Publications by authors named "Benjamin A Thuma"

Claim this Profile
D
Discovery of High-Affinity Small-Molecule Binders of the Epigenetic Reader YEATS4.
Allyn T Londregan, Karlygash Aitmakhanova, James Bennett, Laura J Byrnes, Daniel P Canterbury, Benjamin A Thuma

J Med Chem· January 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
PF-07059013: A Noncovalent Modulator of Hemoglobin for Treatment of Sickle Cell Disease.
Ariamala Gopalsamy, Ann E Aulabaugh, Amey Barakat, Kevin C Beaumont, Shawn Cabral, Benjamin A Thuma

J Med Chem· January 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of PF-06835919: A Potent Inhibitor of Ketohexokinase (KHK) for the Treatment of Metabolic Disorders Driven by the Overconsumption of Fructose.
Kentaro Futatsugi, Aaron C Smith, Meihua Tu, Brian Raymer, Kay Ahn, Benjamin A Thuma

J Med Chem· November 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Optimizing the Benefit/Risk of Acetyl-CoA Carboxylase Inhibitors through Liver Targeting.
Kim Huard, Aaron C Smith, Gregg Cappon, Robert L Dow, David J Edmonds, Benjamin A Thuma

J Med Chem· October 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Small Molecule Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitors: Hit to Lead Optimization of Systemic Agents.
Allyn T Londregan, Liuqing Wei, Jun Xiao, Nathanael G Lintner, Donna Petersen, Benjamin A Thuma

J Med Chem· July 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Receptor-Mediated Delivery of CRISPR-Cas9 Endonuclease for Cell-Type-Specific Gene Editing.
Romain Rouet, Benjamin A Thuma, Marc D Roy, Nathanael G Lintner, David M Rubitski

J Am Chem Soc· May 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of a Novel Small-Molecule Modulator of C-X-C Chemokine Receptor Type 7 as a Treatment for Cardiac Fibrosis.
Elnaz Menhaji-Klotz, Kevin D Hesp, Allyn T Londregan, Amit S Kalgutkar, David W Piotrowski, Benjamin A Thuma

J Med Chem· April 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Optimization of Metabolic and Renal Clearance in a Series of Indole Acid Direct Activators of 5'-Adenosine Monophosphate-Activated Protein Kinase (AMPK).
David J Edmonds, Daniel W Kung, Amit S Kalgutkar, Kevin J Filipski, David C Ebner, Benjamin A Thuma

J Med Chem· March 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of Fragment-Derived Small Molecules for in Vivo Inhibition of Ketohexokinase (KHK).
Kim Huard, Kay Ahn, Paul Amor, David A Beebe, Kris A Borzilleri, Benjamin A Thuma

J Med Chem· September 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of a clinical candidate from the structurally unique dioxa-bicyclo[3.2.1]octane class of sodium-dependent glucose cotransporter 2 inhibitors.
Vincent Mascitti, Tristan S Maurer, Ralph P Robinson, Jianwei Bian, Carine M Boustany-Kari, Benjamin A Thuma

J Med Chem· April 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
2
2-[4-Chloro-3-(4-ethoxy-benz-yl)phen-yl]-1,3-dithiane.
Brian Samas, Cathy Préville, Benjamin A Thuma, Vincent Mascitti

Acta Crystallogr Sect E Struct Rep Online· May 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
C-Aryl glycoside inhibitors of SGLT2: Exploration of sugar modifications including C-5 spirocyclization.
Ralph P Robinson, Vincent Mascitti, Carine M Boustany-Kari, Christopher L Carr, Patrick M Foley, Benjamin A Thuma

Bioorg Med Chem Lett· March 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis