Publications by authors named "Benoit Devogelaere"

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Multi-centre evaluation of a comprehensive preimplantation genetic test through haplotyping-by-sequencing.
Heleen Masset, Masoud Zamani Esteki, Eftychia Dimitriadou, Jos Dreesen, Sophie Debrock, Benoit Devogelaere

Hum Reprod· August 2019

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Characterization of a dengue NS4B inhibitor originating from an HCV small molecule library.
Ilane Hernandez-Morales, Peggy Geluykens, Marleen Clynhens, Rudy Strijbos, Olivia Goethals, Benoit Devogelaere

Antiviral Res· November 2017

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BRAF Mutation Testing in Cell-Free DNA from the Plasma of Patients with Advanced Cancers Using a Rapid, Automated Molecular Diagnostics System.
Filip Janku, Helen J Huang, Bart Claes, Gerald S Falchook, Siqing Fu, Benoit Devogelaere

Mol Cancer Ther· June 2016

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BRAF mutation testing with a rapid, fully integrated molecular diagnostics system.
Filip Janku, Bart Claes, Helen J Huang, Gerald S Falchook, Benoit Devogelaere

Oncotarget· September 2015

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Discovery and early development of TMC647055, a non-nucleoside inhibitor of the hepatitis C virus NS5B polymerase.
Maxwell D Cummings, Tse-I Lin, Lili Hu, Abdellah Tahri, David McGowan, Benoit Devogelaere

J Med Chem· March 2014

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Surface plasmon resonance as a tool to select potent drug candidates for hepatitis C virus NS5B polymerase.
Erna Cleiren, Benoit Devogelaere, Katleen Fierens

Methods Mol Biol· January 2014

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Expression and purification of dengue virus NS5 polymerase and development of a high-throughput enzymatic assay for screening inhibitors of dengue polymerase.
Edwin Yunhao Gong, Hannah Kenens, Tania Ivens, Koen Dockx, Katrien Vermeiren, Benoit Devogelaere

Methods Mol Biol· January 2014

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TMC647055, a potent nonnucleoside hepatitis C virus NS5B polymerase inhibitor with cross-genotypic coverage.
Benoit Devogelaere, Jan Martin Berke, Leen Vijgen, Pascale Dehertogh, Els Fransen

Antimicrob Agents Chemother· September 2012

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Finger loop inhibitors of the HCV NS5b polymerase. Part II. Optimization of tetracyclic indole-based macrocycle leading to the discovery of TMC647055.
Sandrine Vendeville, Tse-I Lin, Lili Hu, Abdellah Tahri, David McGowan, Benoit Devogelaere

Bioorg Med Chem Lett· July 2012

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Structure-based macrocyclization yields hepatitis C virus NS5B inhibitors with improved binding affinities and pharmacokinetic properties.
Maxwell D Cummings, Tse-I Lin, Lili Hu, Abdellah Tahri, David McGowan, Benoit Devogelaere

Angew Chem Int Ed Engl· May 2012

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Unraveling the role of polycystin-2/inositol 1,4,5-trisphosphate receptor interaction in Ca signaling.
Eva Sammels, Benoit Devogelaere, Djalila Mekahli, Geert Bultynck, Ludwig Missiaen

Commun Integr Biol· November 2010

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Polycystin-2 activation by inositol 1,4,5-trisphosphate-induced Ca2+ release requires its direct association with the inositol 1,4,5-trisphosphate receptor in a signaling microdomain.
Eva Sammels, Benoit Devogelaere, Djalila Mekahli, Geert Bultynck, Ludwig Missiaen

J Biol Chem· June 2010

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1a/1b subtype profiling of nonnucleoside polymerase inhibitors of hepatitis C virus.
Origène Nyanguile, Benoit Devogelaere, Leen Vijgen, Walter Van den Broeck, Frederik Pauwels

J Virol· March 2010

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Structure-based design of a benzodiazepine scaffold yields a potent allosteric inhibitor of hepatitis C NS5B RNA polymerase.
Koen Vandyck, Maxwell D Cummings, Origène Nyanguile, Carlo W Boutton, Sandrine Vendeville, Benoit Devogelaere

J Med Chem· July 2009

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Regulation of inositol 1,4,5-trisphosphate-induced Ca2+ release by reversible phosphorylation and dephosphorylation.
Veerle Vanderheyden, Benoit Devogelaere, Ludwig Missiaen, Humbert De Smedt, Geert Bultynck

Biochim Biophys Acta· June 2009

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Heterogeneous nuclear ribonucleoprotein h1, a novel nuclear autoantigen.
Karolien Van den Bergh, Herbert Hooijkaas, Daniel Blockmans, René Westhovens, Katrijn Op De Beéck, Benoit Devogelaere

Clin Chem· May 2009

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The IRBIT domain adds new functions to the AHCY family.
Benoit Devogelaere, Eva Sammels, Humbert De Smedt

Bioessays· July 2008

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The complex regulatory function of the ligand-binding domain of the inositol 1,4,5-trisphosphate receptor.
Benoit Devogelaere, Leen Verbert, Jan B Parys, Ludwig Missiaen, Humbert De Smedt

Cell Calcium· January 2008

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Protein phosphatase-1 is a novel regulator of the interaction between IRBIT and the inositol 1,4,5-trisphosphate receptor.
Benoit Devogelaere, Monique Beullens, Eva Sammels, Rita Derua, Etienne Waelkens

Biochem J· October 2007

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Molecular and functional characterization of inositol trisphosphate receptors during early zebrafish development.
Rachel Ashworth, Benoit Devogelaere, Jez Fabes, Richard E Tunwell, Kevin R Koh

J Biol Chem· May 2007

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Binding of IRBIT to the IP3 receptor: determinants and functional effects.
Benoit Devogelaere, Nael Nadif Kasri, Rita Derua, Etienne Waelkens, Geert Callewaert

Biochem Biophys Res Commun· April 2006

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