Publications by authors named "Christian Rommel"

Claim this Profile
M
MLN0128, a novel mTOR kinase inhibitor, disrupts survival signaling and triggers apoptosis in AML and AML stem/ progenitor cells.
Zhihong Zeng, Rui-Yu Wang, Yi Hua Qiu, Duncan H Mak, Kevin Coombes, Christian Rommel

Oncotarget· August 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
PI3K and cancer: lessons, challenges and opportunities.
David A Fruman, Christian Rommel

Nat Rev Drug Discov· February 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
PI3K-δ and PI3K-γ inhibition by IPI-145 abrogates immune responses and suppresses activity in autoimmune and inflammatory disease models.
David G Winkler, Kerrie L Faia, Jonathan P DiNitto, Janid A Ali, Kerry F White, Christian Rommel

Chem Biol· November 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Selective inhibition of phosphoinositide 3-kinase p110α preserves lymphocyte function.
Lomon So, Sung Su Yea, Jean S Oak, Mengrou Lu, Arun Manmadhan, Christian Rommel

J Biol Chem· February 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Investigational drug MLN0128, a novel TORC1/2 inhibitor, demonstrates potent oral antitumor activity in human breast cancer xenograft models.
Yesim Gökmen-Polar, Yi Liu, Rachel A Toroni, Kerry L Sanders, Rutika Mehta, Christian Rommel

Breast Cancer Res Treat· December 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Targeting of mTORC1/2 by the mTOR kinase inhibitor PP242 induces apoptosis in AML cells under conditions mimicking the bone marrow microenvironment.
Zhihong Zeng, Yue Xi Shi, Twee Tsao, YiHua Qiu, Steven M Kornblau, Christian Rommel

Blood· September 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Dual mTORC1/2 and HER2 blockade results in antitumor activity in preclinical models of breast cancer resistant to anti-HER2 therapy.
Celina García-García, Yasir H Ibrahim, Violeta Serra, Maria Teresa Calvo, Marta Guzmán, Christian Rommel

Clin Cancer Res· May 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
PI3 kinase δ is a key regulator of synoviocyte function in rheumatoid arthritis.
Beatrix Bartok, David L Boyle, Yi Liu, Pingda Ren, Scott T Ball, Christian Rommel

Am J Pathol· May 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The translational landscape of mTOR signalling steers cancer initiation and metastasis.
Andrew C Hsieh, Yi Liu, Merritt P Edlind, Nicholas T Ingolia, Matthew R Janes, Christian Rommel

Nature· February 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Critical role for phosphoinositide 3-kinase gamma in parasite invasion and disease progression of cutaneous leishmaniasis.
Hannah E Cummings, Joseph Barbi, Patrick Reville, Steve Oghumu, Nicholas Zorko, Christian Rommel

Proc Natl Acad Sci U S A· January 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Defining the role of TORC1/2 in multiple myeloma.
Patricia Maiso, Yi Liu, Brittany Morgan, Abdel Kareem Azab, Pingda Ren, Christian Rommel

Blood· December 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
PI3Kδ inhibitors in cancer: rationale and serendipity merge in the clinic.
David A Fruman, Christian Rommel

Cancer Discov· December 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Next-generation flow cytometry.
Matthew R Janes, Christian Rommel

Nat Biotechnol· July 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
PI3K: from the bench to the clinic and back.
Bart Vanhaesebroeck, Peter K Vogt, Christian Rommel

Curr Top Microbiol Immunol· January 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Taking PI3Kδ and PI3Kγ one step ahead: dual active PI3Kδ/γ inhibitors for the treatment of immune-mediated inflammatory diseases.
Christian Rommel

Curr Top Microbiol Immunol· January 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Chemical inducers and transcriptional markers of oligodendrocyte differentiation.
Lara Joubert, Isabelle Foucault, Yves Sagot, Lilia Bernasconi, François Duval, Christian Rommel

J Neurosci Res· September 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The p110delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors.
Alex Berndt, Simon Miller, Olusegun Williams, Daniel D Le, Benjamin T Houseman, Christian Rommel

Nat Chem Biol· March 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor.
Matthew R Janes, Jose J Limon, Lomon So, Jing Chen, Raymond J Lim, Christian Rommel

Nat Med· February 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The p110 delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors.
Alex Berndt, Simon Miller, Olusegun Williams, Daniel D Le, Benjamin T Houseman, Christian Rommel

Nat Chem Biol· February 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Functional whole-genome analysis identifies Polo-like kinase 2 and poliovirus receptor as essential for neuronal differentiation upstream of the negative regulator alphaB-crystallin.
Cristina Draghetti, Catherine Salvat, Francisca Zanoguera, Marie-Laure Curchod, Chloé Vignaud, Christian Rommel

J Biol Chem· November 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
GLEPP1/protein-tyrosine phosphatase phi inhibitors block chemotaxis in vitro and in vivo and improve murine ulcerative colitis.
Rosanna Pescini Gobert, Monique van den Eijnden, Cedric Szyndralewiez, Catherine Jorand-Lebrun, Dominique Swinnen, Christian Rommel

J Biol Chem· April 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Leukocyte transmigration is modulated by chemokine-mediated PI3Kgamma-dependent phosphorylation of vimentin.
Laura Barberis, Christian Pasquali, Dominique Bertschy-Meier, Alessandra Cuccurullo, Carlotta Costa, Christian Rommel

Eur J Immunol· April 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Convergent functional genomics of oligodendrocyte differentiation identifies multiple autoinhibitory signaling circuits.
Rosanna Pescini Gobert, Lara Joubert, Marie-Laure Curchod, Catherine Salvat, Isabelle Foucault, Christian Rommel

Mol Cell Biol· March 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Chemokine receptor CCR2 undergoes transportin1-dependent nuclear translocation.
Nicolas Favre, Montserrat Camps, Christian Arod, Christian Chabert, Christian Rommel

Proteomics· November 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Phosphoinositide 3-kinase p110beta activity: key role in metabolism and mammary gland cancer but not development.
Elisa Ciraolo, Manuela Iezzi, Romina Marone, Stefano Marengo, Claudia Curcio, Christian Rommel

Sci Signal· September 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis