Publications by authors named "Chengkai Dai"

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A textile-based alignment-free electrophysiological sensing sleeve for comprehensive cardiovascular monitoring.
Shirong Qiu, Yihao Li, Chengkai Dai, Shun Wu, Xiangjia Chen

Microsyst Nanoeng· November 2025

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Detection of the DNA binding of transcription factors in situ at the single-cell resolution in cultured cells by proximity ligation assay.
Babul Moni Ram, Chengkai Dai

STAR Protoc· December 2023

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Heat shock factor 1 (HSF1) specifically potentiates c-MYC-mediated transcription independently of the canonical heat shock response.
Meng Xu, Ling Lin, Babul Moni Ram, Omprakash Shriwas, Kun-Han Chuang, Siyuan Dai, Chengkai Dai

Cell Rep· June 2023

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A multi-axis robot-based bioprinting system supporting natural cell function preservation and cardiac tissue fabrication.
Zeyu Zhang, Chenming Wu, Chengkai Dai, Qingqing Shi, Guoxin Fang

Bioact Mater· December 2022

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Loss of heat shock factor 1 promotes hepatic stellate cell activation and drives liver fibrosis.
Asmita Choudhury, Anuradha Ratna, Arlene Lim, Rebecca M Sebastian, Christopher L Moore, Chengkai Dai

Hepatol Commun· October 2022

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Heat shock factor 1 is a direct anti-amyloid factor: connecting neurodegeneration and uncontrolled growth.
Zijian Tang, Chengkai Dai

Neural Regen Res· March 2022

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HSF1 physically neutralizes amyloid oligomers to empower overgrowth and bestow neuroprotection.
Zijian Tang, Kuo-Hui Su, Meng Xu, Chengkai Dai

Sci Adv· November 2020

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Heat Shock Factor 1 Is a Direct Antagonist of AMP-Activated Protein Kinase.
Kuo-Hui Su, Siyuan Dai, Zijian Tang, Meng Xu, Chengkai Dai

Mol Cell· November 2019

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Visualization of RAS/MAPK Signaling In Situ by the Proximity Ligation Assay (PLA).
Zijian Tang, Chengkai Dai

Methods Mol Biol· January 2018

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The heat-shock, or HSF1-mediated proteotoxic stress, response in cancer: from proteomic stability to oncogenesis.
Chengkai Dai

Philos Trans R Soc Lond B Biol Sci· January 2018

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mTORC1 senses stresses: Coupling stress to proteostasis.
Kuo-Hui Su, Chengkai Dai

Bioessays· May 2017

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Protein quantity-quality balance licenses growth.
Kuo-Hui Su, Chengkai Dai

Cell Cycle· December 2016

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Metabolic control of the proteotoxic stress response: implications in diabetes mellitus and neurodegenerative disorders.
Kuo-Hui Su, Chengkai Dai

Cell Mol Life Sci· November 2016

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HSF1 critically attunes proteotoxic stress sensing by mTORC1 to combat stress and promote growth.
Kuo-Hui Su, Junyue Cao, Zijian Tang, Siyuan Dai, Yishu He, Chengkai Dai

Nat Cell Biol· May 2016

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HSF1: Guardian of Proteostasis in Cancer.
Chengkai Dai, Stephen Byers Sampson

Trends Cell Biol· January 2016

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Suppression of the HSF1-mediated proteotoxic stress response by the metabolic stress sensor AMPK.
Siyuan Dai, Zijian Tang, Junyue Cao, Wei Zhou, Huawen Li, Chengkai Dai

EMBO J· February 2015

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MEK guards proteome stability and inhibits tumor-suppressive amyloidogenesis via HSF1.
Zijian Tang, Siyuan Dai, Yishu He, Rosalinda A Doty, Leonard D Shultz, Chengkai Dai

Cell· February 2015

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Metabolic stressors disrupt proteome homeostasis to suppress malignancy.
Chengkai Dai

Mol Cell Oncol· January 2015

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Loss of tumor suppressor NF1 activates HSF1 to promote carcinogenesis.
Chengkai Dai, Sandro Santagata, Zijian Tang, Jiayuan Shi, Junxia Cao

J Clin Invest· October 2012

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Proteotoxic stress of cancer: implication of the heat-shock response in oncogenesis.
Chengkai Dai, Siyuan Dai, Junyue Cao

J Cell Physiol· August 2012

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Sulforaphane activates heat shock response and enhances proteasome activity through up-regulation of Hsp27.
Nanqin Gan, Yu-Chieh Wu, Mathilde Brunet, Carmen Garrido, Fung-Lung Chung, Chengkai Dai

J Biol Chem· November 2010

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Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis.
Chengkai Dai, Luke Whitesell, Arlin B Rogers, Susan Lindquist

Cell· September 2007

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HSP90: a rising star on the horizon of anticancer targets.
Chengkai Dai, Luke Whitesell

Future Oncol· August 2005

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The characteristics of astrocytomas and oligodendrogliomas are caused by two distinct and interchangeable signaling formats.
Chengkai Dai, Yelena Lyustikman, Alan Shih, Xiaoyi Hu, Gregory N Fuller

Neoplasia· April 2005

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Overexpression of c-MYC promotes an undifferentiated phenotype in cultured astrocytes and allows elevated Ras and Akt signaling to induce gliomas from GFAP-expressing cells in mice.
Andrew B Lassman, Chengkai Dai, Gregory N Fuller, Andrew J Vickers, Eric C Holland

Neuron Glia Biol· May 2004

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