Publications by authors named "Timothy A Esbenshade"

Claim this Profile
Î
α7 Nicotinic receptor agonist enhances cognition in aged 3xTg-AD mice with robust plaques and tangles.
Rodrigo Medeiros, Nicholas A Castello, David Cheng, Masashi Kitazawa, David Baglietto-Vargas, Timothy A Esbenshade

Am J Pathol· February 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Assessment of the abuse liability of ABT-288, a novel histamine H₃ receptor antagonist.
Thomas J Hudzik, Ana Basso, Janel M Boyce-Rustay, William Bracken, Kaitlin E Browman, Timothy A Esbenshade

Psychopharmacology (Berl)· July 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Pharmacological properties and procognitive effects of ABT-288, a potent and selective histamine H3 receptor antagonist.
Timothy A Esbenshade, Kaitlin E Browman, Thomas R Miller, Kathleen M Krueger, Victoria Komater-Roderwald

J Pharmacol Exp Ther· October 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Antinociceptive effects of histamine H3 receptor antagonist in the preclinical models of pain in rats and the involvement of central noradrenergic systems.
Gin C Hsieh, Prisca Honore, Madhavi Pai, Erica J Wensink, Prasant Chandran, Timothy A Esbenshade

Brain Res· October 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
In vitro studies on a class of quinoline containing histamine H3 antagonists.
Huaqing Liu, Robert J Altenbach, Gilbert J Diaz, Arlene M Manelli, Ruth L Martin, Timothy A Esbenshade

Bioorg Med Chem Lett· June 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
H4 receptor antagonism exhibits anti-nociceptive effects in inflammatory and neuropathic pain models in rats.
Gin C Hsieh, Prasant Chandran, Anita K Salyers, Madhavi Pai, Chang Z Zhu, Timothy A Esbenshade

Pharmacol Biochem Behav· March 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Rigidified 2-aminopyrimidines as histamine H4 receptor antagonists: effects of substitution about the rigidifying ring.
John R Koenig, Huaqing Liu, Irene Drizin, David G Witte, Tracy L Carr, Timothy A Esbenshade

Bioorg Med Chem Lett· March 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Design of a new histamine H3 receptor antagonist chemotype: (3aR,6aR)-5-alkyl-1-aryl-octahydropyrrolo[3,4-b]pyrroles, synthesis, and structure-activity relationships.
Chen Zhao, Minghua Sun, Youssef L Bennani, Thomas R Miller, David G Witte, Timothy A Esbenshade

J Med Chem· August 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Localization of histamine H4 receptors in the central nervous system of human and rat.
Marina I Strakhova, Arthur L Nikkel, Arlene M Manelli, Gin C Hsieh, Timothy A Esbenshade

Brain Res· January 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Cloning and characterization of the monkey histamine H3 receptor isoforms.
Marina I Strakhova, Gerard B Fox, Tracy L Carr, David G Witte, Timothy A Vortherms, Timothy A Esbenshade

Eur J Pharmacol· December 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.
Huaqing Liu, Robert J Altenbach, Tracy L Carr, Prasant Chandran, Gin C Hsieh, Timothy A Esbenshade

J Med Chem· November 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure-activity studies on a series of a 2-aminopyrimidine-containing histamine H4 receptor ligands.
Robert J Altenbach, Ronald M Adair, Brian M Bettencourt, Lawrence A Black, Shannon R Fix-Stenzel, Timothy A Esbenshade

J Med Chem· October 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Rotationally constrained 2,4-diamino-5,6-disubstituted pyrimidines: a new class of histamine H4 receptor antagonists with improved druglikeness and in vivo efficacy in pain and inflammation models.
Marlon D Cowart, Robert J Altenbach, Huaqing Liu, Gin C Hsieh, Irene Drizin, Timothy A Esbenshade

J Med Chem· October 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The alkaloid conessine and analogues as potent histamine H3 receptor antagonists.
Chen Zhao, Minghua Sun, Youssef L Bennani, Sujatha M Gopalakrishnan, David G Witte, Timothy A Esbenshade

J Med Chem· September 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A robust and high-capacity [(35)S]GTPgammaS binding assay for determining antagonist and inverse agonist pharmacological parameters of histamine H(3) receptor ligands.
Thomas R Miller, John L Baranowski, Brian R Estvander, David G Witte, Tracy L Carr, Timothy A Esbenshade

Assay Drug Dev Technol· June 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
In vitro SAR of pyrrolidine-containing histamine H3 receptor antagonists: trends across multiple chemical series.
Diana L Nersesian, Lawrence A Black, Thomas R Miller, Timothy A Vortherms, Timothy A Esbenshade

Bioorg Med Chem Lett· January 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
An 80-amino acid deletion in the third intracellular loop of a naturally occurring human histamine H3 isoform confers pharmacological differences and constitutive activity.
Gerold Bongers, Kathleen M Krueger, Thomas R Miller, John L Baranowski, Brian R Estvander, Timothy A Esbenshade

J Pharmacol Exp Ther· December 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis, potency, and in vivo profiles of quinoline containing histamine H3 receptor inverse agonists.
Robert J Altenbach, Huaqing Liu, Patricia N Banfor, Kaitlin E Browman, Gerard B Fox, Timothy A Esbenshade

J Med Chem· November 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Novel heterocyclic-substituted benzofuran histamine H3 receptor antagonists: in vitro properties, drug-likeness, and behavioral activity.
Marlon Cowart, Gregory A Gfesser, Kaitlin E Browman, Ramin Faghih, Thomas R Miller, Timothy A Esbenshade

Biochem Pharmacol· April 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
4
4-[6-(2-Aminoethyl)naphthalen-2-yl]benzonitriles are potent histamine H3 receptor antagonists with high CNS penetration.
Lawrence A Black, Diana L Nersesian, Padam Sharma, Yi-Yin Ku, Youssef L Bennani, Timothy A Esbenshade

Bioorg Med Chem Lett· March 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Evidence for tolerance following repeated dosing in rats with ciproxifan, but not with A-304121.
Jia Bao Pan, Betty B Yao, Thomas R Miller, Paul E Kroeger, Youssef L Bennani, Timothy A Esbenshade

Life Sci· August 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Detection of multiple H3 receptor affinity states utilizing [3H]A-349821, a novel, selective, non-imidazole histamine H3 receptor inverse agonist radioligand.
David G Witte, Betty Bei Yao, Thomas R Miller, Tracy L Carr, Steven Cassar, Timothy A Esbenshade

Br J Pharmacol· July 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Lack of efficacy of melanin-concentrating hormone-1 receptor antagonists in models of depression and anxiety.
Ana M Basso, Natalie A Bratcher, Kelly B Gallagher, Marlon D Cowart, Chen Zhao, Timothy A Esbenshade

Eur J Pharmacol· July 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Histamine H3 receptor antagonists: preclinical promise for treating obesity and cognitive disorders.
Timothy A Esbenshade, Gerard B Fox, Marlon D Cowart

Mol Interv· April 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Histamine in cardiac sympathetic ganglia: a novel neurotransmitter?
Ryan M Fryer, Glenn A Reinhart, Timothy A Esbenshade

Mol Interv· February 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis