Publications by authors named "Steven Fung"

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Discovery of adamantane ethers as inhibitors of 11beta-HSD-1: Synthesis and biological evaluation.
Jyoti R Patel, Qi Shuai, Jurgen Dinges, Marty Winn, Marina Pliushchev, Steven Fung

Bioorg Med Chem Lett· February 2007

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Adamantane sulfone and sulfonamide 11-beta-HSD1 Inhibitors.
Bryan Sorensen, Martin Winn, Jeff Rohde, Qi Shuai, Jiahong Wang, Steven Fung

Bioorg Med Chem Lett· January 2007

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Parallel strategies for the preparation and selection of liver-targeted glucocorticoid receptor antagonists.
Bradley J Backes, Gregory L Hamilton, Phong Nguyen, Denise Wilcox, Steven Fung

Bioorg Med Chem Lett· January 2007

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Discovery and metabolic stabilization of potent and selective 2-amino-N-(adamant-2-yl) acetamide 11beta-hydroxysteroid dehydrogenase type 1 inhibitors.
Jeffrey J Rohde, Marina A Pliushchev, Bryan K Sorensen, Dariusz Wodka, Qi Shuai, Steven Fung

J Med Chem· January 2007

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Synthesis and activity of novel bile-acid conjugated glucocorticoid receptor antagonists.
Steven J Richards, Thomas W von Geldern, Peer Jacobson, Denise Wilcox, Phong Nguyen, Steven Fung

Bioorg Med Chem Lett· December 2006

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Adamantane 11-beta-HSD-1 inhibitors: Application of an isocyanide multicomponent reaction.
Bryan Sorensen, Jeff Rohde, Jiahong Wang, Steven Fung, Katina Monzon

Bioorg Med Chem Lett· December 2006

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Discovery of potent and selective inhibitors of 11beta-HSD1 for the treatment of metabolic syndrome.
Steven Richards, Bryan Sorensen, Hwan-Soo Jae, Marty Winn, Yixian Chen, Steven Fung

Bioorg Med Chem Lett· December 2006

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Discovery of orally active butyrolactam 11beta-HSD1 inhibitors.
Vince S C Yeh, Ravi Kurukulasuriya, Steven Fung, Katina Monzon, William Chiou

Bioorg Med Chem Lett· November 2006

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Synthesis and structural activity relationship of 11beta-HSD1 inhibitors with novel adamantane replacements.
Vince S C Yeh, Ravi Kurukulasuriya, David Madar, Jyoti R Patel, Steven Fung

Bioorg Med Chem Lett· October 2006

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Synthesis and biological evaluation of heterocycle containing adamantane 11beta-HSD1 inhibitors.
Vince S C Yeh, Jyoti R Patel, Hong Yong, Ravi Kurukulasuriya, Steven Fung

Bioorg Med Chem Lett· October 2006

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Antidiabetic activity of passive nonsteroidal glucocorticoid receptor modulators.
J T Link, Bryan Sorensen, Jyoti Patel, Marlena Grynfarb, Annika Goos-Nilsson, Steven Fung

J Med Chem· August 2005

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Hepatic glucocorticoid receptor antagonism is sufficient to reduce elevated hepatic glucose output and improve glucose control in animal models of type 2 diabetes.
Peer B Jacobson, Thomas W von Geldern, Lars Ohman, Marie Osterland, Jiahong Wang, Steven Fung

J Pharmacol Exp Ther· July 2005

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Synthesis, activity, metabolic stability, and pharmacokinetics of glucocorticoid receptor modulator-statin hybrids.
J T Link, Bryan K Sorensen, Chunqiu Lai, Jiahong Wang, Steven Fung

Bioorg Med Chem Lett· August 2004

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Liver-selective glucocorticoid antagonists: a novel treatment for type 2 diabetes.
Thomas W von Geldern, Noah Tu, Philip R Kym, James T Link, Hwan-Soo Jae, Steven Fung

J Med Chem· August 2004

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