Publications by authors named "Carl Poisson"

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Discovery of Novel Thiophene-Based, Thumb Pocket 2 Allosteric Inhibitors of the Hepatitis C NS5B Polymerase with Improved Potency and Physicochemical Profiles.
John J Court, Carl Poisson, Andrzej Ardzinski, Darius Bilimoria, Laval Chan

J Med Chem· July 2016

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Synthesis and evaluation of NS5A inhibitors containing diverse heteroaromatic cores.
James A Henderson, Darius Bilimoria, Monica Bubenik, Caroline Cadilhac, Kevin M Cottrell, Carl Poisson

Bioorg Med Chem Lett· February 2015

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Benzimidazole-containing HCV NS5A inhibitors: effect of 4-substituted pyrrolidines in balancing genotype 1a and 1b potency.
James A Henderson, Darius Bilimoria, Monica Bubenik, Caroline Cadilhac, Kevin M Cottrell, Carl Poisson

Bioorg Med Chem Lett· February 2015

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HCV NS5B polymerase-bound conformation of a soluble sulfonamide inhibitor by 2D transferred NOESY.
Constantin G Yannopoulos, Ping Xu, Feng Ni, Laval Chan, Oswy Z Pereira, Carl Poisson

Bioorg Med Chem Lett· November 2004

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Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 1: Sulfonamides.
Laval Chan, Sanjoy K Das, T Jagadeeswar Reddy, Carl Poisson, Mélanie Proulx

Bioorg Med Chem Lett· February 2004

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Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 2: tertiary amides.
Laval Chan, Oswy Pereira, T Jagadeeswar Reddy, Sanjoy K Das, Carl Poisson

Bioorg Med Chem Lett· February 2004

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Further SAR studies on novel small molecule inhibitors of the hepatitis C (HCV) NS5B polymerase.
T Jagadeeswar Reddy, Laval Chan, Nathalie Turcotte, Melanie Proulx, Oswy Z Pereira, Carl Poisson

Bioorg Med Chem Lett· October 2003

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Identification of N,N-disubstituted phenylalanines as a novel class of inhibitors of hepatitis C NS5B polymerase.
Laval Chan, T Jagadeeswar Reddy, Mélanie Proulx, Sanjoy K Das, Oswy Pereira, Carl Poisson

J Med Chem· April 2003

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