Publications by authors named "Brydon Bennett"

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Treatment of pemphigus and other neglected skin conditions with PC111, a human anti-Fas Ligand monoclonal antibody: a potential disease modifier.
Roberta Lotti, Antonino Amato, Brydon Bennett, Tommaso Zanocco-Marani, Alessandra Marconi

J Dermatolog Treat· December 2025

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Advancements in Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Treatment: Utilizing Fas-FasL Inhibition to Target Cell Death Signaling Pathways for Practical Human Application.
Yuki Saito, Roberta Lotti, Haruna Kimura, Akito Hasegawa, Brydon Bennett

J Invest Dermatol· April 2025

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Correction to "Discovery of the Selective Protein Kinase C-θ Kinase Inhibitor, CC-90005".
Patrick Papa, Brandon Whitefield, Deborah S Mortensen, Dan Cashion, Dehua Huang, Brydon Bennett

J Med Chem· December 2024

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Corrigendum: Blocking soluble Fas Ligand ameliorates pemphigus: PC111 efficacy in ex-vivo human pemphigus models.
Roberta Lotti, Jennifer E Hundt, Ralf J Ludwig, Christoph M Hammers, Brydon Bennett

Front Immunol· January 2024

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Blocking soluble Fas Ligand ameliorates pemphigus: PC111 efficacy in ex-vivo human pemphigus models.
Roberta Lotti, Jennifer E Hundt, Ralf J Ludwig, Christoph M. Hammers, Brydon Bennett

Front Immunol· July 2023

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Discovery of the c-Jun N-Terminal Kinase Inhibitor .
Mark A Nagy, Robert Hilgraf, Deborah S Mortensen, Jan Elsner, Stephen Norris, Brydon L Bennett

J Med Chem· December 2021

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Discovery of the Selective Protein Kinase C-θ Kinase Inhibitor, CC-90005.
Patrick Papa, Brandon Whitefield, Deborah S Mortensen, Dan Cashion, Dehua Huang, Brydon Bennett

J Med Chem· August 2021

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Targeting the Wnt signaling pathway through R-spondin 3 identifies an anti-fibrosis treatment strategy for multiple organs.
Mingjun Zhang, Michael Haughey, Nai-Yu Wang, Kate Blease, Ann M Kapoun, Brydon Bennett

PLoS One· July 2020

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JNK inhibition reduces lung remodeling and pulmonary fibrotic systemic markers.
Jos L J van der Velden, Ying Ye, James D Nolin, Sidra M Hoffman, David G Chapman, Brydon Bennett

Clin Transl Med· December 2016

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A Novel Triazolopyridine-Based Spleen Tyrosine Kinase Inhibitor That Arrests Joint Inflammation.
Gregory D Ferguson, Mercedes Delgado, Veronique Plantevin-Krenitsky, Kristen Jensen-Pergakes, R J Bates, Brydon Bennett

PLoS One· July 2016

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Jun N-terminal kinase as a potential molecular target for prevention and treatment of dermal fibrosis.
Nicole Reich, Michal Tomcik, Pawel Zerr, Veronika Lang, Clara Dees, Brydon L Bennett

Ann Rheum Dis· May 2012

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Evaluation of JNK blockade as an early intervention treatment for type 1 diabetic nephropathy in hypertensive rats.
Andy K H Lim, Frank Y Ma, David J Nikolic-Paterson, Elyce Ozols, Morag J Young, Brydon L Bennett

Am J Nephrol· March 2012

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Aminopurine based JNK inhibitors for the prevention of ischemia reperfusion injury.
Véronique Plantevin Krenitsky, Mercedes Delgado, Lisa Nadolny, Kiran Sahasrabudhe, Leticia Ayala, Brydon Bennett

Bioorg Med Chem Lett· February 2012

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Discovery of CC-930, an orally active anti-fibrotic JNK inhibitor.
Véronique Plantevin Krenitsky, Lisa Nadolny, Mercedes Delgado, Leticia Ayala, Steven S Clareen, Brydon Bennett

Bioorg Med Chem Lett· February 2012

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JNK signalling in human and experimental renal ischaemia/reperfusion injury.
John Kanellis, Frank Y Ma, Rangi Kandane-Rathnayake, John P Dowling, Kevan R Polkinghorne, Brydon L Bennett

Nephrol Dial Transplant· September 2010

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Immunomodulatory drugs reorganize cytoskeleton by modulating Rho GTPases.
Yibing Xu, Jianwu Li, Gregory D Ferguson, Frank Mercurio, Gody Khambatta, Brydon L Bennett

Blood· July 2009

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Blockade of the c-Jun amino terminal kinase prevents crescent formation and halts established anti-GBM glomerulonephritis in the rat.
Frank Y Ma, Robert S Flanc, Greg H Tesch, Brydon L Bennett, Glenn C Friedman

Lab Invest· April 2009

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CC-4047 promotes Th1 cell differentiation and reprograms polarized human Th2 cells by enhancing transcription factor T-bet.
Weiming Xu, Maria Celeridad, Sabita Sankar, David R Webb, Brydon L Bennett

Clin Immunol· September 2008

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Attenuation of ozone-induced airway inflammation and hyper-responsiveness by c-Jun NH2 terminal kinase inhibitor SP600125.
Alison S Williams, Razao Issa, Sum Yee Leung, Puneeta Nath, Gregory D Ferguson, Brydon L Bennett

J Pharmacol Exp Ther· July 2007

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Suppression of alloreactivity and allograft rejection by SP600125, a small molecule inhibitor of c-Jun N-terminal kinase.
Akihiro Tabata, Masayuki Morikawa, Masahiro Miyajima, Brydon L Bennett, Yoshitaka Satoh

Transplantation· May 2007

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A pathogenic role for c-Jun amino-terminal kinase signaling in renal fibrosis and tubular cell apoptosis.
Frank Y Ma, Robert S Flanc, Greg H Tesch, Yingjie Han, Robert C Atkins, Brydon L Bennett

J Am Soc Nephrol· February 2007

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Pro-inflammatory signaling by Jun-N-terminal kinase in inflammatory bowel disease.
Keiichi Mitsuyama, Asuka Suzuki, Nobuo Tomiyasu, Osamu Tsuruta, Shigehiko Kitazaki, Brydon L Bennett

Int J Mol Med· March 2006

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JNK mediates hepatic ischemia reperfusion injury.
Tetsuya Uehara, Brydon Bennett, Steve T Sakata, Yoshitaka Satoh, Graham K Bilter

J Hepatol· June 2005

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Potential role of c-Jun NH2-terminal kinase in allergic airway inflammation and remodelling: effects of SP600125.
Puneeta Nath, Paul Eynott, Sum-Yee Leung, Ian M Adcock, Brydon L Bennett

Eur J Pharmacol· January 2005

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c-Jun N-terminal kinase mediates hepatic injury after rat liver transplantation.
Tetsuya Uehara, Xing Xi Peng, Brydon Bennett, Yoshi Satoh, Glenn Friedman

Transplantation· August 2004

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