalysis Enables Distal Regioselective and Atroposelective Olefination Reactions.
Subir Panja, Avishek Pan, Swastik Biswas, Chandan Das, Aritra Guha, Arvind Mathur

Angew Chem Int Ed Engl· April 2025

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2-Methyl tetrahydrofuran: a green organic modifier for eco-friendly, cost-effective, and rapid purification in drug discovery.
Vijayalakshmi Sathiyamoorthy, Khemraj Bairwa, Sharad Duche, Amrita Roy, Arvind Mathur

Anal Methods· April 2025

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Shapeshifting Gabriel Amine Synthesis with Iodo-BCPs.
Manivel Pitchai, Nanjundaswamy K C, Sankar Ulaganathan, Mohammad Javeed, Antonio Ramirez, Arvind Mathur

J Org Chem· March 2025

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Structure-Based Design of Novel TLR7/8 Agonist Payloads Enabling an Immunomodulatory Conjugate Approach.
Yam B Poudel, Julian C Lo, Derek J Norris, Matthew Cox, Liqi He, Arvind Mathur

ACS Med Chem Lett· January 2025

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Effect of Solvent on the Optical Rotation of Azatryptophan Derivatives.
Mitalee Das, Felix Kulandai, Hemantha Kumar, Prakasam Kuppuswamy, Bandreddy Subba, Arvind Mathur

Magn Reson Chem· December 2024

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Discovery and Synthesis of Heterobifunctional Degraders of Rearranged during Transfection (RET) Kinase.
Jennifer X Qiao, David Williams, Patrice Gill, Ling Li, Derek Norris, Arvind Mathur

J Med Chem· November 2024

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Prodrug Strategy to Address Impaired Oral Absorption of a Weakly Basic TYK2 Inhibitor Caused by a Gastric Acid-Reducing Agent.
Murugaiah A M Subbaiah, Thangeswaran Ramar, Maheswara Reddy, Sankara Sivaprasad Lvj, Shekhar Yeshwante, Arvind Mathur

J Med Chem· November 2024

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Large-scale purification of a deprotected macrocyclic peptide by supercritical fluid chromatography (SFC) integrated with liquid chromatography in discovery chemistry.
Peng Li, Dauh-Rurng Wu, Shiuhang Henry Yip, Dawn Sun, Joseph Pawluczyk, Arvind Mathur

J Chromatogr A· August 2024

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Synthesis of diversely substituted quinazoline-2,4(1,3)-diones by cyclization of -butyl (2-cyanoaryl)carbamates.
Satish Kovela, Somnath Karad, V V Ganesh Tatipudi, Karthikeyan Arumugam, Atul Vijay Somwanshi, Arvind Mathur

Org Biomol Chem· August 2024

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Atropisomerism Observed in Galactose-Based Monosaccharide Inhibitors of Galectin-3 Comprising 2-Methyl-4-phenyl-2,4-dihydro-3-1,2,4-triazole-3-thione.
David S Yoon, Chunjian Liu, Prasada Rao Jalagam, Jianxin Feng, Wei Wang, Arvind Mathur

J Med Chem· August 2024

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Discovery of BMS-986308: A Renal Outer Medullary Potassium Channel Inhibitor for the Treatment of Heart Failure.
Jeremy M Richter, Prashantha Gunaga, Navnath Yadav, Rajesh Onkardas Bora, Rajeev Bhide, Arvind Mathur

J Med Chem· June 2024

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Organic Photoredox-Catalyzed -Trifluoromethylation of Aromatic and Heteroaromatic Thiols.
Aditya Bhattacharyya, Veeresh Vadde, Manash Pratim Sarmah, M Muthukumar, Arvind Mathur

Org Lett· June 2024

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Challenges with the Synthesis of a Macrocyclic Thioether Peptide: From Milligram to Multigram Using Solid Phase Peptide Synthesis (SPPS).
James Kempson, Rulin Zhao, Joseph Pawluczyk, Bei Wang, Huiping Zhang, Arvind Mathur

J Org Chem· May 2024

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Identification of benzothiazole derived monosaccharides as potent, selective, and orally bioavailable inhibitors of human and mouse galectin-3; a rare example of using a S···O binding interaction for drug design.
Chunjian Liu, Wei Wang, Jianxin Feng, Brett Beno, Thiruvenkadam Raja, Arvind Mathur

Bioorg Med Chem· March 2024

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Discovery of Novel TLR7 Agonists as Systemic Agent for Combination With aPD1 for Use in Immuno-oncology.
Yam B Poudel, Liqi He, Matthew Cox, Qian Zhang, Walter L Johnson, Arvind Mathur

ACS Med Chem Lett· February 2024

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Identification and Optimization of Small Molecule Pyrazolopyrimidine TLR7 Agonists for Applications in Immuno-oncology.
Liqi He, Meng Yao Zhang, Matthew Cox, Qian Zhang, Andrew F Donnell, Arvind Mathur

ACS Med Chem Lett· February 2024

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The response to COVID-19 in Timor-Leste: lessons learnt.
Joshua R Francis, Rui Maria de Araujo, Odete da Silva Viegas, Sergio Lobo, Danina Coelho, Arvind Mathur

BMJ Glob Health· October 2023

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