Publications by authors named "Chad Dickey"

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Shannon E Hill, David Beaulieu-Abdelahad, Andrea Lemus, Jack M Webster, Santiago Rodriguez Ospina, Chad A Dickey

ACS Chem Biol· May 2023

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Chaperoning activity of the cyclophilin family prevents tau aggregation.
Shannon E Hill, Abigail R Esquivel, Santiago Rodriguez Ospina, Lauren M Rahal, Chad A Dickey

Protein Sci· November 2022

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Small Heat Shock Protein 22 Improves Cognition and Learning in the Tauopathic Brain.
Santiago Rodriguez Ospina, Danielle M Blazier, Marangelie Criado-Marrero, Lauren A Gould, Niat T Gebru, Chad A Dickey

Int J Mol Sci· January 2022

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Small heat shock protein 22 kDa can modulate the aggregation and liquid-liquid phase separation behavior of tau.
April L Darling, Jan Dahrendorff, Stefan G Creodore, Chad A Dickey, Laura J Blair

Protein Sci· July 2021

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FKBP52 overexpression accelerates hippocampal-dependent memory impairments in a tau transgenic mouse model.
Marangelie Criado-Marrero, Niat T Gebru, Lauren A Gould, Danielle M Blazier, Yamile Vidal-Aguiar, Chad A Dickey

NPJ Aging Mech Dis· May 2021

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Aberrant AZIN2 and polyamine metabolism precipitates tau neuropathology.
Leslie A Sandusky-Beltran, Andrii Kovalenko, Devon S Placides, Kevin Ratnasamy, Chao Ma, Chad A Dickey

J Clin Invest· February 2021

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FKBP5 and early life stress affect the hippocampus by an age-dependent mechanism.
Marangelie Criado-Marrero, Taylor M Smith, Lauren A Gould, Sojeong Kim, Hannah J Penny, Chad A Dickey

Brain Behav Immun Health· December 2020

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Hsp22 with an N-Terminal Domain Truncation Mediates a Reduction in Tau Protein Levels.
Jack M Webster, April L Darling, Taylor A Sanders, Danielle M Blazier, Yamile Vidal-Aguiar, Chad A Dickey

Int J Mol Sci· July 2020

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Management of Hsp90-Dependent Protein Folding by Small Molecules Targeting the Aha1 Co-Chaperone.
Jay K Singh, Darren M Hutt, Bradley Tait, Naihsuan C Guy, Jeffrey C Sivils, Chad Dickey

Cell Chem Biol· March 2020

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Hippocampal Neurogenesis Is Enhanced in Adult Tau Deficient Mice.
Marangelie Criado-Marrero, Jonathan J Sabbagh, Margaret R Jones, Dale Chaput, Chad A Dickey

Cells· January 2020

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Stable calcium-free myocilin olfactomedin domain variants reveal challenges in differentiating between benign and glaucoma-causing mutations.
Shannon E Hill, Michelle S Kwon, Mackenzie D Martin, Amirthaa Suntharalingam, Anthony Hazel, Chad A Dickey

J Biol Chem· August 2019

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Early Life Stress and High FKBP5 Interact to Increase Anxiety-Like Symptoms through Altered AKT Signaling in the Dorsal Hippocampus.
Marangelie Criado-Marrero, Niat T Gebru, Lauren A Gould, Taylor M Smith, Sojeong Kim, Chad A Dickey

Int J Mol Sci· June 2019

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Spermidine/spermine-N-acetyltransferase ablation impacts tauopathy-induced polyamine stress response.
Leslie A Sandusky-Beltran, Andrii Kovalenko, Chao Ma, John Ivan T Calahatian, Devon S Placides, Chad A Dickey

Alzheimers Res Ther· June 2019

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Repeated repeat problems: Combinatorial effect of C9orf72-derived dipeptide repeat proteins.
April L Darling, Leonid Breydo, Emma G Rivas, Niad T Gebru, Dali Zheng, Chad A Dickey

Int J Biol Macromol· April 2019

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The Disease-Associated Chaperone FKBP51 Impairs Cognitive Function by Accelerating AMPA Receptor Recycling.
Laura J Blair, Marangelie Criado-Marrero, Dali Zheng, Xinming Wang, Siddharth Kamath, Chad A Dickey

eNeuro· April 2019

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Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex.
Javier Oroz, Bliss J Chang, Piotr Wysoczanski, Chung-Tien Lee, Ángel Pérez-Lara, Chad A Dickey

Nat Commun· October 2018

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Targeting the FKBP51/GR/Hsp90 Complex to Identify Functionally Relevant Treatments for Depression and PTSD.
Jonathan J Sabbagh, Ricardo A Cordova, Dali Zheng, Marangelie Criado-Marrero, Andrea Lemus, Chad A Dickey

ACS Chem Biol· August 2018

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Mapping interactions with the chaperone network reveals factors that protect against tau aggregation.
Sue-Ann Mok, Carlo Condello, Rebecca Freilich, Anne Gillies, Taylor Arhar, Chad A Dickey

Nat Struct Mol Biol· May 2018

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Trifunctional High-Throughput Screen Identifies Promising Scaffold To Inhibit Grp94 and Treat Myocilin-Associated Glaucoma.
Dustin J E Huard, Vincent M Crowley, Yuhong Du, Ricardo A Cordova, Zheying Sun, Chad A Dickey

ACS Chem Biol· April 2018

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Isoform-selective Hsp90 inhibition rescues model of hereditary open-angle glaucoma.
Andrew R Stothert, Amirthaa Suntharalingam, Xiaolan Tang, Vincent M Crowley, Sanket J Mishra, Chad A Dickey

Sci Rep· December 2017

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Enhanced tau pathology via RanBP9 and Hsp90/Hsc70 chaperone complexes.
Jung A Woo, Tian Liu, Xingyu Zhao, Courtney Trotter, Ksenia Yrigoin, Chad Dickey

Hum Mol Genet· October 2017

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Hsp90 activator Aha1 drives production of pathological tau aggregates.
Lindsey B Shelton, Jeremy D Baker, Dali Zheng, Leia E Sullivan, Parth K Solanki, Chad A Dickey

Proc Natl Acad Sci U S A· September 2017

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Human cyclophilin 40 unravels neurotoxic amyloids.
Jeremy D Baker, Lindsey B Shelton, Dali Zheng, Filippo Favretto, Bryce A Nordhues, Chad A Dickey

PLoS Biol· June 2017

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Transformation of the Non-Selective Aminocyclohexanol-Based Hsp90 Inhibitor into a Grp94-Seletive Scaffold.
Sanket J Mishra, Suman Ghosh, Andrew R Stothert, Chad A Dickey, Brian S J Blagg

ACS Chem Biol· January 2017

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Stabilizing the Hsp70-Tau Complex Promotes Turnover in Models of Tauopathy.
Zapporah T Young, Jennifer N Rauch, Victoria A Assimon, Umesh K Jinwal, Misol Ahn, Chad A Dickey

Cell Chem Biol· August 2016

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