Publications by authors named "Avi Samelson"

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Multi-omic phenotyping of iPSC-derived neurons harboring the V337M mutation reveals tau hypophosphorylation and perturbed axon morphology pathways.
Gregory A Mohl, Gary Dixon, Emily Marzette, Justin McKetney, Avi J Samelson

bioRxiv· September 2025

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CRISPRi-based screens in iAssembloids to elucidate neuron-glia interactions.
Emmy Li, Camila Benitez, Steven C Boggess, Mark Koontz, Indigo V L Rose, Avi J Samelson

Neuron· March 2025

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CRISPRi-based screens in iAssembloids to elucidate neuron-glia interactions.
Emmy Li, Camila Benitez, Steven C Boggess, Mark Koontz, Indigo V L Rose, Avi J Samelson

bioRxiv· November 2024

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CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis.
Avi J Samelson, Nabeela Ariqat, Justin McKetney, Gita Rohanitazangi, Celeste Parra Bravo

bioRxiv· November 2024

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Human iPSC 4R tauopathy model uncovers modifiers of tau propagation.
Celeste Parra Bravo, Alice Maria Giani, Jesus Madero-Perez, Zeping Zhao, Yuansong Wan, Avi J Samelson

Cell· May 2024

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Human iPSC 4R tauopathy model uncovers modifiers of tau propagation.
Celeste Parra Bravo, Alice Maria Giani, Jesus Madero Perez, Zeping Zhao, Avi Samelson

bioRxiv· June 2023

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BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2.
Avi J Samelson, Quang Dinh Tran, Rémy Robinot, Lucia Carrau, Veronica V Rezelj

Nat Cell Biol· January 2022

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BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2.
Avi J Samelson, Quang Dinh Tran, Rémy Robinot, Lucia Carrau, Veronica V Rezelj

bioRxiv· September 2021

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Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing.
James K Nuñez, Jin Chen, Greg C Pommier, J Zachery Cogan, Joseph M Replogle, Avi J Samelson

Cell· April 2021

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The folding and unfolding behavior of ribonuclease H on the ribosome.
Madeleine K Jensen, Avi J Samelson, Annette Steward, Jane Clarke, Susan Marqusee

J Biol Chem· August 2020

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Comparing serial X-ray crystallography and microcrystal electron diffraction (MicroED) as methods for routine structure determination from small macromolecular crystals.
Alexander M Wolff, Iris D Young, Raymond G Sierra, Aaron S Brewster, Michael W Martynowycz, Avi J Samelson

IUCrJ· March 2020

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Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex.
Rosalie E Lawrence, Simon A Fromm, Yangxue Fu, Adam L Yokom, Do Jin Kim, Avi J Samelson

Science· November 2019

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Kinetic and structural comparison of a protein's cotranslational folding and refolding pathways.
Avi J Samelson, Eric Bolin, Shawn M Costello, Ajeet K Sharma, Edward P O'Brien

Sci Adv· May 2018

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Quantitative determination of ribosome nascent chain stability.
Avi J Samelson, Madeleine K Jensen, Randy A Soto, Jamie H D Cate, Susan Marqusee

Proc Natl Acad Sci U S A· November 2016

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HIV-1 Tat recruits transcription elongation factors dispersed along a flexible AFF4 scaffold.
Seemay Chou, Heather Upton, Katherine Bao, Ursula Schulze-Gahmen, Avi J Samelson

Proc Natl Acad Sci U S A· January 2013

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Accessing protein conformational ensembles using room-temperature X-ray crystallography.
James S Fraser, Henry van den Bedem, Avi J Samelson, P Therese Lang, James M Holton

Proc Natl Acad Sci U S A· September 2011

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