Publications by authors named "Benjamin G Bitler"

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SM08502-Mediated β-Catenin Repression Synergizes with Olaparib to Inhibit Tumor Progression.
Bradley R Corr, Elizabeth R Woodruff, Tomomi M Yamamoto, Kimberly R Jordan, Thomas Danhorn, Benjamin G Bitler

Cancer Res Commun· December 2025

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Mutant p53 binds and controls estrogen receptor activity to drive endocrine resistance in ovarian cancer.
Chunlei Shao, Alexandra Indeglia, Maya Foster, Kaitlyn Casey, Jessica Leung, Benjamin G Bitler

Genes Dev· November 2025

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Claudin-4 as a dual regulator of genome stability and immune evasion in high grade serous ovarian cancer.
Benjamin G Bitler, Julie Lang, Daniel Nunez-Avellaneda, Kian Behbakht, Natalie R Davidson

Sci Rep· November 2025

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A phase II, randomized, double-blind study of the use of rucaparib vs. placebo maintenance therapy in metastatic and recurrent endometrial cancer.
Bradley R Corr, Ashley Haggerty, Stefan M Gysler, Sarah Taylor, Kian Behbakht, Benjamin G Bitler

Gynecol Oncol· September 2025

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Utilizing Serum-Derived Lipidomics with Protein Biomarkers and Machine Learning for Early Detection of Ovarian Cancer in the Symptomatic Population.
Brendan M Giles, Rachel Culp-Hill, Robert A Law, Charles M Nichols, Mattie Goldberg, Benjamin G Bitler

Cancer Res Commun· September 2025

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Clinical Evaluation of a Multi-Omic Diagnostic Model for Early-Stage Ovarian Cancer Detection.
Robert A Law, Brendan M Giles, Rachel Culp-Hill, Enkhtuya Radnaa, Mattie Goldberg, Benjamin G Bitler

Diagnostics (Basel)· September 2025

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Targeting RAD52 overcomes PARP inhibitor resistance in preclinical -deficient ovarian cancer model.
Yukihide Ota, Vijayalaxmi Gupta, Bisiayo E Fashemi, Moreniola Akande, Preedia Babu, Benjamin G Bitler

bioRxiv· September 2025

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Multiple functions of PARP1 in the repair of DNA double strand breaks.
Raquel Ortega, Benjamin G Bitler, Nausica Arnoult

DNA Repair (Amst)· August 2025

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The chemotherapy-induced senescence-associated secretome promotes cell detachment and metastatic dissemination through metabolic reprogramming.
Aidan R Cole, Raquel Buj, Apoorva Uboveja, Evan Levasseur, Hui Wang, Benjamin G Bitler

bioRxiv· August 2025

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The evolving role of HER2 in gynecologic oncology and clinical trial design: A gynecologic pathologist's perspective.
Eseohi Ehimiaghe, Nicole Marjon, Miriam D Post, Bradley R Corr, Lindsay W Brubaker, Benjamin G Bitler

Gynecol Oncol· July 2025

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Ablation of hematopoietic stem cell derived adipocytes reduces tumor burden in syngeneic mouse models of high-grade serous carcinoma.
Elizabeth R Woodruff, Courtney A Bailey, Francis To, Vyshnavi Manda, Joanne K Maltzahn, Benjamin G Bitler

bioRxiv· June 2025

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Feasibility of assessing symptoms associated with ovarian cancer using an electronic medical intake questionnaire.
Eric D Helm, Cam Nguyen, Stephen Rotholz, Saketh R Guntupalli, Barbara A Goff, Benjamin G Bitler

Gynecol Oncol Rep· June 2025

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PARP1 and PARP2 are dispensable for DNA repair by microhomology-mediated end-joining during mitosis.
Raquel Ortega, Erin Taylor, Sophie M Whitehead, Thomas Danhorn, Benjamin G Bitler

bioRxiv· June 2025

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Leveraging Multi-omics to Disentangle the Complexity of Ovarian Cancer.
Shijuan Lin, Lily L Nguyen, Alexandra McMellen, Michael S Leibowitz, Natalie Davidson, Benjamin G Bitler

Mol Diagn Ther· March 2025

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Nuclear EGFR in breast cancer suppresses NK cell recruitment and cytotoxicity.
Angelica Escoto, Ryan Hecksel, Chance Parkinson, Sara Crane, Benjamin Atwell, Benjamin G Bitler

Oncogene· February 2025

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Claudin-4 Stabilizes the Genome via Nuclear and Cell-Cycle Remodeling to Support Ovarian Cancer Cell Survival.
Fabian R Villagomez, Julie Lang, Daniel Nunez-Avellaneda, Kian Behbakht, Hannah L Dimmick, Benjamin G Bitler

Cancer Res Commun· January 2025

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EHMT1/2 Inhibition Promotes Regression of Therapy-Resistant Ovarian Cancer Tumors in a CD8 T-cell-Dependent Manner.
Lily L Nguyen, Zachary L Watson, Raquel Ortega, Elizabeth R Woodruff, Kimberly R Jordan, Benjamin G Bitler

Mol Cancer Res· December 2024

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Regulation of human interferon signaling by transposon exonization.
Giulia Irene Maria Pasquesi, Holly Allen, Atma Ivancevic, Arturo Barbachano-Guerrero, Olivia Joyner, Benjamin G Bitler

Cell· December 2024

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Cannabidiol promotes apoptosis and downregulation of oncogenic factors.
Ashley Greenwood, Tomomi M Yamamoto, Molishree Joshi, Kent Hutchison, Benjamin G Bitler

bioRxiv· December 2024

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The Spatial Structure of the Tumor Immune Microenvironment Can Explain and Predict Patient Response in High-Grade Serous Carcinoma.
Lucy B Van Kleunen, Mansooreh Ahmadian, Miriam D Post, Rebecca J Wolsky, Christian Rickert, Benjamin G Bitler

Cancer Immunol Res· November 2024

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Polycomb Repressor Complex 1 (PRC1) in ovarian cancer: A scoping literature review.
Jessica Floyd, Kristen DeSanto, Benjamin G Bitler, Lindsay W Brubaker

Crit Rev Oncol Hematol· October 2024

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Blocking Tryptophan Catabolism Reduces Triple-Negative Breast Cancer Invasive Capacity.
Li-Wei Kuo, Lyndsey S Crump, Kathleen O'Neill, Michelle M Williams, Jessica L Christenson, Benjamin G Bitler

Cancer Res Commun· October 2024

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Claudin-4 remodeling of nucleus-cell cycle crosstalk maintains ovarian tumor genome stability and drives resistance to genomic instability-inducing agents.
Fabian R Villagomez, Julie Lang, Daniel Nunez-Avellaneda, Kian Behbakht, Hannah L Dimmick, Benjamin G Bitler

bioRxiv· September 2024

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Tumor-Intrinsic Activity of Chromobox 2 Remodels the Tumor Microenvironment in High-grade Serous Carcinoma.
Ritsuko Iwanaga, Tomomi M Yamamoto, Karina Gomez, Lily L Nguyen, Elizabeth R Woodruff, Benjamin G Bitler

Cancer Res Commun· August 2024

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Claudin-4 Modulates Autophagy via SLC1A5/LAT1 as a Mechanism to Regulate Micronuclei.
Fabian R Villagomez, Julie Lang, Fredrick J Rosario, Daniel Nunez-Avellaneda, Patricia Webb, Benjamin G Bitler

Cancer Res Commun· July 2024

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