Publications by authors named "Bruce Surber"

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Synthesis of [H-3]- and [C-14]-labeled elagolix.
Eric D Soli, Bruce W Surber, Aimee D Reed

J Labelled Comp Radiopharm· June 2021

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Metabolism and Disposition of Pan-Genotypic Inhibitor of Hepatitis C Virus NS5A Ombitasvir in Humans.
Jianwei Shen, Michael Serby, Bruce Surber, Anthony J Lee, Junli Ma

Drug Metab Dispos· August 2016

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A (14)C-leucine absorption, distribution, metabolism and excretion (ADME) study in adult Sprague-Dawley rat reveals β-hydroxy-β-methylbutyrate as a metabolite.
Anthony J Lee, David W A Beno, Xiaolin Zhang, Robin Shapiro, Mark Mason, Bruce Surber

Amino Acids· May 2015

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Iniparib nonselectively modifies cysteine-containing proteins in tumor cells and is not a bona fide PARP inhibitor.
Xuesong Liu, Yan Shi, David X Maag, Joann P Palma, Melanie J Patterson, Bruce W Surber

Clin Cancer Res· January 2012

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[3H]A-804598 ([3H]2-cyano-1-[(1S)-1-phenylethyl]-3-quinolin-5-ylguanidine) is a novel, potent, and selective antagonist radioligand for P2X7 receptors.
Diana L Donnelly-Roberts, Marian T Namovic, Bruce Surber, Srirajan X Vaidyanathan, Arturo Perez-Medrano

Neuropharmacology· January 2009

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Pharmacological MRI in awake rats predicts selective binding of alpha4beta2 nicotinic receptors.
Chih-Liang Chin, James R Pauly, Bruce W Surber, Pamela D Skoubis, Steve McGaraughty

Synapse· March 2008

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[3H]A-585539 [(1S,4S)-2,2-dimethyl-5-(6-phenylpyridazin-3-yl)-5-aza-2-azoniabicyclo[2.2.1]heptane], a novel high-affinity alpha7 neuronal nicotinic receptor agonist: radioligand binding characterization to rat and human brain.
David J Anderson, William Bunnelle, Bruce Surber, Jia Du, Carol Surowy

J Pharmacol Exp Ther· January 2008

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[3H]A-778317 [1-((R)-5-tert-butyl-indan-1-yl)-3-isoquinolin-5-yl-urea]: a novel, stereoselective, high-affinity antagonist is a useful radioligand for the human transient receptor potential vanilloid-1 (TRPV1) receptor.
Bruce R Bianchi, Rachid El Kouhen, Torben R Neelands, Chih-Hung Lee, Arthur Gomtsyan, Bruce Surber

J Pharmacol Exp Ther· October 2007

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Detection of multiple H3 receptor affinity states utilizing [3H]A-349821, a novel, selective, non-imidazole histamine H3 receptor inverse agonist radioligand.
David G Witte, Betty Bei Yao, Thomas R Miller, Tracy L Carr, Steven Cassar, Bruce W Surber

Br J Pharmacol· July 2006

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Thrombospondin-1 mimetic peptide inhibitors of angiogenesis and tumor growth: design, synthesis, and optimization of pharmacokinetics and biological activities.
Fortuna Haviv, Michael F Bradley, Douglas M Kalvin, Andrew J Schneider, Donald J Davidson, Bruce W Surber

J Med Chem· April 2005

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Synthesis and activity of 2-[4-(4-[3H]-2-cyanophenyl)piperazinyl]-N-(2,4,6-[3H]3-3-methylphenyl)acetamide: a selective dopamine D4 receptor agonist and radioligand.
Mark A Matulenko, Bruce Surber, Leimin Fan, Teodozyi Kolasa, Masaki Nakane

Bioorg Med Chem Lett· October 2004

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[3H] A-369508 ([2-[4-(2-cyanophenyl)-1-piperazinyl]-N-(3-methylphenyl) acetamide): an agonist radioligand selective for the dopamine D4 receptor.
Robert B Moreland, Marc A Terranova, Renjie Chang, Marie E Uchic, Mark A Matulenko, Bruce W Surber

Eur J Pharmacol· August 2004

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