Publications by authors named "Christian Frey"

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Methamphetamine Overdose and Hyperthermia in a 41-Year-Old Man Found Unresponsive.
Christian G Frey, Bryan Wilson, Hailey P Hoffmann, John R Zatarain, Chiemela Ubani

Cureus· November 2025

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Innovation in Onychomycosis Treatment Through Creative Compounding.
Kristine Hoffman, Matthew Gorski, Christian P Frey

Cureus· September 2025

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Buprenorphine-Naloxone for Opioid Use Disorder: Reduction in Mortality and Increased Remission.
Krishna K Paul, Christian G Frey, Stanley Troung, Laura Vita Q Paglicawan, Kathryn A Cunningham

West J Emerg Med· November 2024

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Hepatobiliary long-term consequences of COVID-19: dramatically increased rate of secondary sclerosing cholangitis in critically ill COVID-19 patients.
Silke Leonhardt, Christian Jürgensen, Josephine Frohme, Donata Grajecki, Andreas Adler, Christian Frey

Hepatol Int· December 2023

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Therapeutic Potential of TLR8 Agonist GS-9688 (Selgantolimod) in Chronic Hepatitis B: Remodeling of Antiviral and Regulatory Mediators.
Oliver E Amin, Emily J Colbeck, Stephane Daffis, Shahzada Khan, Dhivya Ramakrishnan, Christian Frey

Hepatology· July 2021

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Serum HBsAg clearance has minimal impact on CD8+ T cell responses in mouse models of HBV infection.
Valeria Fumagalli, Pietro Di Lucia, Valentina Venzin, Elisa B Bono, Robert Jordan, Christian R Frey

J Exp Med· November 2020

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PD-1 blockade partially recovers dysfunctional virus-specific B cells in chronic hepatitis B infection.
Loghman Salimzadeh, Nina Le Bert, Charles-A Dutertre, Upkar S Gill, Evan W Newell, Christian Frey

J Clin Invest· October 2018

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The PI3Kδ-Selective Inhibitor Idelalisib Minimally Interferes with Immune Effector Function Mediated by Rituximab or Obinutuzumab and Significantly Augments B Cell Depletion In Vivo.
Adam Palazzo, Sylvia Herter, Laura Grosmaire, Randy Jones, Christian R Frey

J Immunol· April 2018

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Discovery of Potent Cyclophilin Inhibitors Based on the Structural Simplification of Sanglifehrin A.
Victoria A Steadman, Simon B Pettit, Karine G Poullennec, Linos Lazarides, Andrew J Keats, Christian R Frey

J Med Chem· February 2017

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TLR7 Agonist GS-9620 Is a Potent Inhibitor of Acute HIV-1 Infection in Human Peripheral Blood Mononuclear Cells.
Rujuta A Bam, Derek Hansen, Alivelu Irrinki, Andrew Mulato, Gregg S Jones, Christian R Frey

Antimicrob Agents Chemother· January 2017

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Intracellular Activation of Tenofovir Alafenamide and the Effect of Viral and Host Protease Inhibitors.
Gabriel Birkus, Rujuta A Bam, Madeleine Willkom, Christian R Frey, Luong Tsai

Antimicrob Agents Chemother· January 2016

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Pharmacokinetic and pharmacodynamic properties of GS-9620, a novel Toll-like receptor 7 agonist, demonstrate interferon-stimulated gene induction without detectable serum interferon at low oral doses.
Abigail Fosdick, Jim Zheng, Stefan Pflanz, Christian R Frey, Joseph Hesselgesser

J Pharmacol Exp Ther· January 2014

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Safety, pharmacokinetics and pharmacodynamics of GS-9620, an oral Toll-like receptor 7 agonist.
Uri Lopatin, Grushenka Wolfgang, Daniel Tumas, Christian R Frey, Carol Ohmstede

Antivir Ther· September 2013

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GS-9620, an oral agonist of Toll-like receptor-7, induces prolonged suppression of hepatitis B virus in chronically infected chimpanzees.
Robert E Lanford, Bernadette Guerra, Deborah Chavez, Luis Giavedoni, Vida L Hodara, Christian R Frey

Gastroenterology· June 2013

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Mutations in adenosine deaminase-like (ADAL) protein confer resistance to the antiproliferative agents N6-cyclopropyl-PMEDAP and GS-9219.
Christian R Frey, Graciela Andrei, Ivan Votruba, Carina Cannizzaro, Bin Han

Anticancer Res· May 2013

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Role of cathepsin A and lysosomes in the intracellular activation of novel antipapillomavirus agent GS-9191.
Gabriel Birkus, Nilima Kutty, Christian R Frey, Riri Shribata, Tsuifen Chou

Antimicrob Agents Chemother· May 2011

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Caspase-cleaved HPK1 induces CD95L-independent activation-induced cell death in T and B lymphocytes.
Dirk Brenner, Alexander Golks, Mareike Becker, Wolfgang Müller, Christian R Frey

Blood· December 2007

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Psychometric properties of an International Classification of Functioning, Disability and Health (ICF)-oriented, adaptive questionnaire for the assessment of mobility, self-care and domestic life.
Erik Farin, Annette Fleitz, Christian Frey

J Rehabil Med· September 2007

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Goals in cardiac rehabilitation: influencing factors, relation to outcome, and relevance of physicians' illness perception.
Erik Farin, Christian Frey, Manuela Glattacker, Wilfried H Jäckel

J Cardiopulm Rehabil Prev· July 2007

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Comparative cytotoxicity of alkyl gallates on mouse tumor cell lines and isolated rat hepatocytes.
Christian Frey, Mario Pavani, Gianni Cordano, Sergio Muñoz, Enrique Rivera

Comp Biochem Physiol A Mol Integr Physiol· April 2007

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Clinical and mechanistic aspects of glucocorticoid-induced chemotherapy resistance in the majority of solid tumors.
Chengwen Zhang, Till Wenger, Jürgen Mattern, Septimia Ilea, Christian Frey

Cancer Biol Ther· February 2007

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In vitro generated human memory-like T cells are CD95 type II cells and resistant towards CD95-mediated apoptosis.
Stefanie C Fas, Sven Baumann, Andreas Krueger, Christian R Frey, Henning Schulze-Bergkamen

Eur J Immunol· November 2006

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How T lymphocytes switch between life and death.
Rüdiger Arnold, Dirk Brenner, Mareike Becker, Christian R Frey, Peter H Krammer

Eur J Immunol· July 2006

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Hepatocyte growth factor induces Mcl-1 in primary human hepatocytes and inhibits CD95-mediated apoptosis via Akt.
Henning Schulze-Bergkamen, Dirk Brenner, Andreas Krueger, Dorothee Suess, Stefanie C Fas, Christian R Frey

Hepatology· March 2004

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Identification of CD8+ T cell epitopes in the immediate early 62 protein (IE62) of varicella-zoster virus, and evaluation of frequency of CD8+ T cell response to IE62, by use of IE62 peptides after varicella vaccination.
Christian R Frey, Margaret A Sharp, Andrew S Min, D Scott Schmid, Vladimir Loparev

J Infect Dis· July 2003

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