Publications by authors named "Steven Cassar"

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Optimization of Zebrafish Larvae Sectioning for Mass Spectrometry Imaging.
Junhai Yang, Lauren Rendino, Steven Cassar, Wayne Buck, James Sawicki

Pharmaceuticals (Basel)· October 2022

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Zebrafish as an Animal Model for Ocular Toxicity Testing: A Review of Ocular Anatomy and Functional Assays.
Steven Cassar, Christina Dunn, Meg Ferrell Ramos

Toxicol Pathol· April 2021

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Use of Zebrafish in Drug Discovery Toxicology.
Steven Cassar, Isaac Adatto, Jennifer L Freeman, Joshua T Gamse, Iñaki Iturria

Chem Res Toxicol· January 2020

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A multi-institutional study benchmarking the zebrafish developmental assay for prediction of embryotoxic plasma concentrations from rat embryo-fetal development studies.
Steven Cassar, Manon Beekhuijzen, Bruce Beyer, Robert Chapin, Martina Dorau

Reprod Toxicol· June 2019

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High-throughput Measurement of Gut Transit Time Using Larval Zebrafish.
Steven Cassar, Xin Huang, Todd Cole

J Vis Exp· October 2018

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Design of Aminobenzothiazole Inhibitors of Rho Kinases 1 and 2 by Using Protein Kinase A as a Structure Surrogate.
Russell A Judge, Anil Vasudevan, Victoria E Scott, Gricelda H Simler, Steve D Pratt, Steven C Cassar

Chembiochem· March 2018

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From the Cover: Inhibitors of Nicotinamide Phosphoribosyltransferase Cause Retinal Damage in Larval Zebrafish.
Steven Cassar, Christina Dunn, Amanda Olson, Wayne Buck, Stacey Fossey

Toxicol Sci· February 2018

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Measuring drug absorption improves interpretation of behavioral responses in a larval zebrafish locomotor assay for predicting seizure liability.
Steven Cassar, Laura Breidenbach, Amanda Olson, Xin Huang, Heather Britton

J Pharmacol Toxicol Methods· November 2017

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A high-throughput method for predicting drug effects on gut transit time using larval zebrafish.
Steven Cassar, Xin Huang, Todd Cole

J Pharmacol Toxicol Methods· September 2016

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Pharmacological modulation of brain activity in a preclinical model of osteoarthritis.
Jaymin Upadhyay, Scott J Baker, Rajasimhan Rajagovindan, Michelle Hart, Prasant Chandran, Steven Cassar

Neuroimage· January 2013

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Importance of M2-M3 loop in governing properties of genistein at the α7 nicotinic acetylcholine receptor inferred from α7/5-HT3A chimera.
Jens Halvard Grønlien, Hilde Ween, Kirsten Thorin-Hagene, Steven Cassar, Jinhe Li

Eur J Pharmacol· November 2010

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Comparing levels of biochemical markers in CSF from cannulated and non-cannulated rats.
Steven C Cassar, Ann E Tovcimak, Nathan R Rustay, Teresa A Ellis, Bradley A Hooker

J Neurosci Methods· October 2010

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Positive allosteric modulation of the alpha7 nicotinic acetylcholine receptor: ligand interactions with distinct binding sites and evidence for a prominent role of the M2-M3 segment.
Daniel Bertrand, Sonia Bertrand, Steven Cassar, Earl Gubbins, Jinhe Li

Mol Pharmacol· November 2008

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Molecular determinants of species-specific activation or blockade of TRPA1 channels.
Jun Chen, Xu-Feng Zhang, Michael E Kort, Jeffrey R Huth, Chaohong Sun, Steven C Cassar

J Neurosci· May 2008

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Utility of large-scale transiently transfected cells for cell-based high-throughput screens to identify transient receptor potential channel A1 (TRPA1) antagonists.
Jun Chen, Marc R Lake, Reza S Sabet, Wende Niforatos, Steve D Pratt, Steven C Cassar

J Biomol Screen· February 2007

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Association of Catsper1 or -2 with Ca(v)3.3 leads to suppression of T-type calcium channel activity.
Di Zhang, Jun Chen, Anita Saraf, Steven Cassar, Ping Han

J Biol Chem· August 2006

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Detection of multiple H3 receptor affinity states utilizing [3H]A-349821, a novel, selective, non-imidazole histamine H3 receptor inverse agonist radioligand.
David G Witte, Betty Bei Yao, Thomas R Miller, Tracy L Carr, Steven Cassar

Br J Pharmacol· July 2006

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A novel potassium channel encoded by Ectocarpus siliculosus virus.
Jun Chen, Steven C Cassar, Di Zhang, Murali Gopalakrishnan

Biochem Biophys Res Commun· January 2005

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Species comparison and pharmacological characterization of rat and human CB2 cannabinoid receptors.
Sutapa Mukherjee, Monique Adams, Kristi Whiteaker, Anthony Daza, Karen Kage, Steven Cassar

Eur J Pharmacol· November 2004

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Tissue specific expression of alternative splice forms of human cyclic nucleotide gated channel subunit CNGA3.
Steven C Cassar, Jun Chen, Di Zhang, Murali Gopalakrishnan

Mol Vis· October 2004

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CYP3A5 genotype has a dose-dependent effect on ABT-773 plasma levels.
David A Katz, David R Grimm, Steven C Cassar, Maria C Gentile, Xin Ye

Clin Pharmacol Ther· June 2004

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Cloning and pharmacological characterization of the monkey histamine H3 receptor.
Betty Bei Yao, Rahul Sharma, Steven Cassar, Timothy A Esbenshade, Arthur A Hancock

Eur J Pharmacol· December 2003

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Use of a fluorescent imaging plate reader--based calcium assay to assess pharmacological differences between the human and rat vanilloid receptor.
David G Witte, Steven C Cassar, Jeffrey N Masters, Timothy Esbenshade, Arthur A Hancock

J Biomol Screen· October 2002

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