Publications by authors named "Assael A Madrigal"

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Neuronal aging causes mislocalization of splicing proteins and unchecked cellular stress.
Kevin Rhine, Rachel Li, Hema M Kopalle, Katherine Rothamel, Xuezhen Ge, Assael A Madrigal

Nat Neurosci· June 2025

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Genome-Wide Interrogation of SARS-CoV-2 RNA-Protein Interactions Uncovers Hidden Regulatory Sites.
Joy S Xiang, Karen X Zhao, Laliv Tadri, Kurt Tamaru, Brian A Yee, Assael A Madrigal

bioRxiv· May 2025

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Inhibition of RNA splicing triggers CHMP7 nuclear entry, impacting TDP-43 function and leading to the onset of ALS cellular phenotypes.
Norah Al-Azzam, Jenny H To, Vaishali Gautam, Lena A Street, Chloe B Nguyen, Assael A Madrigal

Neuron· December 2024

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Mapping the future of oxidative RNA damage in neurodegeneration: Rethinking the status quo with new tools.
Hailey B Wheeler, Assael A Madrigal, Isaac A Chaim

Proc Natl Acad Sci U S A· November 2024

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MECP2-related pathways are dysregulated in a cortical organoid model of myotonic dystrophy.
Kathryn H Morelli, Wenhao Jin, Shashank Shathe, Assael A Madrigal, Krysten L Jones

Sci Transl Med· June 2022

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Crosstalk between CRISPR-Cas9 and the human transcriptome.
Aaron A Smargon, Assael A Madrigal, Brian A Yee, Kevin D Dong, Jasmine R Mueller

Nat Commun· March 2022

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Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer.
Jaclyn M Einstein, Mark Perelis, Isaac A Chaim, Jitendra K Meena, Julia K Nussbacher, Assael A Madrigal

Mol Cell· August 2021

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Robust single-cell discovery of RNA targets of RNA-binding proteins and ribosomes.
Kristopher W Brannan, Isaac A Chaim, Ryan J Marina, Brian A Yee, Eric R Kofman, Assael A Madrigal

Nat Methods· May 2021

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Reintroduction of the archaic variant of in cortical organoids alters neurodevelopment.
Cleber A Trujillo, Edward S Rice, Nathan K Schaefer, Isaac A Chaim, Emily C Wheeler, Assael A Madrigal

Science· February 2021

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Peptide Brush Polymers for Efficient Delivery of a Gene Editing Protein to Stem Cells.
Angela P Blum, David A Nelles, Francisco J Hidalgo, Mollie A Touve, Deborah S Sim, Assael A Madrigal

Angew Chem Int Ed Engl· October 2019

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Transcriptome-pathology correlation identifies interplay between TDP-43 and the expression of its kinase CK1E in sporadic ALS.
Florian Krach, Ranjan Batra, Emily C Wheeler, Anthony Q Vu, Ruth Wang, Assael A Madrigal

Acta Neuropathol· September 2018

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