Publications by authors named "Ashley Birkett"

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Value profile for Malaria vaccines and monoclonal antibodies.
Ashley J Birkett, Evelyn Ansah, Scott Gordon, Margaret Gyapong, Shanelle Hall

Vaccine· November 2025

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Analysis of the diverse antigenic landscape of the malaria protein RH5 identifies a potent vaccine-induced human public antibody clonotype.
Jordan R Barrett, Dimitra Pipini, Nathan D Wright, Andrew J R Cooper, Giacomo Gorini, Ashley J Birkett

Cell· September 2024

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Preclinical development of a stabilized RH5 virus-like particle vaccine that induces improved antimalarial antibodies.
Lloyd D W King, David Pulido, Jordan R Barrett, Hannah Davies, Doris Quinkert, Ashley J Birkett

Cell Rep Med· July 2024

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Development of an improved blood-stage malaria vaccine targeting the essential RH5-CyRPA-RIPR invasion complex.
Barnabas G Williams, Lloyd D W King, David Pulido, Doris Quinkert, Amelia M Lias, Ashley J Birkett

Nat Commun· June 2024

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Safety, tolerability, and Plasmodium falciparum transmission-reducing activity of monoclonal antibody TB31F: a single-centre, open-label, first-in-human, dose-escalation, phase 1 trial in healthy malaria-naive adults.
Saskia C van der Boor, Merel J Smit, Stijn W van Beek, Jordache Ramjith, Karina Teelen, Ashley J Birkett

Lancet Infect Dis· November 2022

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The Importance of Exercising Caution When Comparing Results from Malaria Vaccines Administered on the EPI Schedule and on a Seasonal Schedule.
Ashley Birkett, R Scott Miller, Lorraine A Soisson

Am J Trop Med Hyg· November 2022

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Combining antimalarial drugs and vaccine for malaria elimination campaigns: a randomized safety and immunogenicity trial of RTS,S/AS01 administered with dihydroartemisinin, piperaquine, and primaquine in healthy Thai adult volunteers.
Lorenz von Seidlein, Borimas Hanboonkunupakarn, Podjanee Jittamala, Pongphaya Pongsuwan, Kesinee Chotivanich, Ashley J Birkett

Hum Vaccin Immunother· March 2021

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An open-label phase 1/2a trial of a genetically modified rodent malaria parasite for immunization against malaria.
Isaie J Reuling, António M Mendes, Gerdie M de Jong, Amanda Fabra-García, Helena Nunes-Cabaço, Ashley J Birkett

Sci Transl Med· May 2020

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Expression of full-length Plasmodium falciparum P48/45 in P. berghei blood stages: A method to express and evaluate vaccine antigens.
Ahmad Syibli Othman, Jing-Wen Lin, Blandine M Franke-Fayard, Hans Kroeze, Fiona J A van Pul, Ashley Birkett

Mol Biochem Parasitol· September 2018

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Malaria vaccine candidate based on Duffy-binding protein elicits strain transcending functional antibodies in a Phase I trial.
Kavita Singh, Paushali Mukherjee, Ahmad Rushdi Shakri, Ankita Singh, Gaurav Pandey, Ashley Birkett

NPJ Vaccines· September 2018

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Malaria Derived Glycosylphosphatidylinositol Anchor Enhances Anti-Pfs25 Functional Antibodies That Block Malaria Transmission.
Neeraj Kapoor, Ivana Vanjak, James Rozzelle, Aym Berges, Wei Chan, Ashley J Birkett

Biochemistry· February 2018

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Vaccines to Accelerate Malaria Elimination and Eventual Eradication.
Julie Healer, Alan F Cowman, David C Kaslow, Ashley J Birkett

Cold Spring Harb Perspect Med· September 2017

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Fractional Third and Fourth Dose of RTS,S/AS01 Malaria Candidate Vaccine: A Phase 2a Controlled Human Malaria Parasite Infection and Immunogenicity Study.
Jason A Regules, Susan B Cicatelli, Jason W Bennett, Kristopher M Paolino, Patrick S Twomey, Ashley J Birkett

J Infect Dis· September 2016

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Demonstration of the Blood-Stage Plasmodium falciparum Controlled Human Malaria Infection Model to Assess Efficacy of the P. falciparum Apical Membrane Antigen 1 Vaccine, FMP2.1/AS01.
Ruth O Payne, Kathryn H Milne, Sean C Elias, Nick J Edwards, Alexander D Douglas, Ashley J Birkett

J Infect Dis· June 2016

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Status of vaccine research and development of vaccines for malaria.
Ashley J Birkett

Vaccine· June 2016

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Ad35.CS.01-RTS,S/AS01 Heterologous Prime Boost Vaccine Efficacy against Sporozoite Challenge in Healthy Malaria-Naïve Adults.
Christian F Ockenhouse, Jason Regules, Donna Tosh, Jessica Cowden, April Kathcart, Ashley Birkett

PLoS One· March 2016

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Phase 1/2a Trial of Plasmodium vivax Malaria Vaccine Candidate VMP001/AS01B in Malaria-Naive Adults: Safety, Immunogenicity, and Efficacy.
Jason W Bennett, Anjali Yadava, Donna Tosh, Jetsumon Sattabongkot, Jack Komisar, Ashley Birkett

PLoS Negl Trop Dis· February 2016

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A slot blot immunoassay for quantitative detection of Plasmodium falciparum circumsporozoite protein in mosquito midgut oocyst.
Sanjai Kumar, Hong Zheng, Bingbing Deng, Babita Mahajan, Bryan Grabias, Ashley Birkett

PLoS One· December 2015

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Building an effective malaria vaccine pipeline to address global needs.
Ashley J Birkett

Vaccine· December 2015

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A comparison of Plasmodium falciparum circumsporozoite protein-based slot blot and ELISA immuno-assays for oocyst detection in mosquito homogenates.
Will Stone, Bryan Grabias, Kjerstin Lanke, Hong Zheng, Emily Locke, Ashley Birkett

Malar J· November 2015

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Development of a transmission-blocking malaria vaccine: progress, challenges, and the path forward.
Julia K Nunes, Colleen Woods, Terrell Carter, Theresa Raphael, Merribeth J Morin, Ashley J Birkett

Vaccine· September 2014

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Mosquito feeding assays to determine the infectiousness of naturally infected Plasmodium falciparum gametocyte carriers.
Teun Bousema, Rhoel R Dinglasan, Isabelle Morlais, Louis C Gouagna, Travis van Warmerdam, Ashley Birkett

PLoS One· April 2013

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Malaria vaccine R&D in the Decade of Vaccines: breakthroughs, challenges and opportunities.
Ashley J Birkett, Vasee S Moorthy, Christian Loucq, Chetan E Chitnis, David C Kaslow

Vaccine· April 2013

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Aligning new interventions with developing country health systems: target product profiles, presentation, and clinical trial design.
Alan Brooks, Julia K Nunes, Andrew Garnett, Robin Biellik, Didier Leboulleux, Ashley J Birkett

Glob Public Health· February 2013

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Producing a successful malaria vaccine: innovation in the lab and beyond.
Christian Loucq, Ashley Birkett, David Poland, Carla Botting, Julia Nunes

Health Aff (Millwood)· June 2011

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