Publications by authors named "Birgit Rasenberger"

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Therapy-induced senescence of glioblastoma cells is determined by the p21-CDK1/2 axis and does not require activation of DREAM.
Christian Schwarzenbach, Justus Rinke, Juliana B Vilar, Jason Sallbach, Larissa Tatsch, Birgit Rasenberger

Cell Death Dis· May 2025

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The cell cycle inhibitor p21 is essential for irinotecan-induced senescence and plays a decisive role in re-sensitization of temozolomide-resistant glioblastoma cells to irinotecan.
Jason Sallbach, Melanie Woods, Birgit Rasenberger, Markus Christmann, Maja T Tomicic

Biomed Pharmacother· December 2024

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The p21CIP1-CDK4-DREAM axis is a master regulator of genotoxic stress-induced cellular senescence.
Ariane Schmidt, Sebastian Allmann, Christian Schwarzenbach, Petra Snyder, Jia-Xuan Chen, Birgit Rasenberger

Nucleic Acids Res· July 2024

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p53 triggers mitochondrial apoptosis following DNA damage-dependent replication stress by the hepatotoxin methyleugenol.
Max J Carlsson, Anastasia S Vollmer, Philipp Demuth, Daniel Heylmann, Diana Reich, Birgit Rasenberger

Cell Death Dis· November 2022

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The Mitochondrial Disruptor Devimistat (CPI-613) Synergizes with Genotoxic Anticancer Drugs in Colorectal Cancer Therapy in a Bim-Dependent Manner.
Carina Arnold, Philipp Demuth, Nina Seiwert, Simon Wittmann, Kerstin Boengler, Birgit Rasenberger

Mol Cancer Ther· January 2022

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Targeting c-IAP1, c-IAP2, and Bcl-2 Eliminates Senescent Glioblastoma Cells Following Temozolomide Treatment.
Christian Schwarzenbach, Larissa Tatsch, Juliana Brandstetter Vilar, Birgit Rasenberger, Lea Beltzig

Cancers (Basel)· July 2021

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Natural Merosesquiterpenes Activate the DNA Damage Response via DNA Strand Break Formation and Trigger Apoptotic Cell Death in p53-Wild-type and Mutant Colorectal Cancer.
Apisada Jiso, Philipp Demuth, Madeleine Bachowsky, Manuel Haas, Nina Seiwert, Birgit Rasenberger

Cancers (Basel)· June 2021

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Functional mismatch repair and inactive p53 drive sensitization of colorectal cancer cells to irinotecan via the IAP antagonist BV6.
Maja T Tomicic, Christian Steigerwald, Birgit Rasenberger, Anamaria Brozovic, Markus Christmann

Arch Toxicol· August 2019

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Lipoic Acid Synergizes with Antineoplastic Drugs in Colorectal Cancer by Targeting p53 for Proteasomal Degradation.
Carina Neitzel, Nina Seiwert, Anja Göder, Erika Diehl, Carina Weber, Birgit Rasenberger

Cells· July 2019

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Sensitization of colorectal cancer cells to irinotecan by the Survivin inhibitor LLP3 depends on XAF1 proficiency in the context of mutated p53.
Christian Steigerwald, Birgit Rasenberger, Markus Christmann, Maja T Tomicic

Arch Toxicol· August 2018

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Delayed c-Fos activation in human cells triggers XPF induction and an adaptive response to UVC-induced DNA damage and cytotoxicity.
Maja T Tomicic, Patricia Reischmann, Birgit Rasenberger, Ruth Meise, Bernd Kaina

Cell Mol Life Sci· May 2011

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