Publications by authors named "Christian Renn"

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Acyclic purine and pyrimidine nucleotide analogs as ecto-5'-nucleotidase (CD73) inhibitors.
Stephanie Federico, Christian Renn, Petra Brehova, Zlatko Janeba, Susanne Moschütz

Eur J Med Chem· September 2025

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Design, development and evaluation of a tritium-labeled radiotracer for ecto-5'-nucleotidase (CD73) - A versatile research tool and diagnostic agent for personalized medicine.
Riham M Idris, Haneen Al-Hroub, Constanze C Schmies, Patrick Riziki, Christian Renn

Biomed Pharmacother· July 2025

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Heparins are potent inhibitors of ectonucleotide pyrophosphatase/phospho-diesterase-1 (NPP1) - a promising target for the immunotherapy of cancer.
Vittoria Lopez, H J Maximilian Schuh, Salahuddin Mirza, Victoria J Vaaßen, Michael S Schmidt, Christian Renn

Front Immunol· September 2023

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Targeting two distinct epitopes on human CD73 with a bispecific antibody improves anticancer activity.
Odd L Gammelgaard, Mikkel G Terp, Christian Renn, Aran F Labrijn, Oliver Hamaker

J Immunother Cancer· September 2022

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Sulfated Polysaccharides from Macroalgae Are Potent Dual Inhibitors of Human ATP-Hydrolyzing Ectonucleotidases NPP1 and CD39.
Vittoria Lopez, Laura Schäkel, H J Maximilian Schuh, Michael S Schmidt, Salahuddin Mirza, Christian Renn

Mar Drugs· January 2021

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Fluorescent Probes for Ecto-5'-nucleotidase (CD73).
Constanze C Schmies, Georg Rolshoven, Riham M Idris, Karolina Losenkova, Christian Renn

ACS Med Chem Lett· November 2020

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2-Substituted α,β-Methylene-ADP Derivatives: Potent Competitive Ecto-5'-nucleotidase (CD73) Inhibitors with Variable Binding Modes.
Sanjay Bhattarai, Jan Pippel, Emma Scaletti, Riham Idris, Marianne Freundlieb, Christian Renn

J Med Chem· March 2020

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Adenine-(methoxy)-ethoxy-P-dithio-triphosphate inhibits pathologic calcium pyrophosphate deposition in osteoarthritic human chondrocytes.
Molhm Nassir, Salahuddin Mirza, Uri Arad, Sangyong Lee, Muhammad Rafehi, Christian Renn

Org Biomol Chem· November 2019

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Identification of adenine-N9-(methoxy)ethyl-β-bisphosphonate as NPP1 inhibitor attenuates NPPase activity in human osteoarthritic chondrocytes.
Molhm Nassir, Uri Arad, Sang-Yong Lee, Shani Journo, Salahuddin Mirza, Christian Renn

Purinergic Signal· June 2019

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Structure-Activity Relationship of Purine and Pyrimidine Nucleotides as Ecto-5'-Nucleotidase (CD73) Inhibitors.
Anna Junker, Christian Renn, Clemens Dobelmann, Vigneshwaran Namasivayam, Shanu Jain

J Med Chem· April 2019

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From Type I to Type II: Design, Synthesis, and Characterization of Potent Pyrazin-2-ones as DFG-Out Inhibitors of PDGFRβ.
Eugen Bethke, Boris Pinchuk, Christian Renn, Lydia Witt, Joachim Schlosser

ChemMedChem· December 2016

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Pharmacology of novel small-molecule tubulin inhibitors in glioblastoma cells with enhanced EGFR signalling.
Athena F Phoa, Stephen Browne, Fadi M S Gurgis, Mia C Åkerfeldt, Alexander Döbber, Christian Renn

Biochem Pharmacol· December 2015

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Design, Synthesis, and Characterization of a Photoactivatable Caged Prodrug of Imatinib.
Melanie Zindler, Boris Pinchuk, Christian Renn, Rebecca Horbert, Alexander Döbber

ChemMedChem· August 2015

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