Publications by authors named "Benjamin Blasco"

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An all-in-one pipeline for the in vitro discovery and in vivo testing of Plasmodium falciparum malaria transmission blocking drugs.
Nicolas M B Brancucci, Christin Gumpp, Geert-Jan van Gemert, Xiao Yu, Armin Passecker, Benjamin Blasco

Nat Commun· July 2025

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susceptibilities to ganaplacide and diversity in potential resistance mediators in Ugandan isolates.
Oriana Kreutzfeld, Stephen Orena, Martin Okitwi, Patrick K Tumwebaze, Oswald Byaruhanga, Benjamin Blasco

Antimicrob Agents Chemother· September 2024

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Extending the Potency and Lifespan of Antibiotics: Inhibitors of Gram-Negative Bacterial Efflux Pumps.
Maëlle Duffey, Ravindra P Jumde, Renata M A da Costa, Henni-Karoliina Ropponen, Benjamin Blasco

ACS Infect Dis· May 2024

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High-throughput screening of small-molecules libraries identified antibacterials against clinically relevant multidrug-resistant A. baumannii and K. pneumoniae.
Benjamin Blasco, Soojin Jang, Hiroki Terauchi, Naoki Kobayashi, Shuichi Suzuki

EBioMedicine· April 2024

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Unrealized targets in the discovery of antibiotics for Gram-negative bacterial infections.
Ursula Theuretzbacher, Benjamin Blasco, Maëlle Duffey, Laura J V Piddock

Nat Rev Drug Discov· December 2023

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Susceptibility of Ugandan Plasmodium falciparum Isolates to the Antimalarial Drug Pipeline.
Oriana Kreutzfeld, Patrick K Tumwebaze, Martin Okitwi, Stephen Orena, Oswald Byaruhanga, Benjamin Blasco

Microbiol Spectr· June 2023

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Cation ATPase (ATP4) Orthologue Replacement in the Malaria Parasite Plasmodium knowlesi Reveals Species-Specific Responses to ATP4-Targeting Drugs.
Franziska Mohring, Donelly A van Schalkwyk, Ryan C Henrici, Benjamin Blasco, Didier Leroy

mBio· October 2022

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Assessing risks of Plasmodium falciparum resistance to select next-generation antimalarials.
Maëlle Duffey, Benjamin Blasco, Jeremy N Burrows, Timothy N C Wells, David A Fidock

Trends Parasitol· August 2021

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The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to parasite resistance.
James M Murithi, Cécile Pascal, Jade Bath, Xavier Boulenc, Nina F Gnädig, Benjamin Blasco

Sci Transl Med· July 2021

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Plasmodium knowlesi exhibits distinct in vitro drug susceptibility profiles from those of Plasmodium falciparum.
Donelly A van Schalkwyk, Benjamin Blasco, Rocio Davina Nuñez, Jonathan W K Liew, Amirah Amir

Int J Parasitol Drugs Drug Resist· April 2019

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Erratum for Brunschwig et al., "UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria".
Christel Brunschwig, Nina Lawrence, Dale Taylor, Efrem Abay, Mathew Njoroge, Benjamin Blasco

Antimicrob Agents Chemother· November 2018

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UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria.
Christel Brunschwig, Nina Lawrence, Dale Taylor, Efrem Abay, Mathew Njoroge, Benjamin Blasco

Antimicrob Agents Chemother· September 2018

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Comparison of the susceptibility of Plasmodium knowlesi and Plasmodium falciparum to antimalarial agents.
Donelly A van Schalkwyk, Robert W Moon, Benjamin Blasco, Colin J Sutherland

J Antimicrob Chemother· November 2017

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Antimalarial drug resistance: linking Plasmodium falciparum parasite biology to the clinic.
Benjamin Blasco, Didier Leroy, David A Fidock

Nat Med· August 2017

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Susceptibility Testing of Medically Important Parasites.
Abebe Genetu Bayih, Anjan Debnath, Edward Mitre, Christopher D Huston, Benoît Laleu, Benjamin Blasco

Clin Microbiol Rev· July 2017

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In vitro activity of anti-malarial ozonides against an artemisinin-resistant isolate.
Fabian Baumgärtner, Joëlle Jourdan, Christian Scheurer, Benjamin Blasco, Brice Campo

Malar J· January 2017

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A Triazolopyrimidine-Based Dihydroorotate Dehydrogenase Inhibitor with Improved Drug-like Properties for Treatment and Prevention of Malaria.
Margaret A Phillips, Karen L White, Sreekanth Kokkonda, Xiaoyi Deng, John White, Benjamin Blasco

ACS Infect Dis· December 2016

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Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
Wesley C Van Voorhis, John H Adams, Roberto Adelfio, Vida Ahyong, Myles H Akabas, Benjamin Blasco

PLoS Pathog· July 2016

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Functional dissection of intersubunit interactions in the EspR virulence regulator of Mycobacterium tuberculosis.
Benjamin Blasco, Aleksandre Japaridze, Marco Stenta, Basile I M Wicky, Giovanni Dietler

J Bacteriol· May 2014

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Virulence regulator EspR of Mycobacterium tuberculosis is a nucleoid-associated protein.
Benjamin Blasco, Jeffrey M Chen, Ruben Hartkoorn, Claudia Sala, Swapna Uplekar

PLoS Pathog· July 2012

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Atypical DNA recognition mechanism used by the EspR virulence regulator of Mycobacterium tuberculosis.
Benjamin Blasco, Marco Stenta, Livan Alonso-Sarduy, Giovanni Dietler, Matteo Dal Peraro

Mol Microbiol· October 2011

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