Publications by authors named "Carol Routledge"

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Drug repurposing for Alzheimer's disease: a Delphi consensus and stakeholder consultation.
Anne Corbett, Janet Sultana, Kate Stych, Roger Mills, Jeff L Cummings, Carol Routledge

Alzheimers Res Ther· November 2025

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Safety, tolerability, pharmacodynamic and wellbeing effects of SPL026 (dimethyltryptamine fumarate) in healthy participants: a randomized, placebo-controlled phase 1 trial.
Ellen James, David Erritzoe, Tiffanie Benway, Zelah Joel, Christopher Timmermann, Carol Routledge

Front Psychiatry· January 2024

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Discovery and Characterization of SPL028: Deuterated ,-Dimethyltryptamine.
Marie Layzell, Peter Rands, Meghan Good, Zelah Joel, Rick Cousins, Carol Routledge

ACS Med Chem Lett· September 2023

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Pharmacokinetics of N,N-dimethyltryptamine in Humans.
Meghan Good, Zelah Joel, Tiffanie Benway, Carol Routledge, Chris Timmermann

Eur J Drug Metab Pharmacokinet· May 2023

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Recommendations to address key recruitment challenges of Alzheimer's disease clinical trials.
Jessica B Langbaum, Julie Zissimopoulos, Rhoda Au, Niranjan Bose, Chris J Edgar, Carol Routledge

Alzheimers Dement· February 2023

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Inhibition of IL-34 Unveils Tissue-Selectivity and Is Sufficient to Reduce Microglial Proliferation in a Model of Chronic Neurodegeneration.
Juliane Obst, Emilie Simon, Maria Martin-Estebane, Elena Pipi, Liana M Barkwill, Carol Routledge

Front Immunol· June 2021

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Potential human transmission of amyloid β pathology: surveillance and risks.
Elsa Lauwers, Giovanna Lalli, Sebastian Brandner, John Collinge, Veerle Compernolle, Carol Routledge

Lancet Neurol· October 2020

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Tackling gaps in developing life-changing treatments for dementia.
Rui Mauricio, Caroline Benn, John Davis, Gerry Dawson, Lee A Dawson, Carol Routledge

Alzheimers Dement (N Y)· June 2019

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Development of a characterised tool kit for the interrogation of NLRP3 inflammasome-dependent responses.
Elena Redondo-Castro, Dorte Faust, Simon Fox, Alex G Baldwin, Simon Osborne, Carol Routledge

Sci Rep· April 2018

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Effect of the acute and chronic administration of the selective 5-HT6 receptor antagonist SB-271046 on the activity of midbrain dopamine neurons in rats: an in vivo electrophysiological study.
Yoshio Minabe, Yukihiko Shirayama, Kenji Hashimoto, Carol Routledge, Jim J Hagan

Synapse· April 2004

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Two macroscopic and microscopic brain imaging studies of human hippocampus in early Alzheimer's disease and schizophrenia research.
Nicholas Lange, Stephen Lake, Reisa Sperling, John Brown, Carol Routledge

Stat Med· January 2004

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Practice and difficulty evoke anatomically and pharmacologically dissociable brain activation dynamics.
Ed Bullmore, John Suckling, Fernando Zelaya, Chris Long, Garry Honey, Carol Routledge

Cereb Cortex· February 2003

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Bicyclic piperazinylbenzenesulphonamides are potent and selective 5-HT6 receptor antagonists.
Steven M Bromidge, Stephen E Clarke, Frank D King, Peter J Lovell, Helen Newman, Carol Routledge

Bioorg Med Chem Lett· May 2002

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The distribution of 5-HT(6) receptors in rat brain: an autoradiographic binding study using the radiolabelled 5-HT(6) receptor antagonist [(125)I]SB-258585.
Jennifer C Roberts, Charlie Reavill, Simon Z East, Paul J Harrison, Sara Patel, Carol Routledge

Brain Res· April 2002

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Functional MRI detection of pharmacologically induced memory impairment.
Reisa Sperling, Douglas Greve, Anders Dale, Ronald Killiany, Jennifer Holmes, Carol Routledge

Proc Natl Acad Sci U S A· January 2002

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