Publications by authors named "Charles D Thompson"

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Tips for Office Procedural Coding: Developed by the AUGS Coding Committee.
Charles D Thompson

Urogynecology (Phila)· October 2025

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Clinical Pharmacokinetics of Ponesimod, a Selective S1P1 Receptor Modulator, in the Treatment of Multiple Sclerosis.
Terra M Kruger, Belén Valenzuela, Charles D Thompson, Sivi Ouwerkerk-Mahadevan, Juan Jose Perez Ruixo

Clin Pharmacokinet· November 2023

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Bladder calculi causing irreducible urogenital prolapse.
Charles D Thompson, Bennett E Henderson, Russell Stanley

BMJ Case Rep· September 2018

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MK-7622: A First-in-Class M Positive Allosteric Modulator Development Candidate.
Douglas C Beshore, Christina N Di Marco, Ronald K Chang, Thomas J Greshock, Lei Ma, Charles D Thompson

ACS Med Chem Lett· July 2018

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Do clinicians receive adequate training to identify trafficked persons? A scoping review of NHS Foundation Trusts.
Charles Dr Thompson, Arun Mahay, David Stuckler, Sarah Steele

JRSM Open· September 2017

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siRNA-mediated knockdown of P450 oxidoreductase in rats: a tool to reduce metabolism by CYPs and increase exposure of high clearance compounds.
Rob S Burke, Inthirai Somasuntharam, Paul Rearden, Duncan Brown, Sujal V Deshmukh, Charles D Thompson

Pharm Res· December 2014

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Discovery of naphthyl-fused 5-membered lactams as a new class of m1 positive allosteric modulators.
Zhi-Qiang Yang, Youheng Shu, Lei Ma, Marion Wittmann, William J Ray, Charles D Thompson

ACS Med Chem Lett· May 2014

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Identification of a methoxynaphthalene scaffold as a core replacement in quinolizidinone amide M(1) positive allosteric modulators.
Scott D Kuduk, Christina N Di Marco, Jonathan R Saffold, William J Ray, Lei Ma, Charles D Thompson

Bioorg Med Chem Lett· March 2014

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The preclinical efficacy, selectivity and pharmacologic profile of MK-5932, an insulin-sparing selective glucocorticoid receptor modulator.
Philip E Brandish, Kenneth Anderson, Gretchen A Baltus, Chang Bai, Christopher J Bungard, Charles D Thompson

Eur J Pharmacol· February 2014

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Metabolites of PPI-2458, a selective, irreversible inhibitor of methionine aminopeptidase-2: structure determination and in vivo activity.
Christopher C Arico-Muendel, Bruce Belanger, Dennis Benjamin, Heather S Blanchette, Teresa M Caiazzo, Charles D Thompson

Drug Metab Dispos· April 2013

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Orally active fumagillin analogues: transformations of a reactive warhead in the gastric environment.
Christopher C Arico-Muendel, Heather Blanchette, Dennis R Benjamin, Teresa M Caiazzo, Paolo A Centrella, Charles D Thompson

ACS Med Chem Lett· April 2013

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Identification of amides as carboxylic Acid surrogates for quinolizidinone-based m1 positive allosteric modulators.
Scott D Kuduk, Ronald K Chang, Thomas J Greshock, William J Ray, Lei Ma, Charles D Thompson

ACS Med Chem Lett· December 2012

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Discovery of selective glucocorticoid receptor modulator MK-5932.
Christopher J Bungard, George D Hartman, Jesse J Manikowski, James J Perkins, Chang Bai, Charles D Thompson

Bioorg Med Chem· December 2011

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Discovery of a selective allosteric M1 receptor modulator with suitable development properties based on a quinolizidinone carboxylic acid scaffold.
Scott D Kuduk, Ronald K Chang, Christina N Di Marco, Daniel R Pitts, Thomas J Greshock, Charles D Thompson

J Med Chem· July 2011

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Fused heterocyclic M1 positive allosteric modulators.
Scott D Kuduk, Christina N Di Marco, Victoria Cofre, William J Ray, Lei Ma, Charles D Thompson

Bioorg Med Chem Lett· May 2011

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Quinolizidinone carboxylic acid selective M1 allosteric modulators: SAR in the piperidine series.
Scott D Kuduk, Ronald K Chang, Christina N Di Marco, William J Ray, Lei Ma, Charles D Thompson

Bioorg Med Chem Lett· March 2011

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Quinolizidinone carboxylic acids as CNS penetrant, selective m1 allosteric muscarinic receptor modulators.
Scott D Kuduk, Ronald K Chang, Christina N Di Marco, William J Ray, Lei Ma, Charles D Thompson

ACS Med Chem Lett· September 2010

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Heterocyclic fused pyridone carboxylic acid M(1) positive allosteric modulators.
Scott D Kuduk, Christina N Di Marco, Ronald K Chang, William J Ray, Lei Ma, Charles D Thompson

Bioorg Med Chem Lett· April 2010

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Hydroxy cycloalkyl fused pyridone carboxylic acid M(1) positive allosteric modulators.
Scott D Kuduk, Robert M DiPardo, Douglas C Beshore, William J Ray, Lei Ma, Charles D Thompson

Bioorg Med Chem Lett· April 2010

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N-heterocyclic derived M1 positive allosteric modulators.
Scott D Kuduk, Christina N Di Marco, Victoria Cofre, Daniel R Pitts, William J Ray, Charles D Thompson

Bioorg Med Chem Lett· February 2010

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Carbamate analogues of fumagillin as potent, targeted inhibitors of methionine aminopeptidase-2.
Christopher C Arico-Muendel, Dennis R Benjamin, Teresa M Caiazzo, Paolo A Centrella, Brooke D Contonio, Charles D Thompson

J Med Chem· December 2009

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Inhibition of melanoma tumor growth by a pharmacological inhibitor of MetAP-2, PPI-2458.
Gerhard Hannig, Douglas D Lazarus, Sylvie G Bernier, Russell M Karp, Jeanine Lorusso, Charles D Thompson

Int J Oncol· April 2006

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A novel methionine aminopeptidase-2 inhibitor, PPI-2458, inhibits non-Hodgkin's lymphoma cell proliferation in vitro and in vivo.
Andrew C Cooper, Russell M Karp, Edward J Clark, Nazbeh R Taghizadeh, Jennifer G Hoyt, Charles D Thompson

Clin Cancer Res· April 2006

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Methionine aminopeptidases type I and type II are essential to control cell proliferation.
Sylvie G Bernier, Nazbeh Taghizadeh, Charles D Thompson, William F Westlin, Gerhard Hannig

J Cell Biochem· August 2005

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A methionine aminopeptidase-2 inhibitor, PPI-2458, for the treatment of rheumatoid arthritis.
Sylvie G Bernier, Douglas D Lazarus, Edward Clark, Beth Doyle, Matthew T Labenski, Charles D Thompson

Proc Natl Acad Sci U S A· July 2004

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