Publications by authors named "Bart Harper"

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Investigation of piperazine benzamides as human β adrenergic receptor agonists for the treatment of overactive bladder.
Bart H Harper, Liping Wang, Cheng Zhu, Nam F Kar, Bing Li

Bioorg Med Chem Lett· February 2017

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Discovery of Vibegron: A Potent and Selective β3 Adrenergic Receptor Agonist for the Treatment of Overactive Bladder.
Scott D Edmondson, Cheng Zhu, Nam Fung Kar, Jerry Di Salvo, Hiroshi Nagabukuro, Bart Harper

J Med Chem· January 2016

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Rapid development of two factor IXa inhibitors from hit to lead.
Dann L Parker, Shawn Walsh, Bing Li, Esther Kim, Aurash Sharipour, Bart Harper

Bioorg Med Chem Lett· June 2015

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Design, synthesis, and evaluation of conformationally restricted acetanilides as potent and selective β3 adrenergic receptor agonists for the treatment of overactive bladder.
Christopher R Moyes, Richard Berger, Stephen D Goble, Bart Harper, Dong-Ming Shen

J Med Chem· February 2014

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Heterocyclic acetamide and benzamide derivatives as potent and selective beta3-adrenergic receptor agonists with improved rodent pharmacokinetic profiles.
Stephen D Goble, Liping Wang, K Lulu Howell, Alka Bansal, Richard Berger, Bart Harper

Bioorg Med Chem Lett· March 2010

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2-Substituted piperazine-derived imidazole carboxamides as potent and selective CCK1R agonists for the treatment of obesity.
Richard Berger, Cheng Zhu, Alexa R Hansen, Bart Harper, Zhesheng Chen

Bioorg Med Chem Lett· September 2008

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Discovery of 3-aminopiperidines as potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitors.
Jason M Cox, Bart Harper, Anthony Mastracchio, Barbara Leiting, Ranabir Sinha Roy

Bioorg Med Chem Lett· August 2007

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(2S,3S)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-(4-[1,2,4]triazolo[1,5-a]-pyridin-6-ylphenyl)butanamide: a selective alpha-amino amide dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes.
Scott D Edmondson, Anthony Mastracchio, Robert J Mathvink, Jiafang He, Bart Harper

J Med Chem· June 2006

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