Publications by authors named "Robin Shapiro"

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A (14)C-leucine absorption, distribution, metabolism and excretion (ADME) study in adult Sprague-Dawley rat reveals β-hydroxy-β-methylbutyrate as a metabolite.
Anthony J Lee, David W A Beno, Xiaolin Zhang, Robin Shapiro, Mark Mason

Amino Acids· May 2015

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Identification of diamino chromone-2-carboxamides as MCHr1 antagonists with minimal hERG channel activity.
Andrew S Judd, Andrew J Souers, Dariusz Wodka, Gang Zhao, Mathew M Mulhern, Robin Shapiro

Bioorg Med Chem Lett· April 2007

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Constrained 7-fluorocarboxychromone-4-aminopiperidine based Melanin-concentrating hormone receptor 1 antagonists: the effects of chirality on substituted indan-1-ylamines.
Andrew J Souers, Rajesh R Iyengar, Andrew S Judd, David W A Beno, Ju Gao, Robin Shapiro

Bioorg Med Chem Lett· February 2007

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Discovery of orally active butyrolactam 11beta-HSD1 inhibitors.
Vince S C Yeh, Ravi Kurukulasuriya, Steven Fung, Katina Monzon, William Chiou, Robin Shapiro

Bioorg Med Chem Lett· November 2006

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Optimization of chromone-2-carboxamide melanin concentrating hormone receptor 1 antagonists: assessment of potency, efficacy, and cardiovascular safety.
John K Lynch, Jennifer C Freeman, Andrew S Judd, Rajesh Iyengar, Mathew Mulhern, Robin Shapiro

J Med Chem· November 2006

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Discovery and pharmacological evaluation of growth hormone secretagogue receptor antagonists.
Zhili Xin, Michael D Serby, Hongyu Zhao, Christi Kosogof, Bruce G Szczepankiewicz, Robin Shapiro

J Med Chem· July 2006

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2,4-diaminopyrimidine derivatives as potent growth hormone secretagogue receptor antagonists.
Michael D Serby, Hongyu Zhao, Bruce G Szczepankiewicz, Christi Kosogof, Zhili Xin, Robin Shapiro

J Med Chem· April 2006

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Chronic treatment with either dexfenfluramine or sibutramine in diet-switched diet-induced obese mice.
Eugene N Bush, Robin Shapiro, Michael E Brune, Victoria E Knourek-Segel, Brian A Droz

Endocrine· April 2006

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Aminopiperidine indazoles as orally efficacious melanin concentrating hormone receptor-1 antagonists.
Anil Vasudevan, Andrew J Souers, Jennifer C Freeman, Mary K Verzal, Ju Gao, Robin D Shapiro

Bioorg Med Chem Lett· December 2005

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Identification of ortho-amino benzamides and nicotinamides as MCHr1 antagonists.
Anil Vasudevan, Matthew J LaMarche, Christopher Blackburn, Jennifer Lee Che, Courtney A Luchaco-Cullis, Robin D Shapiro

Bioorg Med Chem Lett· October 2005

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Discovery and characterization of aminopiperidinecoumarin melanin concentrating hormone receptor 1 antagonists.
Philip R Kym, Rajesh Iyengar, Andrew J Souers, John K Lynch, Andrew S Judd, Robin Shapiro

J Med Chem· September 2005

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Synthesis and evaluation of urea-based indazoles as melanin-concentrating hormone receptor 1 antagonists for the treatment of obesity.
Andrew J Souers, Ju Gao, Dariusz Wodka, Andrew S Judd, Mathew M Mulhern, Robin Shapiro

Bioorg Med Chem Lett· June 2005

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Identification of 2-(4-benzyloxyphenyl)-N- [1-(2-pyrrolidin-1-yl-ethyl)-1H-indazol-6-yl]acetamide, an orally efficacious melanin-concentrating hormone receptor 1 antagonist for the treatment of obesity.
Andrew J Souers, Ju Gao, Michael Brune, Eugene Bush, Dariusz Wodka, Robin Shapiro

J Med Chem· March 2005

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Antiobesity effects of A-331440, a novel non-imidazole histamine H3 receptor antagonist.
Arthur A Hancock, Youssef L Bennani, Eugene N Bush, Timothy A Esbenshade, Ramin Faghih, Robin Shapiro

Eur J Pharmacol· March 2004

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