Publications by authors named "Benoit Giasson"

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Basic Science and Pathogenesis.
Zachary Strickland, Benoit Giasson, Jada Lewis

Alzheimers Dement· December 2025

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Uncovering α-synuclein and tau burden in Alzheimer's and Lewy body diseases.
Stephan Quintin, Giavanna Paterno, Grace M Lloyd, Stefan Prokop, Benoit I Giasson

Brain Commun· October 2025

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Progressive Supranuclear Palsy PERK haplotype B selectively translates DLX1 promoting tau toxicity.
Christian B Lessard, Diego Rubio-Rubio, Samantha Tolton, Marangelie Criado-Marrero, Sakthivel Ravi, Benoit I Giasson

bioRxiv· July 2025

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A novel pThr217 tau monoclonal antibody reveals neuropathological heterogeneity in tauopathies.
Giavanna Paterno, Brach M Bell, Kimberly-Marie M Gorion, Stephan Quintin, Stefan Prokop, Benoit I Giasson

Sci Rep· June 2025

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Tau from SPAM Transgenic Mice Exhibit Potent Strain-Specific Prion-Like Seeding Properties Characteristic of Human Neurodegenerative Diseases.
Ethan D Smith, Giavanna Paterno, Brach M Bell, Kimberly-Marie M Gorion, Stefan Prokop, Benoit I Giasson

Neuromolecular Med· May 2025

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Neuronal tissue collection from intra-cranial instruments used in deep brain stimulation surgery for Parkinson's disease with implications for study of alpha-synuclein.
Zachary A Sorrentino, Joshua Riklan, Grace M Lloyd, Brandon P Lucke-Wold, David Mampre, Benoit I Giasson

Sci Rep· September 2024

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Novel Monoclonal Antibody Specific toward Amyloid-β Binds to a Unique Epitope within the N-Terminal Region.
Giavanna Paterno, Brenda D Moore, Brach M Bell, Kimberly-Marie M Gorion, Yong Ran, Benoit I Giasson

Antibodies (Basel)· August 2024

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A multiverse of α-synuclein: investigation of prion strain properties with carboxyl-terminal truncation specific antibodies in animal models.
Grace M Lloyd, Stephan Quintin, Zachary A Sorrentino, Kimberly-Marie M Gorion, Brach M Bell, Benoit I Giasson

Acta Neuropathol Commun· June 2024

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Analysis of alpha-synuclein harvested from intracranial instruments used in deep brain stimulation surgery for Parkinson's disease.
Zachary Sorrentino, Joshua Riklan, Grace Lloyd, Brandon Lucke-Wold, David Mampre, Benoit Giasson

Res Sq· May 2024

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Correction: Collusion of α-Synuclein and Aβ aggravating co-morbidities in a novel prion-type mouse model.
Grace M Lloyd, Jess-Karan S Dhillon, Kimberly-Marie M Gorion, Cara Riffe, Susan E Fromholt, Benoit I Giasson

Mol Neurodegener· February 2024

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A C1qTNF3 collagen domain fusion chaperones diverse secreted proteins and anti-Aβ scFvs: Applications for gene therapies.
Brenda D Moore, Yong Ran, Marshall S Goodwin, Kavitha Komatineni, Karen N McFarland, Benoit I Giasson

Mol Ther Methods Clin Dev· December 2023

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Polymerization of recombinant tau core fragments and seeding studies in cultured cells.
Giavanna Paterno, Brach M Bell, Alexis Riley-DiPaolo, Matthew J LaVoie, Benoit I Giasson

Front Neurosci· December 2023

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Human tauopathy strains defined by phosphorylation in R1-R2 repeat domains of tau.
Ethan D Smith, Quan Vo, Benoit I Giasson, David R Borchelt, Stefan Prokop

Acta Neuropathol Commun· October 2023

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Differentiating pathologic tau in chronic traumatic encephalopathy (CTE) from other tauopathies: A potential antibody panel assessment.
Zachary A Sorrentino, Giavanna Paterno, Benoit I Giasson, Julian E Bailes, John M Lee

J Neuropathol Exp Neurol· September 2023

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Novel Conformation-Dependent Tau Antibodies Are Modulated by Adjacent Phosphorylation Sites.
Giavanna Paterno, Jose Torrellas, Brach M Bell, Kimberly-Marie M Gorion, Stephan S Quintin, Benoit I Giasson

Int J Mol Sci· September 2023

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Cellular processing of α-synuclein fibrils results in distinct physiological C-terminal truncations with a major cleavage site at residue Glu 114.
Stephan Quintin, Grace M Lloyd, Giavanna Paterno, Yuxing Xia, Zachary Sorrentino, Benoit I Giasson

J Biol Chem· July 2023

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Carboxyl truncation of α-synuclein occurs early and is influenced by human APOE genotype in transgenic mouse models of α-synuclein pathogenesis.
Grace M Lloyd, Brooke Long, Stephan Quintin, Zachary A Sorrentino, Kimberly-Marie M Gorion, Benoit I Giasson

Acta Neuropathol Commun· July 2023

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Tau Lysine Pseudomethylation Regulates Microtubule Binding and Enhances Prion-like Tau Aggregation.
Yuxing Xia, Brach M Bell, Benoit I Giasson

Int J Mol Sci· May 2023

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Tau mutation S356T in the three repeat isoform leads to microtubule dysfunction and promotes prion-like seeded aggregation.
Yuxing Xia, Brach M Bell, Justin D Kim, Benoit I Giasson

Front Neurosci· May 2023

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Evaluation of an Adoptive Cellular Therapy-Based Vaccine in a Transgenic Mouse Model of α-synucleinopathy.
Winston T Chu, Jesse Hall, Anjela Gurrala, Alexander Becsey, Shreya Raman, Benoit I Giasson

ACS Chem Neurosci· January 2023

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Optical pulse labeling studies reveal exogenous seeding slows α-synuclein clearance.
Cara L Croft, Giavanna Paterno, Ava R Vause, Lyla A Rowe, Daniel H Ryu, Benoit I Giasson

NPJ Parkinsons Dis· December 2022

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Corrigendum to "Carboxy-terminal truncation and phosphorylation of α-synuclein elongates survival in a prion-like seeding mouse model of synucleinopathy" [Neurosci. Lett. 732 (2020) 1-11/135017].
Zachary A Sorrentino, Ethan Hass, Niran Vijayaraghavan, Kimberly-Marie Gorion, Cara J Riffe, Benoit I Giasson

Neurosci Lett· July 2022

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Regulates Transmission of α-Synuclein-Seeded Pathology in Mice.
Elsa Gonzalez De La Cruz, Quan Vo, Katie Moon, Karen N McFarland, Mary Weinrich, Benoit I Giasson

Int J Mol Sci· July 2022

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Reassessment of Neuronal Tau Distribution in Adult Human Brain and Implications for Tau Pathobiology.
Giavanna Paterno, Brach M Bell, Kimberly-Marie M Gorion, Stefan Prokop, Benoit I Giasson

Acta Neuropathol Commun· June 2022

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Pathogenic tau recruits wild-type tau into brain inclusions and induces gut degeneration in transgenic SPAM mice.
Yuxing Xia, Stefan Prokop, Brach M Bell, Kimberly-Marie M Gorion, Cara L Croft, Benoit I Giasson

Commun Biol· May 2022

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